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Biomedical subjects

C Scherer

Publications and source records attributed to C Scherer.

31 records · Page 2Linked to original sources

[Contribution of vibration supported cementation on reconstructions].

A laboratory study was undertaken to investigate the influence of different types of cement and cementation techniques on the enlargement of the marginal gap of crowns. The crowns and preparations in the study were standardized; preparation forms were shoulder, chamfer and shoulderless. The cement brands were Harvard, Durelon and AquaCem. The enlargement of the marginal gap was measured for two different cementation methods: 1. Crowns were manually seated onto metal dies and subsequently loaded with 50 N constantly for 10 minutes 2. Crowns were manually seated on the dies and exposed to mechanical vibration from a Bergendal amalgam-condenser, subsequently loaded with 50 N constantly for 10 minutes. The comparison of both methods showed a 12-31% smaller vertical cementation gap enlargement of the samples that were treated with vibration. We recommend the clinical use of this method. Best results were achieved with AquaCem; Harvard showed the greatest difference when changing between the methods.

Crowns↗

[Economic aspects of use of alternative dental alloys].

A cost calculation for different types of dental alloys was carried through all stages of production. Recycling and scrap material values were included. Results showed that over an estimated 20 years of usage, the higher annual cost for bridges cast with a high gold alloy in relation to those with lower gold content alloys is not that significant that from the patients point of view the lower alloys should the choice. Due to the system of health insurance, this cost calculation from the production point of view looks different for the organizations that are reimbursing the patient for his expenses, as these organizations are not entitled to the scrap value of old restorations.

Cost-Benefit Analysis↗

[The neuromuscular effect of anterior guidance on the protrusive movement pattern of the mandible. Observations in the horizontal plane].

The influence of a temporarily altered anterior guidance on mandibular movement patterns of tooth-guided and non-guided protrusion was examined in a clinical study on 20 patients, all with complete sets of teeth. Registration and recordings of movements were done with the computer-aided ultrasonic measuring system MT 1602. Based on an average measuring time of 40 min for each patient the main results were as follows: 1. The shape of the anterior guidance strongly influences the horizontal tracings of tooth-guided and non-guided protrusion. In most cases these tracings show a deviation from the mid-sagittal path due to neuromuscular coordination. 2. Insertion of an idealized, symmetrical anterior guidance or a horizontal plateau lessens the mandibular deviation and harmonizes the tooth-guided and non-guided paths. However, the old neuromuscular engrams are not completely erased. 3. Newly formed engrams can be erased much easier than old ones.

Adult↗

[Evaluation and classification of dysfunction patients].

The "Stomatognathic-Dysfunction-Index" (SDI) comprises anamnestic and clinical information regarding occlusion, TMJ, head- and neck muscles. The different SDI parameters were chosen in a way that enables them to lead to a firm statement regarding the individual dysfunction. The examination results are easily reproduceable in the sense of a "intra- and inter-examiner reliability" and the scores can be reattributed to individual combinations of symptoms. The patients can be sorted into classes of dysfunction according to their total SDI-Score. This makes the SDI especially suitable for epidemiologic studies, but the easy handling of the SDI allows its use in private practice as well. Here it enables the dentist to classify patients with stomatognathic dysfunctions according to the necessity of treatment and sometimes to determine such necessity as well. The SDI is not meant to replace the extensive standard methods of clinical and instrumental analysis. It is meant to provide a maximum of diagnostic and therapeutic economic value from an affordable input of time in the everyday routine. It fulfills all requirements of an index for epidemiological studies.

Humans↗

[Determination of transverse resilience of human temporomandibular joint].

Transversal TMJ-resiliency is defined as a possible movement of the condyles exclusively in the lateromedial direction. The extent of this individual and variable shifting of the condyles can be recorded and reproduced using high-resolution electronic axiography and a special manipulating technique by the dentist. A study on 52 patients showed an average value of 0.3 mm for the transversal resiliency, which can be considered as physiological range. The results were discussed along with the question for the relevance of transversal TMJ-resiliency measuring regarding TMJ-disorders.

Humans↗

[Comparative analytic occlusal study of clinical use of T-scan systems].

Occlusal corrections are dependent on a precise registration. The T-Scan system has recently been presented to the market as an innovative, computer-aided device, capable of providing exact information regarding position, strength and frequency of occlusal contacts. The diagnostic validity of this technique was tested in a comparing study on 16 patients. The occlusal situation of these patients was analyzed by use of the T-Scan system and the markings compared with those obtained from UV-sensitive articulation foil. The results show that the diagnostic possibilities of the T-Scan system are very much limited. The use oft he T-Scan system as the only means of occlusal analysis cannot be recommended. The main reason for this is an often misleading reproduction of occlusal contacts, caused by the T-Scan-sensor-foil being too thick and too inflexible and therefore creating an uncontrollable shift of the mandibula when closing the bite. However, the T-Scan system seems to be a valuable tool for education of both students and patients, as the on-screen coulour display of occlusal mechanisms are really impressive.

Dental Occlusion, Balanced↗

[Bowenoid papulosis of the genito-anal region].

The recently described bowenoid papulosis of the genitoanal region is to regard as a new entity. Clinically the multiple lesions in the genitoanal region consist of red or brown papules. Histologically the lesions show dysplasia like the Bowen's disease. The bowenoid papulosis is a benign affection of young men and women. This disease is not rare. Retrospectively we found 22 patients. At this time the etiology is not known. The therapeutic possibilities are discussed.

Adult↗

Cytoreductive surgery for advanced stages of ovarian cancer.

During the past two decades, maximum cytoreductive surgery (also called debulking surgery) has been the recommended surgical approach for advanced stages of ovarian carcinoma. The residual tumor volume after surgery is one of the strongest prognostic factors, and only patients who undergo complete or optimal surgery are likely to be long-term survivors (i.e., 50% after five years). A well-trained surgeon in the field of gynecologic oncology can achieve an optimal tumor reduction in up to 75% of patients with advanced stage ovarian cancer. During the procedure, bowel resection, especially rectosigmoid, must be undertaken in 30% to 40% of cases, and para-aortic and pelvic lymphadenectomy should be performed after adequate tumor reduction in the abdominal cavity. The experienced surgeon can perform these surgeries with an acceptable morbidity, allowing chemotherapy to be undertaken within the month following surgery. However, very advanced cancer with massive peritoneal carcinomatosis and/or Stage IV disease requires a very aggressive surgical procedure but yields a poor prognosis and a higher risk of unacceptable complications. For these worst cases, the concept of cytoreductive surgery is moving toward the alternative strategy of chemosurgical cytoreduction, in which interval cytoreductive surgery is undertaken after three cycles of front-line chemotherapy. The goal of this experimental strategy is to achieve a complete tumor response after front-line chemosurgical therapy, and a better quality of life.

Feasibility Studies↗

Gerstmann-Sträussler-Scheinker disease with A117V mutation in a second French-Alsatian family.

We report a kindred of French/Alsatian origin with symptoms of Gerstmann-Sträussler-Scheinker disease over 3 generations. In the propositus, cerebellar signs and memory disturbance were the presenting features, followed by other neurological manifestations. Biopsy of the cerebral cortex showed numerous multicentric and "kuru"-type amyloid plaques that on immuno-light and electron microscopy stained with antibody to prion protein. Molecular genetic analysis revealed an A117V mutation in the open reading frame of the prion protein gene. Questions as to pathology and spread of this mutation are discussed.

Adult↗