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Biomedical subjects

C Scully

Publications and source records attributed to C Scully.

At least 37 records · Page 2Linked to original sources

The efficacy of management of acute dental pain.

The effectiveness of pain relieving treatments given for acute dental pain has been evaluated after 24 hours in 172 patients who presented to a dental hospital emergency department. Patients were contacted by telephone the day after attendance and graded their pain on a scale from 1 (no pain) to 5 (pain much worse). The mean pain scores for each diagnosis of cause of pain were calculated and related to the treatment given. Some 76% of patients were in pain due to the ravages of dental caries of periodontal disease. Overall, 87% received marked or total pain relief and this appeared to depend upon decompression of inflamed tissue. Oral administration of antimicrobial drugs alone produced little or no pain relief within 24 hours and anti-inflammatory analgesics offer poor pain control in these circumstances.

Acute Disease

Trends of oral cancer mortality among females worldwide.

Oral cancer incidence and/or mortality has been reported to be currently increasing in several countries, particularly those of central and eastern Europe. Most of these reports pertain to men, although increases in incidence among women also have been found. In this report, data from twenty-four countries in the World Health Organization's mortality database are analyzed. The widespread increase observed in oral cancer mortality among men is not occurring in women. Nevertheless, increases have occurred in several countries in Europe, and oral-cancer death rates--especially in central and eastern Europe--are likely to increase further if tobacco smoking, in particular, becomes more popular among younger women.

Adult

Rising trends of oral cancer mortality among males worldwide: the return of an old public health problem.

Oral cancer is considered widely to be a form of cancer whose etiology is well understood and which is becoming relatively rare in developed countries. There have been, however, a series of recent reports indicating that after many years of declining risk, the rates may be rising again in men. To investigate the extent of such changes, national time-series of oral-cancer mortality data available in the World Health Organization's mortality database have been analyzed. Age-period-cohort modeling was used to establish the extent and nature of these changes and to allow comparisons among countries. Nineteen out of 24 national datasets demonstrate a similar pattern of recent increasing cohort-effects for oral cancer in men. The largest increases have occurred in countries of central and eastern Europe where rates have increased by a factor of from three to 10 within a generation. The cohort-based nature of the changes observed in men suggest that there will be a continuing increase in the absolute numbers of cases of oral cancer to be treated in the coming decades.

Adult

Hereditary gingival fibromatosis. Report of an extensive four-generation pedigree.

A Brazilian family with hereditary gingival fibromatosis is described with multiple affected subjects in four generations. A total of 50 (48%), of 105 at-risk offspring in a family of 132 members were affected, consistent with an autosomal dominant mode of inheritance. This family appears to represent the largest pedigree with this condition reported in the literature.

Adult

Viral hepatitis. Current concepts for dental practice.

The transmission of blood-borne viruses in the dental office is a potential hazard to patients and dental staff, particularly to oral and maxillofacial surgeons. Hepatitis B virus has been a recognized hazard for several years, and in the past oral surgeons and other dental health care staff have been infected as a result of occupational exposure. Hepatitis C virus in contrast does not appear to be a major occupational hazard to dental staff, nevertheless, infection with this virus can lead to significant morbidity and may have oral manifestations. Hepatitis D virus can be nosocomally transmitted, but vaccination against the hepatitis B virus minimizes this problem. Hepatitis E virus is not of clinical relevance to dentistry, although dental staff who are in areas of endemic infection can become infected as a result of enteric transmission. A number of other putative viral agents may also cause hepatitis, but additional data is awaited, and their significance to dental practice is unknown. This article summarizes current data on hepatitis viruses A, B, C, D, and E.

Blood-Borne Pathogens

Willingness of Brazilian dentists to treat an HIV-infected patient.

A study of the willingness of 363 general dental practices in Brazil to accept a patient infected with human immunodeficiency virus for treatment of dental pain and the provision of routine dental care showed only 44% of dental practices to be willing to provide dental care. Willingness was influenced neither by financial factors nor the local prevalence of human immunodeficiency virus disease.

Adult

Autoimmune neutropenia manifesting as recurrent oral ulceration.

There are many causes of recurrent oral mucosal ulceration, particularly gastrointestinal, mucocutaneous, and hematologic disease. The present report details the features of a patient with recurrent oral ulceration caused by autoimmune neutropenia.

Autoimmune Diseases

Larva migrans that affect the mouth.

As air travel expands, tropical diseases are increasingly likely to be encountered. We report a case of a nematode infection from dogs and cats that appeared in the mouth as larva migrans, and we review the literature.

Adult

Oral melanotic macules that develop after radiation therapy.

External beam radiotherapy treatment of malignant conditions in the head and neck can give rise to several adverse oral effects if the oral or salivary tissues are within the field of beam. We report on a patient with widespread oral melanotic hyperpigmentation that developed after a course of radiotherapy for metastatic carcinoma in the cervical lymph nodes. As no other local or systemic cause was evident it is possible this abnormal hyperpigmentation was a result of the radiotherapy. The development of oral melanotic macules as a consequence of radiotherapy has not been previously described.

Carcinoma, Squamous Cell

Tongue piercing (oral body art).

Oral body art is a relatively recent fashion in the West where jewelry is inserted in the oral soft tissues. A patient who had tongue-piercing is presented, and the subject of oral piercing reviewed.

Adult