Loss of your mother is more than loss of a mother.
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Animals↗
Biomedical subjects
C Seiler
Publications and source records attributed to C Seiler.
[The immediate reconstruction of a large lip-chin defect with two muscular pedicled and innervated island flaps (author's transl)].
Different methods of defect closure in the lipchin region through lateral advancement-flaps have been described by Bernard, Fries, Hertig, Meyer and others. Is there not enough material available, can neck-, breast-or forehead flaps cover the defect, although they do not fulfill the demands for a satisfactory restoration of specific function. In the following work is the possibility of covering of a three layered facial defect with a combined skin muscle flap taken into consideration in view of the disadvantages of a simple or doubled skin flap. By this operation method the procedure consists of preparing various sized cervical island flaps which are connected with on the mastoid pedicled M. sternocleidomastoideus. We are describing a case of extensive tumorresection in the lip-chin area with neurofibromatosis Recklinghausen, whereby we have closed a large defect with two separately laid on muscle-pedicled, innervated island flaps from the fossa supraclavicularis. These bilateral compound flaps fulfill the demands of an immediate restoration of contour and prominence in this area. Apart from this they allow satisfactory voluntary activity, unpleasant dribbling of saliva is prevented.
Chin↗
[Sensorineural deafness and cochlear otosclerosis (author's transl)].
The so-called labyrinthine otosclerosis is defined as a focal otosclerotic involvement of the labyrinthine capsule without stapes fixation. It produces a pure sensorineural hearing loss. The histology of this phenomenon is well known. The relative frequency of labyrinthine otosclerosis is between 4 and 40%, as referred in literature. On x-rays, an advanced demineralisation or complete obliteration of labyrinthic bone is suspicious of otosclerosis. There is no typical pattern of sensorineural hearing loss. But not seldom a fair discrimination index contrasts with a severe threshold evaluation in pure tone audiometry. 208 audiogramms of otosclerosic ears verified by stapedectomy were examined. After correction for normal presbyacusis the sensorineural hearing loss due to otosclerosis is twice that of presbyacusis. In otosclerosis tinnitus is often reported as of metallic type, but a characteristic tinnitus does not exist. There is no universal agreement about the relative frequency of vestibular disturbances in otosclerosis. One should diagnose labyrinthine otosclerosis only if several criteria found are not explanable otherwise, and these criteria are explained.
Audiometry↗
[A survey about findings and courses of 300 facial palsies. A correlation of clinical and electrophysiological findings on computer (author's transl)].
A survey on 288 facial palsies in the years 1973 to 1975 is given. On a small computer (IBM 1800 was made a correlation of refined anamnesis and elaborate diagnostic findings. Nerve Excitability Test (NET) and Maximal Stimulation Test (MST) were mainly taken into account. The value of MST (i.E. Electroneuronography) for early prognosis of facial palsy is pointed out.
Computers↗
Organ donation--are we asking the right questions?
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Adolescent↗
Intraventricular blood flow during isovolumetric relaxation and diastole in hypertrophic cardiomyopathy.
Forty patients with hypertrophic cardiomyopathy were investigated by Doppler echocardiography for intraventricular blood flow abnormalities. None had a bundle branch block. The patients were recruited on the basis of the presence of at least one of four different types of abnormal left ventricular blood flow movements during systole, isovolumetric relaxation, and diastole (time after mitral valve opening). The abnormal blood flow patterns were composed of the following: (1) systolic left ventricular outflow and midventricular obstruction in 20 of 40 and in 6 of 40 patients, respectively; (2) retrograde isovolumetric relaxation flow (IVRFretro; mean velocity, 0.7 +/- 0.3 m/sec), that is, flow toward the apex of the left ventricle, in 28 of 40 patients; (3) antegrade isovolumetric relaxation flow (IVRFante; mean velocity, 1.6 +/- 1.0 m/sec), that is, flow toward the left ventricular outflow tract, in 3 of 40 patients; and (4) diastolic antegrade flow (DFante; mean velocity, 0.9 +/- 0.3 m/sec), that is, flow opposite to mitral inflow, in 10 of 40 patients. There were significantly fewer patients with asymmetric septal hypertrophy (group 1) than with apical hypertrophic cardiomyopathy (group 2) showing DFante (1/29 versus 9/11, p less than 0.01). IVRFretro and DFante revealed higher velocities in patients with marked left ventricular asymmetric hypertrophy than in those with mild hypertrophy. Thus, in hypertrophic cardiomyopathy and especially in patients with marked asymmetric hypertrophy, there are different types of abnormal intraventricular blood flow movements during isovolumetric relaxation and disatole. This phenomenon is probably caused by asynchronous relaxation of the asymmetrically distributed, hypertrophied myocardium. DFante is more often observed in the apical cardiomyopathy than other forms of hypertrophic cardiomyopathy probably attributable to apically localized left ventricular cavity obliteration.
Adolescent↗
Echocardiographic evaluation of left ventricular wall motion before and after heart transplantation.
Forty transplanted hearts were retrospectively investigated before, immediately after, and 15 +/- 12 months after heart transplantation by two-dimensional echocardiography for the presence and course of left ventricular myocardial wall motion abnormalities. Fourteen heart donors who were brain dead because of subarachnoid hemorrhage formed group 1 (mean age, 35 years); 21 heart donors who were brain dead because of head injury formed group 2 (mean age, 29 years), and five heart donors who were brain dead because of head injury with an additional chest trauma formed group 3 (mean age, 28 years). Myocardial wall motion was examined in six different myocardial segments (inferior, septal, anterior, posterior, posterolateral, apical) and was quantitatively assessed by a modified score index system (score index 0 = normal wall motion; score index 1 = diffuse hypokinesia). Overall, 27 of the 40 heart donors showed mild to severe (9 of the 40) wall motion abnormalities, which improved shortly after heart transplantation (score index: 0.36 vs 0.18, p < 0.01), and remained improved 15 months after heart transplantation (score index: 0.15). Among the different study groups, a significant improvement occurred in the myocardial wall motion score index on a short-term and long-term basis in all the groups, except for group 2, regarding the long-term follow-up. This study concluded that brain-dead, potential heart donors often reveal mild-to-severe left ventricular wall motion abnormalities, which are readily detected and semiquantitated by two-dimensional echocardiography.(ABSTRACT TRUNCATED AT 250 WORDS)
Adolescent↗
Circadian rhythm changes following maternal separation.
The monkey mother-infant separation paradigm is one of the best available animal models of grief and loss related depression. Because of the evidence implicating a relationship between disturbances in circadian rhythms and affective behavioral disorders, we studied circadian rhythms of temperature and heart rate in 10 group living infant pigtailed (M. nemestrina) monkeys during the affective behavioral reaction which accompanied 10 days separation from the mother. Best fit (least-squares method) cosine curves were computed for a total of 176 24-h periods for heart rate (HR) and 139 24-h periods for body temperature (BT), providing estimates of the fitted cosine level (approximating the mean value of the data), amplitude (half the value from the peak to the trough as the fitted cosine), and acrophase (time of fitted cosine peak). Significant decreases in cosine level, and delay in acrophase of 1-1.5 h, were found for both body temperature and heart rate during separation. Following reunion with the mother the acrophase occurred progressively later on subsequent days, suggesting possible free running rhythms. These data, in addition to reinforcing the relationship between circadian rhythm regulation and affective behavior, demonstrate that circadian phase shifts can be precipitated by disruption of an attachment bond without changing other circadian synchronizers, and support the view that disturbances in the regulation of circadian systems are one component of the reaction to loss or separation.
Animals↗