Biomedical subjects

C Sha

Publications and source records attributed to C Sha.

3 recordsLinked to original sources

PubMed2001

[Microsurgical treatment of apical region by combined orbital pterygoid approach].

OBJECTIVE: To study microsurgical treatment of orbital apical region tumor by combined orbital pterygoid approach. METHOD: In 21 cases, manifestations and surgical methods were analyzed retrospectively. The surgical approach and procedure were discussed. RESULTS: All the 21 cases were treated by combined orbital pterygoid approach. The tumors were removed completely in 18 cases, and partially resected in 3. There was no death. CONCLUSIONS: This kind of mass is difficult to explore by either transorbital or transcranial approach because of its position. Combined orbital pterygoid approach provides better access and exploration. Appropriate surgical approach, hemostasis and gentle microsurgical manipulation are the key to reducing postoperative complications.

Adolescent↗

PubMed2000

[Transoral microsurgical treatment of craniocervical malformation].

OBJECTIVE: To discuss transoral microcervical treatment of 16 patients with craniocervical malformation. METHODS: Perioperative treatment including antibiotics, tracheotomy, intravenous nutrition was used in 16 patients. RESULTS: Eight patients had basilar impressions, 3 chronic atlantoaxial dislocation and 2 odontoid fracture, 2 lower clivus chordoma, and 1 granuloma in the ventral part of the medulla oblongata. Three patients received bone graft. Follow-up for 6 - 36 months showed that 14 patients resumed normal life but 1 died. CONCLUSIONS: Pre-craniocervical malformation can be treated by transoral approach microsurgically. Understanding microanatomy of this approach can reduce postoperative morbidity and complications. Perioperative treatment can prevent incision infection. Prevention of intraoperative CSF leakage must be emphasized.Bone graft can make craniocervical spine stable.

Adolescent↗

PubMed1999

Studies on biosensor to determine diacetyl.

We studied the purification of diacetyl reductase, the preparation of a biosensor, and its performance. With diacetyl reductase and reduced coenzyme I (NADH) co-immobilized as working membrane, NAD+/NADH produced in the course of diacetyl reduction was connected with Fe2+/Fe to build a biosensor. The biosensor could be used to determine diacetyl concentration within the range from 0.1 microgram/mL to 0.5 microgram/mL and the response time was less than two minutes, and its performance was stable within 9 days. The experiments showed that typical metal ions and organics in nominal concentration did not affect the performance of the biosensor, meanwhile, the interference of dissolved oxygen on the performance of biosensor and regeneration of coenzyme I (NADH) were solved to some extent.

Acetoin Dehydrogenase↗