Biomedical subjects

C Short

Publications and source records attributed to C Short.

11 recordsLinked to original sources

PubMed1991

Issues relating to nutrient analysis.

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PubMed1989

Studies on the ability of smoke from different types of cigarettes to induce DNA single-strand breaks in cultured human cells.

In this paper we report preliminary studies using alkaline elution to examine the incidence of DNA-strand breakage in human lung cells exposed to smoke/phosphate-buffered saline generated from cigarettes of different tar contents and filter status. The majority of the DNA breaks induced were abolished by catalase indicating a role for active oxygen species. The incidence of breaks did not correlate with the tar content of the cigarettes. The presence of a filter in the cigarette reduced the TPM concentration of the mainstream smoke but did not reduce the number of single-strand breaks occurring in DNA after exposure to smoke/PBS. This last parameter was however reduced if the filter was ventilated.

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PubMed1989