[Acute hepatic and renal failure due to piroxicam use].
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Biomedical subjects
Publications and source records attributed to C Sillero.
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Solitary rectal ulcer is of varied etiology and the appearance of this syndrome due to Mycobacterium chelonae is exceptional. We present a case of a solitary rectal ulcer associated with Mycobacterium chelonae subspecies chelonae in an immunocompetent individual. This microorganism is involved in cutaneous, ocular, pulmonary and soft tissue infections. Treatment of infections has traditionally been surgical, although various antibiotic treatments have been used depending on the sensitivity of the microorganism, the severity of the infection and the surgical possibilities.
BACKGROUND: The aim of our study was to analyze the efficacy of cellulase in dissolving gastric phytobezoars. METHODS: We carried out a prospective study over a period of 1 year. All patients (7 cases) diagnosed as having gastric phytobezoar on gastroscopy were treated with cellulase. RESULTS: Complete dissolution of the gastric phytobezoar was achieved in all 7 patients. No side effects or recurrences occurred during follow-up. DISCUSSION: We conclude that cellulase should be regarded as the treatment of choice for gastric phytobezoars because of its efficacy, and because of the lack of side effects or recurrences. However, further clinical trials are necessary to verify these findings.
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Hemobilia is the term which describes the presence of blood in the biliary tract. We describe a case of symptomatic hemobilia after percutaneous liver biopsy which resolved spontaneously. We review the physiopathology of this complication and we highlight the role of abdominal ultrasonography not only in the diagnosis but also in the follow-up of hemobilia. In our case, abdominal ultrasonography was able to identify the probable point of bleeding.
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Sixty patients with bleeding duodenal ulcers were randomized to treatment with sucralfate or ranitidine. Endoscopy was performed in all patients within 24 hours from admission. Acute phase outcome was similar in both groups. Four patients in the sucralfate group and 1 patient in the ranitidine group rebled and required surgical treatment (NS). Healing rate at 6 weeks was 88% with sucralfate and 96.6% with ranitidine. Relapsing rate without maintenance therapy at 6 and 12 months was 21.1% and 42.1% for sucralfate-treated patients and 33.3% and 56.5% for ranitidine-treated patients (NS). Sucralfate-treated patients had a significantly lesser relapsing rate at 12 months compared to ranitidine treated patients, in the smokers group.
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A short-term double-blind study has been conducted to evaluate the clinical efficacy of diltiazem in 18 patients with irritable bowel syndrome, divided into two groups: group A, on the sequence placebo-diltiazem-placebo for three weeks. Group B, diltiazem-placebo-diltiazem for an identical period. The substance was administered in three daily doses of 60 mg prior to meals. Clinical manifestations and the general condition were evaluated after each period of three weeks following a pre-established score. Globally, it has been impossible to demonstrate the superiority of diltiazem over the placebo, but there seems to exist a trend to the improvement of diarrhoea and abdominal pain. It will be necessary to make an additional study to delineate the efficacy of this drug in the irritable bowel syndrome.
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