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Biomedical subjects

C Simoncelli

Publications and source records attributed to C Simoncelli.

At least 37 records · Page 2Linked to original sources

Giant cell reparative granuloma of the maxillary bone: case report and review of diagnostic criteria.

This paper reports a case of giant cell reparative granuloma of the right maxillary bone of a 13-year-old caucasian girl. It may be very difficult to distinguish this entity from other lesions of mandible, maxilla and skull bones which contain multinucleated giant cells. The differential diagnosis, especially from giant cell tumors of the bone, is discussed. Accurate diagnosis lies on correct integration of clinical, radiographical and histopathological data.

Adolescent↗

[Short-term reproducibility of acoustic oto-emissions induced by clicks in adults].

Otoacoustic emissions (OAE) are sounds emitted by the cochlea and recordable in the external ear canal by a miniature microphone. The OAE reflect the existence of an active mechanism within the cochlea. Development of the OAE has spurred much interest because they may used as a valid test for screening and monitoring cochlear changes. The OAE were recorded in 8 normal hearing subjects (15 ears) during nine test sessions under similar conditions. The aim of this work was to study the short-term variability in the amplitude of the emissions. Results of the study indicate that response levels are stable over time in the same ear therefore changes in the response level can be associated with changes in the cochlea.

Acoustic Stimulation↗

SSR-40Hz electrogenesis: results of clinical investigation.

This study attempts to provide clinical evidence on the origin of SSR-40Hz auditory evoked potential studying posttrauma coma patients. The SSR-40Hz present two types of morphology: an acute narrow wave, defined as "sharp", and a slow wide curve defined as "rounded". In constant recording of auditory brainstem responses (ABR) the "sharp" wave correlated with the absence of middle latency responses (MLR), and the "rounded" with their presence. In some patients the morphology changed passing grom a "sharp" to a "rounded" wave and a tendency towards widening preceded the appearance of middle latency responses. Perhaps the functional electrophysiologic block may have diminished in sub-cortical neuronal areas not involved in MLR genesis.

Adolescent↗

[Evoked acoustic oto-emissions in patients with diabetes mellitus].

The purpose of this study was to evaluate the cochlear function in patients with diabetes mellitus by analysis of evoked otoacoustic emissions (EOAE). EOAE were studied in 20 diabetic patients with normal hearing. The parameters used for analysis were the EOAE intensity and amplitude measured per 100 Hz frequency bands between 700 and 4000 Hz These data were compared to the data obtained in a group of non-diabetic control subjects with normal hearing using a Student's t test. The mean EOAE intensity and amplitude by 100 Hz frequency band was significantly lower in diabetic patients than in the control group. This seems to indicate the existence of an alteration in cochlear micromechanics in diabetic patients possibly due to changes in the functioning of the hair cells.

Adult↗

[Evoked otoacoustic emissions in diagnosis of cochlear hearing disorders].

The authors consider the possibility of routine use of evoked otoacoustic emissions (EOE) in diagnosis of sensory hearing loss by comparison of EOE curves with relative curves obtained by pure tone audiometry. 180 ears with sensory hearing loss of different aetiologies were examined. EOE were obtained by application of Bray and Kemp's Evoked Otoacustic Measurement Package (ILO88). The results obtained show a close correlation between presence of EOE and real hearing losses of different frequencies obtained by pure tone audiometric evaluation. We could detect no EOE with hearing losses over 50 dB HL at 500 Hz, 40 dB HL at 1000 Hz, 50 dB HL at 2000 Hz and 85 dB HL at 4000 Hz. With a rate of middle hearing loss over 45 dB HL we also did not find EOE for the whole frequency range. On the base of this study, the authors conclude that EOE explore the functional integrity of those parts of the cochlea that correspond to the middle frequencies of hearing range. If EOE are not detectable, statements on the nature and extent of hearing loss on the base of this examination are not valid.

Adolescent↗

[Results of audiometric and vestibular tests in Cogan syndrome: apropos of a case].

The authors report on a case of Cogan's syndrome pointing out that hearing loss is due both to cochlear lesions from likely immunitary origin as well as to widespread alterations of auditory central nervous structures. This interpretation allows to explain the apparent discrepancy of the found clinical and instrumental data. From a therapeutic point of view, the authors assert the necessity of an early corticosteroid therapy to obtain some appreciable result. Anyway, they point out how prognosis for auditory function in Cogan's syndrome is often very poor.

Adult↗

[Evoked oto-acoustic potentials in the first 60 hours of life].

In order to verify how age influences in the first days of life the presence of Evoked Otoacoustic Emissions (EOAE), the authors tested 52 newborns. They conclude that EOAE is a reliable technique as an early detection test of hearing loss in children. However, a high percentage of false positive cases during the very first days of life advises against its too early utilization.

Evoked Potentials, Auditory, Brain Stem↗

[Bacteriology of chronic maxillary sinusitis].

132 patients with chronic maxillary sinusitis were included in this bacteriological study of the intrasinus exudate obtained by a radical antrostomy or antral puncture. We found 78.3% aerobes, 21.7% anaerobes, 51.5% gram positive and 48.5% gram negative micro-organisms, but no fungi in 120 cultures. The commonest aerobic species was Haemophylus (20%), whereas Peptococcus and Bacteroides were the commonest anaerobes (10%).

Adolescent↗

[Evoked oto-acoustic emissions (EOE) as screening method in infants].

The authors consider the problems of the early diagnosis of paediatric hypoacusis, presenting a study done on twenty audiological high risk children that were subjected to audiometric screening by delayed cochlear otoacoustic emissions (EOE) and brainstem auditory evoked potentials (BEAPs). Eighteen of twenty children that were examined were normal, while two had bilateral sensorineural hearing loss. EOE were evoked in all patients that presented normal BAEP thresholds, while they were absent in deaf subjects. Evoked otoacoustic emissions research allows us to identify two groups of subjects: those with normal EOE who can be considered normal hearing subjects, and those without EOE who may present a disturbed auditory system. Nevertheless, EOE testing does not allow us to judge the type of hearing loss. The time for EOE testing is approximately five minutes for each subject. On the grounds of their experience, the authors conclude that EOE testing represents a useful and reliable test which differentiates normal auditory function subjects from hypoacoustic ones. Compared to other techniques used in audiological paediatric diagnosis, such as reactometry, BOEL test and Crib. O. Gram, which present the possibility of false positive and false negative results, and BSERA, which even if reliable, must be limited to few selected audiological high-risk subjects, EOE is easy to implement and readily available. Major limitations of this technique seem to be the possibility of false positives, and the impossibility to specify localisation and type of the hearing loss by EOE only.

Cochlear Microphonic Potentials↗

Whole-blood filterability in sudden deafness.

Sixteen patients with sudden deafness (SD), diagnosed on the basis of a battery of audiometric tests, but with no other medical or surgical pathology requiring drug treatment, underwent monitoring of their hemorheological profiles to see whether disturbances in the microcirculation could be linked to SD. Plasma viscosity, the filterabilities, (using a low-shear positive pressure system) through 5-microns-diameter pore Nuclepore filters, of whole blood and red and unfractionated white cells were monitored in 16 SD patients and 32 controls matched for age, sex and socioeconomic status. Whole blood filterability and the filterability of the red blood cells were significantly impaired in the SD patients, which suggests that alterations in the microcirculation are linked, in some way, to sudden deafness.

Adult↗

Post-traumatic paralytic syndromes of the jugular and condylar foramina.

The fact that neoplasms of the cranial base or metastases of nasopharyngeal tumors may cause palsy of nerves which pass through the jugular and anterior condylar foramina has been well documented. On the other hand, very little has been reported about the traumatic causes of these diseases, probably because they are often underestimated or misdiagnosed. In this paper, the Authors report four cases of palsy of the last four cranial nerves caused by various kinds of trauma: glossopharyngeal thermo-rhizotomy, bullet wound, closed cranial trauma, neck surgery. The main symptom immediately following a lesion is mechanical dysphagia which causes inhalation of food and saliva and may sometimes require surgery, such as tracheotomy or cricopharyngeal myotomy. The most lasting symptom is dysphonia, which can only be treated by speech therapy. Because of the importance of these damaged functions, the above symptoms must be studied more thoroughly, also keeping in mind the modern techniques of surgical and non-surgical speech rehabilitation.

Aged↗

[Submaxillary gland excisions: a retrospective investigation].

Swellings of the submaxillary region are very frequent in otorhinolaryngology clinical practice. The authors of this study analyzed 106 cases of submaxillary gland excision under their observation, emphasizing their epidemiological, clinical and anatomopathological aspects which could be useful during the diagnostic and therapeutic phase of the submaxillary gland affections. They also made a comparison with the data already published on the same subject.

Adult↗

Arteriovenous fistula of the mandible: a review of the literature and report of a case.

The authors, after a careful review of the literature during the last 15 years concerning arteriovenous malformation (AVM) of the jaws, report a case of congenital arteriovenous fistula of the mandible characterized by several episodes of spontaneous hemorrhage requiring emergency hemimandibulectomy. Radiologic, arteriographic and pathologic aspects of this lesion are discussed. Even though nomenclature concerning AVM of the jaws is confusing the authors draw attention to the embryologic features which are responsible for these lesions. They also point out the main diagnostic and therapeutic aspects emphasizing the small effect that ligation of the external carotid artery has on bleeding and the importance of choosing case by case the best treatment considering the great variety of clinical and pathologic aspects that characterize these lesions.

Arteriovenous Fistula↗