Prestorage leukocyte depletion is not necessarily required for the prevention of refractoriness to platelet transfusion.
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Acute Disease↗
Biomedical subjects
C Smit Sibinga
Publications and source records attributed to C Smit Sibinga.
Financial aspects of hemophilia care.
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Cross-Cultural Comparison↗
A scheme for the future.
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Comprehensive Health Care↗
Supply and need of factor VIII concentrates.
Demand for factor VIII varies greatly and exceeds supply in many places. Logical analysis of this difficult situation has been undertaken by observing actual usage, calculating potential need, and analysing factors which limit or influence production and distribution. Usage exceeds production potential in some places. It is concluded that factor VIII production/usage in the range of 20 000-60 000 IU per hemophilia A patient per year is both feasible and adequate. Production/use below 10 000 IU is not adequate. Production above 60 000 IU is not practicable using current technology.
Factor VIII↗