PubMed Health⌕ Search

Biomedical subjects

C Smuckler

Publications and source records attributed to C Smuckler.

2 recordsLinked to original sources

[Multiple cerebral hydatid disease].

A case of hydatid cerebral disease with multiple cysts is reported with the purpose of presenting this unusual form of hydatid neurological involvement and to discuss some aspects of the pathogenesis and treatment. In this patient, the liver hydatid cyst surgery two years prior to the development of multiple pulmonary and cerebral cysts suggests a vascular invasion of oncoesphere during the hepatic surgery with hematological dissemination to the lungs and brain. The multiplicity and deep localization of the cerebral cysts prevented the performance of a definitive surgical resection. The multiple percutaneous drainage of the cysts was useful in this case to reduce the endocraneal hypertension and to achieve a neurological improvement. Albendazole has proved of benefit as a chemo-therapeutic agent in these cases and Magnetic Resonance Imaging has proven useful for surgical planning.

Adult↗

[Rhabdomyolysis associated with an iodinated contrast media].

A case of rhabdomyolysis associated with an iodinated contrast medium (sodium diatrizoate) in a patient with chronic renal failure is presented for the purpose of discussing this association. Clinical manifestations were: diffuse myalgias, proximal muscular weakness and an acute reversible deterioration of the renal function. Muscle biopsy showed the typical pattern found in rhabdomyolysis, that is, cellular necrosis with no inflammation signs and myolytic areas. The temporal association between the rhabdomyolysis and the use of the contrast medium suggests a causal relationship. The present case allows us to postulate that the skeletal muscle injury was secondary to direct toxicity and/or the compromise of muscle blood perfusion by the contrast medium in a susceptible muscle due to previous renal failure. It is suggested that this group of substances should be incorporated to the list of agents capable of causing non traumatic rhabdomyolysis.

Adult↗