PubMed Health⌕ Search

Biomedical subjects

C Sors

Publications and source records attributed to C Sors.

At least 19 recordsLinked to original sources
PubMed1987

[Current aspects of bronchial tuberculosis].

The authors report a retrospective study of 34 cases of bronchial tuberculosis observed between 1981 and 1985 with precise endoscopic and histological data. Analysis of the population showed a male predominance (71 p. 100) and a high incidence of black Africans (54 p. 100), much higher than that observed in the general population of tuberculosis in our department (20 p. 100 of black Africans). Three groups of patients were identified with respect to age: group I, 23 patients aged 18 to 32 years; 22 of these patients were black Africans (98 p. 100) with primary tuberculosis; group II, 4 patients aged between 44 and 56: all were immunocompromised; group III, 7 patients over 65 years of age with reinfections: 6 of these 7 patients were French nationals. Apart from the specific problem of immunodepression observed in group II, two distinct features were identified: the primary lympho-bronchial infection of the young African and tuberculous bronchial reinfection of European women over of the age of 65.

Adult↗
PubMed1986

[Routine use of 6-month antitubercular treatment in 300 patients].

Over a 2-year period, all patients with incipient tuberculosis seen in a hospital unit were given a 6-month treatment consisting of rifampicine, isoniazide, pyrazinamide and ethambutol. A retrospective study of these 300 patients showed that the treatment was effective, with no failure if taken for more than 2 months. Relapses were rare when the drugs were taken regularly, the responsible M. tuberculosis strain was sensitive, and there was no associated malignancy (present in 1.4% of the cases). The drugs were moderately well tolerated, and treatment had to be modified because of side-effects in 4.6% of the patients. It also appeared that 57% of the patients fully complied with the prescription, and 16% were lost sight of by the hospital unit. Treatment was altered in 36% of the cases, but in 16% changes were introduced by private doctors for reasons which retrospectively proved to be without medical grounds. It is concluded that this 6-month chemotherapeutic regimen was effective in more than 98% of the cases, and that the main problem in management of tuberculosis is the patient's compliance with treatment.

Adolescent↗
PubMed1985

A comparison of flunisolide inhaler and beclomethasone dipropionate inhaler in bronchial asthma.

Ninety-nine patients, who had never previously taken inhaled steroids were enrolled in a randomized, single-blind, parallel study, the aim of which was to compare the efficacy and safety of flunisolide inhalation, 500 mcg twice daily, with beclomethasone dipropionate inhaler 100 mcg four times daily for the treatment of chronic asthma. The treatment period was for 6 weeks. The patients were examined clinically at entry, week 3 and week 6 and both treatment groups showed a marked improvement in almost all parameters during the course of the study. Flunisolide was statistically significantly superior to beclomethasone dipropionate for wheezing at week 6, coughing at week 6 and chest tightness at weeks 3 and 6. The number of asthma attacks per day decreased significantly more with flunisolide treatment than with beclomethasone dipropionate. The over-all evaluation of efficacy by both doctors and patients also showed flunisolide to be superior to beclomethasone dipropionate. In several other parameters there was a trend shown favouring flunisolide, and beclomethasone dipropionate did not show a superiority over flunisolide in any efficacy parameter. Both drugs were well-tolerated, with unpleasant taste being the most frequent complaint in the flunisolide group. No patient in either group withdrew from the study because of adverse events. In this study, flunisolide inhaler was more effective than beclomethasone dipropionate inhaler for the treatment of chronic asthma exhibited by patients who had never been treated with inhaled steroids.

Adolescent↗
PubMed1979

[Study upon oxygen conveyance in severe anaemia. About a very serious case of hemolytic anaemia which led to a myocardial infarct (author's transl].

To understand the orientation the metabolism of a sick person whose arterial content in oxygen had collapsed (CaO2 reaching 1,9 vol/100 ml) the cardiac output and the rate myocardic extraction of the lactates have been measured. The cardiac index was very high 7,4 l/m/m2 and in spite of a low D (a-v) (2,5 vol/ml) the consumption of oxygen was normal. Three days after a first measure the steep (or brutal) fall of the cardiac and the reversal of the rate of myocardic extraction of lactate led up to diagnose an acute coronary insufficiency. The electrocardiogramm only cortoborated the myocardic necrosis in a second time. This result invites (or calls for) a constant electrographic watching of sick persons who suffer from severe anaemia, even with sane coronary vessels, to avoid diagnosing coronary insufficiency through so circuitous means.

Anemia, Hemolytic↗
PubMed1979

[Cytoenzymological, immunological and scanning electron microscopic studies on 49 cases (author's transl)].

Light cytology, enzymology, immunofluorescence and scanning electron microscopy have been performed on 49 bronchoalveolar fluids recovered by bronchoscopic lavage. The patients had the following lung diseases: infectious pneumonitis (19 cases), pulmonary fibrosis (13 cases) including 5 sarcoïdosis, 3 idiopathic pulmonary fibrosis and 5 silicosis, hypersensitivity pneumonitis (5 cases) and miscellaneous lung tumors (12 cases). Cytologic studies in comparison with clinical aspects show 4 groups: Group I (chronic bronchopneumopathy and inactive fibrosis) presents numerous cells but few lymphocytes (less than 5%); in Group II (evolutive fibrosis) have an increase percentage of lymphocytes (20%); in Group III (hypersensitivity pneumonitis) is observed a very high percentage of lymphocytes (45%); and in Group IV (cancerous lung diseases) values are not far from normal percentage except for lymphomas. Small macrophages (diameter: 10 microns) with a central monocytoïde nucleus and few cytoplasma, are abundant in groups II and III where lymphocytosis is higher. Scanning electron microscopy shows irregular and rough surface, and numerous spontaneous adherences with erythrocytes, lymphocytes, or bacterias. Enzymatic activity (acid hydrolase, esterase, oxydase) increases in these cells. Lymphocytes have a smooth surface ovocative of T origin which is confirmed by granular acid phosphatase positivity and rosette forming test. Immunofluorescence shows positive granules with IgG, C1Q and C3 in macrophages only for Groups II and III while free immunoglobulins were present in the recovered lavage fluid.

Bronchi↗
PubMed1979

[A comparative study of three procedures used for studying bronchopulmonary bacterial flora (author's transl)].

Three methods of taking samples of bronchopulmonary secretions; transtracheal aspiration (TT), sputum collection, and fibro-aspiration, were compared in 43 patients with severe pneumopathies. There was no significant difference in the number of times a pure or dominant germ was isolated by using the three procedures in these 43 cases. In contrast, however, there was a significantly lower number of polymorphous flora and more sterile samples observed when using TT than with the other two methods. When antibiotics are given 1 to 7 days before taking the samples, there is a significant reduction in the number of cultures having a germ in the pure state.

Adult↗
PubMed1979

[Modalities and interest of preoperative staging in primary lung cancer (author's transl)].

The study of the extension of primitive lung cancer involves, on one hand, the determination of the locoregional extension concerning the tumator and adenopathies, and on the other hand, the determination of the metastatic extension. A careful clinical examination determines the need for complementary examinations providing decisive information for or against interventions. Systematic lung endoscopy should consist of staged biopsies. Mediastinoscopy estimates the locoregional extension in a more satisfactory manner than angiography or lung scintigraphies. The search for bone or cerebral metastasis is often negative in the absence of clinical symptomology in spite of the recent contribution of tomodensitometry. The detection of abdominal metastasis by biological examination, scintigraphies or contrast X-rays is liable to interpretational errors in one-third of the cases. It is for this reason that we preconize laparotomy before lung exeresis. In our series, among 175 laparotomies, 35 revealed abdominal metastasis whose discovery enables us to avoid useless, if not harmful, thoracic surgery.

Abdominal Neoplasms↗