Axonal growth and pathfinding: from phenomena to molecules.
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Animals↗
Biomedical subjects
C Stürmer
Publications and source records attributed to C Stürmer.
Origin of centrifugal fibers to the labyrinth in the frog (Rana esculenta). A study with the fluorescent retrograde neuronal tracer 'Fast blue'.
After injecting a solution of a fluorescent retrograde neuronal tracer (Fast blue, Diamidino compound 253/50) into the perilymphatic space of the frog labyrinth (Rana esculenta), labeled cells were found in the ventral and dorsal nuclei of the VIIIth nerve and in the nucleus reticularis medius. We consider these labeled cells to be the origin of the efferent innervation of the frog labyrinth. No evidence was found for the existence of a direct cerebello-labyrinthine connection.
Afferent Pathways↗
Electron microscopical identification of 3,3',5,5'-tetramethylbenzidine-reacted horseradish peroxidase after retrograde axoplasmic transport.
Tetramethylbenzidine (TMB) histochemistry for retrogradely transported horseradish peroxidase (HRP) has been successfully applied in electron microscopical preparations in the guinea pig visual cortex. In ultrathin sections, the TMB--HRP reaction product appears as an accumulation of typical electron-dense crystals. These crystals were identified in the cytoplasm of labeled cells in the proximal portions of the dendrites, and in myelinated axons. It is demonstrated that the TMB--HRP method is well suitable to analyze the ultrastructure of labeled cells and their synaptology.
Animals↗
Origin of efferent fibers of the vestibular apparatus in goldfish. A horseradish peroxidase study.
After injecting a horseradish peroxidase (HRP) solution into the vestibular apparatus in goldfish (Carassius auratus), cells in the medulla oblongata exhibited retrogradely transported HRP reaction product. These labeled cells were confined to 3 nuclei, i.e. the nucleus motorius tegmenti of Bartelmez (with the most prominent labeled cell groups), the ventral vestibular nucleus (Dieter's nucleus) and the medial vestibular nucleus. We consider these labeled cells to be the origin of the efferent innervation to the vestibular apparatus in goldfish. Neurons providing efferent innervation to the sensory periphery in the nucleus motorius tegmenti have, as yet, not been described.
Animals↗