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C Stănescu

Publications and source records attributed to C Stănescu.

36 records · Page 2Linked to original sources
PubMedDate not supplied

[Single-stage operation in simultaneous pulmonary and liver hydatic disease].

The most frequent association of hydatic disease lesions is hepatic and pulmonary localisations. It is generally admitted that surgical treatment is the only effectiveness treatment in hydatidosis. The classic approach is the two-stage surgical interventions of pulmonary and liver localisation or one-stage extensive thoraco-phrenic-laparotomy, exclusively reserved to right pulmonary hydatic cysts associated with hepatic dome localisations. The study presents single-stage operation by thoracotomy or mini-invasive thoracic surgery and laparotomy or laparoscopy, or single-stage thoracic approach, as alternative of classic attitude and evaluates the results in 10 patients with synchronous pulmonary and liver hydatic cysts. Overall observations are-encouraging.

Adult↗
PubMedDate not supplied

[Minimally invasive combined surgical treatment in a case of bilateral pulmonary hydatidosis].

The minimally invasive surgical techniques had an explosive development in the last 15 years. In thoracic surgery, these techniques were rapidly adopted, especially because of medical advantages, but also for aesthetic reasons. We present the case of a 33 years old patient, with bilateral pulmonary hydatidosis, treated in one-stage surgery, by VATS (video-assisted thoracic surgery) and thoracoscopic approach. The post-operative course was uneventful and the patient was discharged in five days. In selected cases, of patients with uncomplicated hydatid cysts, the minimally invasive surgical approach is not only possible, but probably also indicated.

Adult↗
PubMedDate not supplied

The onset and progression of atherosclerotic plaques as related to arterial wall changes.

The coronary arterial beds from more than 1200 subjects aged 1 to 65 years were investigated by both histopathological, histochemical and morphometric methods. Light microscopic aspects were analysed to reveal if plaque development and progression toward obstructive lesions were associated with arterial wall changes, particularly of the intimal connective tissue adjacent to lesions. Six patterns of plaque development in the coronary arterial tree were delineated, emphasis being placed on the observation that the onset and progression of plaques frequently appeared independent of arterial wall changes, in contrast to fatty streaks, gelatinous lesions, intimal necrotic areas, incorporated microthrombi and intramural thrombi. Our results support the view that plaques develop and progress on their own, superimposed on a preexisting arterial wall microarchitecture.

Adolescent↗
PubMedDate not supplied

Influence of coronary heart disease risk factors (CHDRFs) on the natural history of coronary atherosclerosis as revealed by a post-mortem study.

A postmortem study was carried out on the whole coronary arterial bed of 430 selected apparently healthy subjects, aged 38 to 65 years, in an effort to reveal the influence exerted by coronary heart disease risk factors (CHDRFs) on the development of coronary obstructive plaques. A clear positive correlation was found in 31% of cases and in more than 50% of 28 selected topographic sites of the coronary arterial bed. On the other hand, the subgroup without CHDRFs also exhibited severe coronary narrowings. Each major CHDRF seems to exert its particular action on selected regions of the coronary arterial bed: proximal or intermediate segments of the major coronary arteries; branching points; nonbranched areas; vessels supplying the conduction system, etc.

Adult↗
PubMedDate not supplied

Diagnosis of pneumococcal meningitis by coagglutination method.

It was tested the possibility to evidence the pneumococcal capsular antigen, by coagglutination, directly in CSF, using a specific coagglutinating reagent for all the 10 serological types of S. pneumoniae more frequently encountered in our country. Were investigated 134 CSF from purulent meningitis, out of which 37 were of probable pneumococcal etiology, on the basis of bacterioscopic examination, 26 of other etiology and 71 of unknown etiology. The results obtained showed 28 (75.7%) positive reactions in the fluids from probably pneumococcal meningitides on the basis of the positive bacterioscopic examination. The specificity of the reactions is demonstrated by the negative reactions with the fluids from meningitides of other etiology, as well as by the concordance between the antigen serotype from the liquid and that of the isolated S. pneumoniae strain. For a good test sensitivity could argue the positive reactions obtained with 6 CSF from meningitides of unknown etiology.

Agglutination Tests↗
PubMedDate not supplied

The improper use of the term "normal" in atherosclerosis research.

The improper use of the term "normal" was frequently detected in the available literature, in studies dealing with coronary artery anatomy, pathology and angiography, as well as in epidemiological investigations. Many examples are presented which try to demonstrate that without a clear understanding of the normal, it is a very difficult task to explore the abnormal during coronary atherogenesis and the successive stages which form the natural history of coronary atherosclerosis.

Animals↗
PubMedDate not supplied

[Results of the use, for a period of 3 years (1974-1977), in pilot districts, of the complex program of measures for prevention of streptococcal infections and their complications].

Starting with the year 1974 a total 11 pilot units have been organized, in as many counties in which a complex program of surveillance of streptococcal infections was applied, that had the following objectives: 1. Prevention and fight against acute streptococcal infection ; 2. Prevention of severe complications of acute rheumatic fever of rheumatic carditis and acute glomerulonephritis ; 3. Prevention of relapses of acute rheumatic fever. The establishment and verification of methods for clinical and laboratory diagnosis was followed, as well as of therapeutic techniques and dispensarization. The analysis of results obtained after the application for a period of 3 years of the program in high-risk collectivities, and in the conditions of an intensive circulation of some epidemic strains of streptococcus has shown the decrease each year of the incidence of scarlet fever, the increased efficiency of detection of acute non-eruptive (non-rash) streptococcal infections, as well as a significant decrease in the number of cases that developed a first attack of acute rheumatic fever and acute glomerulonephritis. A significant decrease was also obtained in the number of relapses and of severe evolution of rheumatic carditis, due to active detection, continuous evidence, prophylaxis and periodic control of cases with acute rheumatic fever.

Anti-Bacterial Agents↗
PubMedDate not supplied

The Bucharest multifactorial prevention trial of coronary heart disease. General methodology and risk factor correction after five year follow-up (1971-1977).

Both the intervention and the control group included each 5000 men aged 40-60 years, randomly selected by their home address in five districts of the city of Bucharest. The intervention group underwent an "at entry" examination for risk factor detection (high serum cholesterol, high blood pressure, overweight, diabetes, minor ECG abnormalities, family history) and subsequently a five-year multifactorial intervention aimed to reduce the risk factors. Both groups were followed up in this lapse of time for major end-points: myocardial infarction, stroke, sudden death. The qualitative analysis of the results used ten evolution indices based on a quantal counting and lead to a classification of risk factors which allowed the setting up of a strategy for their correction. The quantitative analysis showed the following decreases between the first and the last examination in the intervention group: for serum cholesterol greater than or equal to 250 mg/dl -17%; for cigarettes/day greater than or equal to 15-53%; for overweight greater than or equal to 30% - 13.57%; for high blood pressure -8%; for the overall risk computed by multiple regression -33.8%.

Adult↗
PubMedDate not supplied

Dobutamine stress echocardiography.

Echocardiography is a very good technique for the analysis of total and regional left ventricular wall motion. It can be used, in conjunction with a protocol for either exercise or pharmacologic cardiovascular stress, to identify the presence and distribution of coronary artery disease. The presence of myocardial ischemia is proved by the induction by a regional left ventricular wall motion abnormality. The use of dobutamine infusion as a stress test associated with echocardiography is a practical method, safe and accurate for the diagnosis of coronary disease in patients unable to exercise. Dobutamine stress echocardiography can also be used for assessment of risk and patient prognosis after acute myocardial infarction and as an indicator of myocardial viability.

Dobutamine↗
PubMedDate not supplied

Hypertrophic cardiomyopathy in old agers. Definitions and general considerations.

Hypertrophic cardiomyopathy (HCM), a primary heart disease, in most of the cases genetically transmitted, characterized by hypertrophy, often asymmetric, of the left ventricle (LV), presents certain peculiarities in old agers. The shape of the LV in old agers, is characterized by aorto-septal angulation, by the frequent presence of a septal bulge and the calcification of the posterior mitral ring which contributes to the narrowing of the LV ejection tract by the anterior displacement of the mitral valve. Thus, HCM in old agers can also have an acquired component associated with the mild changes of aging, which in certain conditions can lead to the appearance of some peculiar forms of disease.

Adult↗