[Epithelioid leiomyoma of the stomach--differential diagnosis and malignity].
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Biomedical subjects
Publications and source records attributed to C Stambolis.
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A case of a solid and cystic acinar cell tumor or pancreas is reported. The macroscopic and microscopic features, the ultrastructure, the immunocytochemical characteristics and the typical epidemiology of this extremely rare and, since a short time, new entity are depicted. The differential diagnosis to other tumors of the pancreas is discussed.
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Absorbable and non-absorbable suture materials were compared in microsurgical end-to-end-suture of the aorta in rats. Individual differences in tissue reaction were excluded by using the different materials in the same animal and the same organ. The use of absorbable suture materials needs longer practice as it is difficult to handle. Leaking anastomoses did not occur. Anastomoses were examined by light- and scanning electron microscopy. Both materials show similar neo-intima. Non-absorbable suture material shows greater tissue reaction which is also more persistent.
Using KCl-tumor extracts from various human carcinomas we tried to improve the reliability of the electrophoretic mobility test (EMT). 25 of 26 patients with histologically proven gastric cancer showed a correct positive reaction if tested with gastric cancer tumor extracts. 44 of 50 healthy controls showed negative test results when tested with the same tumor extracts. Migration inhibition in the tumor patients differed significantly from that of the healthy controls (p less than or equal to 0,05). Specificity was verified by testing gastric cancer patients with extracts from tumors of the same organ as well as different carcinomas: the most pronounced migration inhibition was observed, when gastric carcinoma extracts were used. Tumor extracts of different histogenesis showed weaker or negative reactions. Inflammatory lesions reduce the reliability of the test system: of 17 patients with ulcers or erosive gastritis 9 had false positive reactions.
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The extraordinary results of treatment of Wilms' Tumor has made it a model for interdisciplinary treatment of malignancies in children. Grouping by pathological and clinical findings helps to estimate the prognosis and to establish an individual therapeutic protocol. Since 1972 the overall 5 years survival rate of our patients (n = 30) is 86%.
3 children with malignant tumors in one kidney were treated with radiation in doses of 30 (3 weeks), 35 (6 weeks), and 33 Gy (8 weeks). The clinical and histological findings of radiation-induced nephritis from 2 children are demonstrated. In the third case radiation was performed because of adrenocortical carcinoma. 10,5 years after radiation the child developed a renal cell carcinoma.
A case of true congenital nephroblastoma is reported. The macroscopic and histologic features of this extremely rare renal lesion are depicted in detail and compared with those of congenital mesoblastic nephroma (fetal mesenchymal hamartoma).
A benign cystic nephroblastoma in a 6-month-old boy is presented. Erroneous interpretation as malignant nephroblastoma led to unnecessarily aggressive therapy. There is no evidence of recurrence or metastatic disease 12 years after the initial resection. As shown in our case and in the others previously reported in the literature, benign cystic nephroblastoma represents a distinct clinicopathological entity which does not show malignant behavior.