Seminal plasma proteins and semen characteristics in relation with fertility in the stallion.
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Biomedical subjects
Publications and source records attributed to C Stanciu.
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BACKGROUND/AIMS: A hospital ethics committee (EC) is an organized body of people, convened to identify, analyze and help resolve moral problems that arise in the care of patients. The aim of this study was to investigate the need to educate endoscopists about the role of the ECs in European and Mediterranean countries. METHODS: A structured questionnaire concerning the role of ECs was sent to the representatives of endoscopy societies, which are also members of the European Society of Gastrointestinal Endoscopy. RESULTS: The response rate was 59% (26/44). About half of the responding representatives had attended more than 1 lecture or read more than 1 article about ethics during the previous 10 years. The percentage of hospitals with an established EC varied between countries. In 15% of the countries <20% but in 58% of the countries >60% of the hospitals have established ECs. Sixty-five percent of the responders believe that the EC is an advisory committee and 31% an executive committee. Endoscopists believe that ECs have been of great help to their specialty in their country. CONCLUSIONS: The roles of the ECs are not clear to endoscopists and there is a need for education in this field.
BACKGROUND/AIM: Gastroenterologists are required to obtain informed consent before undertaking any endoscopic examination. Published data indicate that in practice there are many deficiencies in this process. The aim of this survey was to determine the quality of information given to patients before the endoscopic procedures in countries that are members of the European Society of Gastrointestinal Endoscopy (ESGE). METHODS: A structured questionnaire was sent to representatives of endoscopic societies that are members of ESGE regarding the quality of informed consent. RESULTS: The response rate was 59% (26/44). The endoscopist is responsible for giving the required information prior to written consent in only 23.1% (6/26) of the countries. Although information about the procedure is given to the patients in 96% of the responding countries, in only 77% is there sufficient time for the patients to ask questions about the nature of the procedure. In 15% (4/26) of the countries neither the diagnostic or therapeutic alternatives to endoscopy are discussed nor the potential complication rates. Finally, the procedure-related mortality is provided in only 23% (6/26) of countries. CONCLUSION: The procedure of obtaining informed consent for endoscopy varies considerably and may need reevaluation.
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In the hand, osteochondromas are rarely found. When encountered, these lesions occur at the metaphyseal region adjacent to the growth plate usually in patients with multiple hereditary exostosis. Our experience with solitary epiphyseal osteochondromas in the phalanges of seven children is reviewed. All patients presented a progressive angular deformity leading to limited function of the hand. Five patients had limited range of motion. Good restoration of motion and function was achieved by excision of the lesion and collateral ligament reconstruction. Early resection is recommended to correct and prevent further deformation in the growing skeleton of children.
OBJECTIVE: To determine if computed tomography of the patellofemoral joint has any advantage over standard radiologic techniques in the evaluation of recurrent patellar subluxation. DESIGN: A case series. SETTING: A tertiary children's hospital out-patient clinic. PARTICIPANTS: Forty consecutive adolescents with a clinical diagnosis of recurrent patellar subluxation (study group) and 14 volunteers with normal knees (control group). INTERVENTIONS: A standardized radiologic protocol, including axial views of the patella at 30 degrees of knee flexion, with and without external torsion of the tibia, and computed tomography (CT) of the patella at 15 degrees of knee flexion. MAIN OUTCOME MEASURES: The lateral patellofemoral angle on the axial views and on the CT scan and patellar centralization on the CT scan. RESULTS: In the control group, no radiologic evidence of recurrent patellar subluxation was found. In the study group, an abnormal lateral patellofemoral angle was found in 25% of axial views; this rate increased to 42% with external rotation and 86% on the CT scan. Patellar centralization was abnormal in 79% of cases. CONCLUSIONS: CT of the patellofemoral joint is more sensitive than standard radiographs for the diagnosis of recurrent patellar subluxation. The use of CT is recommended when standard radiographs appear normal.
OBJECTIVE: To determine if the presentation of scaphoid fractures in children has changed. DESIGN: Case study with a minimum follow-up of 1 year. SETTING: Outpatient orthopedic clinic in an urban pediatric hospital. PATIENTS: Twenty-one adolescents (mean age 13.9 years) with scaphoid fractures and an open distal radial growth plate. Fracture healing was assessed at 2-week intervals until union was achieved. INTERVENTIONS: Immobilization in a short-arm thumb spica cast. MAIN OUTCOME MEASURES: Fracture union as defined by the absence of pain and obliteration of the fracture line. Active and passive range of motion of wrist as measured with a goniometer. RESULTS: Only 2 of the 21 patients had avulsed fractures. Twelve fractures were located in the middle one-third of the scaphoid. All fractures healed, but two fractures were in a dorsiflexed position. All patients had full, painless range of wrist motion. No arthrosis was present. CONCLUSIONS: The presentation of scaphoid fractures in adolescents has changed over the years and now resembles the adult pattern. Malunited scaphoid fractures may be seen. Displaced fractures should be reduced.
To investigate the possible influence of gravity on daily variations of curve magnitude in adolescent idiopathic scoliosis, standardized anteroposterior standing radiographs of the spine were taken at 8:00 AM and repeated in the same conditions at 8:00 PM on the same day, 19 girls with idiopathic scoliosis, aged 10-16 years were included. The Cobb angle of the primary thoracic curve was measured blindly by four skilled orthopaedic surgeons. The mean interobserver variation in measuring Cobb angles on the 38 radiographs was 1.6 degrees. The average Cobb angle on morning radiographs was 60 degrees (range, 42-91 degrees) as compared to 65 degrees (range, 47-89 degrees) in the afternoon, a significant (P < 0.001) difference using a paired two-sided Student t test. It was concluded that there is a statistically and clinically significant daily increase of curve severity in moderate to severe idiopathic scoliosis.
Since treatment of a dislocated radial head is difficult in the growing child, we looked for risk factors associated with dislocated radial head in a group of patients with forearm osteochondromas. This is a retrospective study of 21 patients with a mean age of 7.7 years. We measured forearm bone length, size of the osteochondromas, ulnar variance at the wrist, radial articular angle and determined radial head localization. The severity of ulnar shortening was associated with radial head localization (p < 0.005). Ulnar shortening caused by ulnar osteochondromas larger than 0.20 of total ulnar length was associated with radial head dislocation (p < 0.001). Early treatment of ulnar shortening in this group might prevent the radial head from dislocating.
This study reports the effects of metoclopramide (10 mg i.v.) on intravascular esophageal variceal pressure in 12 patients with alcoholic cirrhosis. The esophageal variceal pressure was measured by the direct variceal puncture technique. Metoclopramide caused a reduction in the variceal pressure in 10 out of 12 patients; overall, there was a decrease from 21.5 +/- 5.0 mmHg to 14.0 +/- 3.4 mmHg (p < 0.001). In conclusion, intravenous metoclopramide, which increases lower esophageal sphincter pressure, significantly decreases intravascular variceal pressure in cirrhotic patients.
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To study the effect of hypokinesia on rats small intestine (jejunum and ileum) biopotentials it was first necessary to characterize it. Biopotentials were recorded by intracellular placed microelectrodes from oral and caudal segments of the small intestine. The character of rats small intestine biopotentials differs from that of other species (man, cat, rabbit, dog, e.a.), the slow waves (SW) being smaller and the frequency of basal electrical rhythm higher (31.23 c/min orally and 24.50 caudally). Spike potentials are inscribed on the descending slope of SW but frequently delayed in each successive wave with a regular interval. Hypokinesia obtained by keeping rats in small cages for two weeks create only little changes in intestine biopotentials. The only clear difference was the increase of the slow waves amplitude. The other parameters were not specifically changed.
Lower esophageal sphincter (LES) pressure was measured in 7 cirrhotic patients with massive ascites, before and after paracentesis. The mean LES pressure was 19.8 +/- 2.2 SEM mm Hg before and 16.3 +/- 1.4 SEM mm Hg after paracentesis (p less than 0.05). It is concluded that cirrhotic patients with massive ascites are protected from reflux esophagitis by having an increased LES pressure.
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The influence of the pressure-probe diameter on the values of gastro-oesophageal sphincter pressure, pharyngo-oesophageal sphincter pressure, and peak peristaltic pressure in the oesophageal body was investigated in eight healthy subjects. A low-compliance perfused pressure-measuring unit was used for the recordings. Three different probes were made with external diameters of 1.5 mm, 3.5 mm, and 4.5 mm. Sphincter pressures were measured in the resting state, and peristaltic pressures were measured during wet swallows. The pressure in the sphincter regions was found to depend on the diameter of the probe, whereas the peak peristaltic pressure amplitudes were independent of the probes used. The need for standardization of manometry equipment is emphasized.
A series of tests, including gastro-oesophageal sphincter pressure measurement, short-term pH tests, and 15-hour overnight oesophageal pH recording were applied to 42 normal subjects and 214 patients with typical reflux symptoms. The results were compared by multivariate discriminant analysis. Sphincter pressure measurements misclassified 32%, stressed provocative manoeuvres 14-5%, and the best single discriminator from the overnight pH study was time below pH 5, which misclassified 13%. However, a combination of the number of reflux episodes in 15 hours with their mean duration reduced misclassification to 8-8%. Using this function, a boundary between normal and reflux can be drawn, and the degree of abnormality can be expressed visually as well as numerically.