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Biomedical subjects

C Steele

Publications and source records attributed to C Steele.

85 records · Page 5Linked to original sources
PubMed1979

Assessment of the quality of sitting and gait patterns in children with Down's syndrome.

Clinical work with children with Down's syndrome resulted in a suggestion of a relationship between the external rotation and abduction of their hips, their excessive hip mobility in sitting, and their wide-based gait. This relationship was examined using data from 104 questionnaires completed by the parents of children with Down's syndrome. The clinical and demographic findings consistently documented the unusual sitting patterns of these children. How children were placed in the sitting position significantly influenced subsequent come-to-sit patterns but did not appear to influence subsequent walking patterns. Longitudinal studies of sitting patterns, hip mobility and gait are recommended. Therapeutic implications are that body rotation should be incorporated into motor intervention programs for children with Down's syndrome.

Biomechanical Phenomena↗
PubMed1979

Stimulation of lymphocyte proliferation by non-lymphoid porcine tissue cells.

Cultured porcine non-lymphoid cells, characterized by biochemical and morphological criteria, were derived from different tissues of individuals typed by serological and mixed lymphocyte culture methods for gene products of the major histocompatibility complex. These cultured cells have been used as stimulators in mixed lymphocyte-tissue cell cultures in order to investigate (1) the magnitude, kinetics and dose-dependence of lymphocyte transformation caused by tissue cells compared with that caused by lymphocytes as stimulators; (2) the relationship between the expression of serologically detected Ia-like antigens by tissue cells and their ability to cause lymphocyte transformation; (3) the genetic control of stimulation by tissue cells and by lymphocytes and (4) the expression and genetic control of lymphocyte stimulatory properties restricted to tissue cells and absent from lymphocytes. It has been shown that some but not all kinds of tissue cells can stimulate allogeneic lymphocytes strongly and that the characteristics of such stimulation are similar to those observed in mixed lymphocyte cultures. Strong stimulation by tissue cells does not always correlate with the expression of serologically detectable Ia-like antigens, but appears to be controlled by the major histocompatibility complex. There is evidence that certain tissue cells possess lymphocyte stimulatory properties not shared by lymphocytes. Preliminary data suggest that such tissue cell specific stimulation is not controlled by the major histocompatibility complex, though more detailed genetic analysis is required.

Animals↗
PubMedDate not supplied

Rendezvous in Rhamu. Teaching and learning with traditional birth attendants in rural Kenya.

When Carol Steele came to Rhamu, Kenya, in 1983 as a Quaker, Peace, and Service volunteer, there was little or no contact or cooperation between the Government Health Center personnel and the traditional birth attendants of the surrounding villages. The two groups were worlds apart in thinking, attitudes, and practices. The government center was viewed as alien by the people, with nothing to offer them except emergency care. The health center personnel viewed the traditional birth attendants as uneducated, unskilled women, who jealously kept clients away from the professional obstetric care the clinic provided. It was Carol Steele's plan to bring these diverse groups together in a professional, trusting relationship. Her success in accomplishing this task is the theme of this article.

Anecdotes as Topic↗
PubMedDate not supplied

Major depression in Alzheimer's disease. An interaction between gender and family history.

Major depression afflicts from 15% to 31% of patients with Alzheimer's disease (AD). The charts of 137 patients with AD were reviewed to assess the association between several variables and the risk of developing major depression. Thirty-eight patients (28%) had major depression. A family history of mood disorder was associated with a significantly increased risk for major depression, but this was only true in women (relative of odds = 2.82,95 confidence interval from 1.19 to 6.69). There was no relationship between major depression and a personal history of depression, younger age at onset of AD, history of substance use disorder, institutionalization, and marital status. These results suggest that the relationship between family history and depression in AD is more complex than previously thought.

Alzheimer Disease↗
PubMedDate not supplied

Smoking cessation: a consensus statement with special reference to primary care.

Nicotine addiction is a serious medical condition that needs to be treated like any other chronic disease. Primary care must play a key role in smoking cessation and offering help should be a routine part of primary care practice. As the most frequent opportunity for intervention lies within primary care, GPs should ensure that they raise the issue of stopping smoking at least annually with their smoking patients. When the smoker is ready to stop, the initial personal involvement of the GP is likely to increase the chance of a successful quit attempt. Follow-up may be with another healthcare professional. The support of healthcare professionals for the smoker who is motivated to quit, combined with appropriate pharmacotherapy, can substantially increase the chances of a successful quit attempt. Secondary care staff should also make every effort to help people to stop smoking and should communicate effectively with primary care--opportunities during hospitalisation are frequently missed. Specialist smoking cessation clinics have an essential role in providing more intensive specialist treatment and the expertise to partner and support the primary care effort. Smoking cessation is one of the most cost-effective healthcare interventions that can be made.

Family Practice↗