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Biomedical subjects

C Stoutenbeek

Publications and source records attributed to C Stoutenbeek.

3 recordsLinked to original sources

A new hygroscopic condenser humidifier.

A new hygroscopic condenser humidifier for the mechanically ventilated patient has been tested. It functions as a heat and moisture exchange device (HME) with an additional hygroscopic sponge to minimize the water loss from the breathing circuit. A comparative in vitro study was undertaken with a conventional HME. The influence of tidal volume, inspiratory flow rate and minute volume on the relative humidity of the inspiratory gas and on the water loss was investigated. The new device provides adequate humidification within a broad scale of ventilatory settings. In a subsequent clinical test the hygroscopic condenser humidifier proved to be a simple and reliable way of humidification.

Humans↗

Effects of dexamethason on the early postoperative course after coronary artery bypass surgery.

The effects of dexamethason (DM) on the postoperative course of coronary artery bypass have been investigated in a double blind study. Twenty patients receiving dexamethason 1 mg/kg body weight intravenously (IV) before cardiopulmonary bypass are compared with a control group of 20 patients receiving placebo. In the treated group core temperature remained normal (maximum 37.6 +/- 0.5 degrees C) while in the control group the patients regularly developed fever (39.0 +/- 0.7 degrees C; p less than 0.01). In the DM-treated group a significantly higher blood pressure, and a lower incidence of rhythm disorders were found. There was a marked difference in the fluid requirements between the 2 groups. Without DM the fluid balance was 2,300 cc positive at the end of the study, in the treatment group this excess was only 1,000 cc (p less than 0.001). Dexamethason treatment also led to higher urine output (130 cc/hr, vs. 85 cc/hr). Although the arterial oxygen tension was higher in the treated group, no patient developed respiratory insufficiency in the control group. The post-pump syndrome is re-evaluated and possible mechanisms are discussed.

Blood Pressure↗

Differential lung ventilation with HFPPV.

A case of a 53 year old lady who developed a unilateral "white lung" of known etiology three weeks after injury is described. The clinical picture was suggestive of a pleural or extra-pleural hematoma, and she was operated upon twice. During the second thoracotomy it became evident that the lesion was in the lung parenchyma. The patient was treated with differential lung ventilation with application of a high continuous positive airway pressure, followed by high frequency positive pressure ventilation (HFPPV) of the diseased lung with low frequency continuous positive pressure ventilation of the other lung. This technique proved to be simple and successful.

Female↗