Patch testing with a dilution series of nickel sulfate.
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Biomedical subjects
Publications and source records attributed to C Szliska.
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27 patients with positive D3 reactions on patch testing to 3 mercury screening allergens were patch tested with 13 mercury patch test preparations, 6 inorganic and 7 organic, and amalgam 20% pet. The 13 patients (all women) showing positive reactions to 20% amalgam were then patch tested to reducing concentrations. 2 patients reacted down to 1%, 4 down to 2%, 4 down to 5%, 2 down to 10% and 1 only to 20%, a total of 10 of the 13 patients therefore reacting to the 5% concentration of amalgam. The appropriate patch test concentration of amalgam is discussed and the clinical significance and female preponderance of amalgam reactivity suggested as being worthy of further investigation.
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857 non-dermatologic patients were patch-tested with the Finn-Chamber-technique. The sequent testings under identical conditions were made after 3-12 months. Readings were done after 24, 72, 96 hours and later. During the first test-series we found 44 reactions to be positive, 20 remained identical during repetition-testings, 7 became negative and 36 positive reactions appeared. So reproducibility was 46% for the positive results of the first testing serie.