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Biomedical subjects

C T Bombeck

Publications and source records attributed to C T Bombeck.

At least 73 records · Page 4Linked to original sources

Vagotomy--a prospective, randomized study.

This is a report of a prospective randomized study of 3 operations for duodenal ulcer; parietal-cell vagotomy alone (without drainage), selective vagotomy with antrectomy, and truncal vagotomy with antrectomy. All patients in the study have been followed for a minimum of 1 yr and despite the small number of patients (total 23 in this report), there has been a statistically significant return of gastric secretory activity to preoperative levels in the parietal cell vagotomy group, while both other groups maintained decreased acid secretion at the 1-yr period. To date there has been one recurrent ulcer and one other suspected ulcer in the parietal cell vagotomy group, while both other groups have no ulcer recurrence even though morbidity has been higher (bile reflux gastritis, and so forth). This preliminary evaluation suggests strongly that extreme caution be used in applying parietal-cell vagotomy alone as a definite operation for duodenal ulcer, but because of the small number of patients involved no conclusions can be drawn at this time.

Duodenal Ulcer↗

Continuous positive airway pressure in the prophylaxis of the adult respiratory distress syndrome (ARDS).

Alternate patients believed to be at risk for developing ARDS were placed on CPAP for the first twenty-four hours post upper abdominal surgery. Ten of the 58 controls developed ARDS, requiring prolonged mechanical ventilation with a 30% mortality rate. Only one of the 59 CPAP patients developed evidence of ARDS. This patient, however, is believed to have had fluid overload, and responded quickly to diuretics and was extubated within two days. Thus, prophylactic CPAP has greatly decreased our postoperative morbidity and mortality related to respiratory causes.

Abdomen↗

Intraoperative esophagoscopy, gastroscopy, colonoscopy, and endoscopy of the small bowel.

Intraoperative endoscopy of the gastrointestinal tract is probably much more widely used than has been publicized in the recent literature. Application of this new tool to the surgical armamentarium depends only on the limits of the imagination of the operating surgeon and his endoscopist colleague, in most cases, the gastroenterologist. The operative maneuverability of current endoscopes make every portion of the gastrointestinal tract accessible to direct visualization without incision into it, both by the operating surgeon and by the endoscopist. For the full potential of this modality to be realized, the same sort of cooperation between gastrointestinal surgeon and gastroenterologist must be achieved as currently exists between cardiac surgeon and cardiologist and between transplant surgeon and nephrologist. Once this cooperation has been established, application of these tools to gastrointestinal diseases should become commonplace in gastrointestinal surgery.

Adolescent↗

Umbilical portogram in a case of Schistosomiasis japonicum.

The life cycle of shistosomes in their human host contributes to protean pathologic changes in many organs. One of these, pre-sinusoidal hepatic fibrosis in the case of S. Japonicum, was studied by an umbilical portogram during the work-up before haemofiltration. Intrahepatic portal block, with rapid tapering and marked tortuosity of portal branches as well as a very inhomogeneous and variable parenchymal pahse with poorly marginated underperfused areas and reversal of extrahepatic portal flow, was demonstrated.

Catheterization↗