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C T Hasselman

Publications and source records attributed to C T Hasselman.

7 recordsLinked to original sources
PubMed1998

A dynamic analysis of glenohumeral motion after simulated capsulolabral injury. A cadaver model.

We used a dynamic shoulder-testing apparatus and nine fresh-frozen, entire upper extremities from cadavera to evaluate the effects of varying degrees of capsulolabral injury on the kinematics of the glenohumeral joint during abduction in the scapular plane and external rotation. Joint kinematics were recorded with use of a six-degrees-of-freedom magnetic tracking device before and after the creation of each capsulolabral lesion in a progressive manner. Dislocation did not occur after simulation of a large Bankart lesion or even after sectioning of the anterior aspect of the joint capsule. However, division of the entire joint capsule (that is, both the anterior aspect and the posterior aspect) resulted in a significant increase (p < 0.05) in posterior translation during abduction in the scapular plane, and two of the nine shoulders dislocated posteriorly. External rotation of the abducted extremity produced no increase in anterior or posterior translation.

Aged↗
PubMed1997

The John Charnley Award. Inhibition of wear debris mediated osteolysis in a canine total hip arthroplasty model.

In this study the efficacy of an oral bisphosphonate therapy to inhibit wear debris mediated bone resorption was evaluated in a canine total hip replacement model. Adult canines were randomized to three groups (n = 8 each) with a right uncemented total hip replacement performed on each animal. Group I (control) received no particulate debris. In Groups II and III, a mixture of 1 x 10(9) particles were introduced into the proximal femoral gap intraoperatively. The particle mixture consisted of fabricated ultra high molecular weight polyethylene (mean 2.3 microns, 90% by number), titanium alloy (mean 3.1 microns, 5%), and cobalt chrome alloy (mean 0.8 micron, 5%). Group III canines additionally received oral drug therapy (5 mg once a day, alendronate sodium) which was begun on postoperative Day 7 and continued until the time of sacrifice. Postoperatively, all animals were allowed 24 weeks of full ambulation before euthanasia. Radiographs obtained preoperatively, postoperatively, and at time of sacrifice were evaluated for periprosthetic osteolysis. Interfacial tissues were examined histologically and placed in organ culture and the supernatants were assayed for prostaglandin E2 and interleukin-1. One animal receiving debris (Group II) suffered a periprosthetic fracture and was sacrificed from the study. Radiographically, one of eight Group I (control) and six of seven canines from Group II (debris) had periprosthetic radiolucencies with endosteal scalloping develop. In contrast, only one of eight animals from Group III (debris + alendronate) had periprosthetic radiolucencies develop. Whereas tissues from control animals were mostly fibrous and acellular, tissues from both experimental groups had significant macrophage infiltration. Levels of prostaglandin E2 and interleukin-1 were elevated significantly in periprosthetic tissues from both experimental groups compared with controls. Continuous administration of alendronate effectively inhibited bone lysis for the 24-week duration of the study. This is consistent with the literature indicating that alendronate is incorporated in the mineralizing matrix making it refractory to osteoclastic resorption. This report has significant clinical implications for controlling the most common cause of implant failure.

Alendronate↗
PubMed1996

Technique for generating submicrometer ultra high molecular weight polyethylene particles.

Ultra high molecular weight polyethylene wear debris is believed to have a major role in aseptic loosening of prosthetic joints. In order to study the cellular and host response to this and other such particulate debris, a source of fine ultra high molecular weight polyethylene debris is needed. We have described a technique to fracture the GUR 4150 primary ultra high molecular weight polyethylene grain, which reproducibly generated particles less than 1 micron in size. Furthermore, the particle morphology was similar to that of ultra high molecular weight polyethylene particles generated in vivo and retrieved from interfacial tissues. The fabricated polyethylene particles ranged from 0.1 to 33 microns in diameter, with a mean of 2.3 +/- 0.2 micron. Sixty percent of the particles were smaller than 1 micron and 90% were smaller than 7 microns. Using filtration and sedimentation, it is possible to acquire finer particle fractions. These particles are currently being used for biological response studies.

Microscopy, Electron, Scanning↗
PubMedDate not supplied

A threshold and continuum of injury during active stretch of rabbit skeletal muscle.

Previous studies of acute muscle injury with active stretch used cyclic stretching or stretching the muscle to complete muscle-tendon dissociation. This study tried to determine minimal force required for skeletal muscle injury with one active stretch to establish an injury "threshold." Tibialis anterior and extensor digitorum longus rabbit muscles were actively stretched at 10 cm/sec to 60%, 70%, 80%, or 90% of the force required to passively fail tibialis anterior and extensor digitorum longus muscles of the control (contralateral) limb. Maximal isometric contractile force, tensile properties, histology, and electromyography were measures of injury. Both muscles of the 60% group showed no abnormalities in maximal isometric contractile force, tensile properties, histology, or electromyographic activity; 70%, 80%, and 90% groups showed diminished maximal isometric contractile force, muscle fiber disruption, edema, hemorrhage, and decreased electromyographic maximal voltage amplitude. The 90% group also showed alterations in tensile properties at failure along with connective tissue damage. Injury site included fiber disruption both at the distal myotendinous junction and muscle belly, with injury noted initially at the distal myotendinous junction in the 70% group. Electromyographic studies showed maximal isometric contractile force and maximal voltage correlated well as indices of damage. This study shows that a threshold and continuum for active stretch-induced injury exist, with muscle fiber disruption occurring initially and connective tissue disruption occurring only with larger muscle displacements.

Analysis of Variance↗
PubMedDate not supplied

An explanation for various rectus femoris strain injuries using previously undescribed muscle architecture.

We performed cadaveric dissection of the rectus femoris muscle to correlate the various lesions of strain injury seen with imaging studies to the muscular anatomy. The proximal tendon is composed of a superficial, anterior portion from the direct head, and a deep intramuscular portion from the indirect head. The muscle fibers arising from the anterior superficial tendon of the direct head travel in a posterior and distal direction to insert on the posterior tendon of insertion, giving the proximal muscle a unipennate architecture. Muscle fibers from the intramuscular tendon of the indirect head originate on both the medial and lateral sides of the tendon and insert on the distal posterior tendon to create its bipennate structure. Three chronic strain injuries involving the midmuscle belly substance were explored grossly and microscopically. It appears that one type of acute strain injury occurs in the midmuscle belly with disruption of the muscle-tendon junction of the intramuscular tendon resulting in local hemorrhage and edema. More chronically, this hematoma organizes into a fatty, loose connective tissue encasement of the deep intramuscular proximal tendon. Serous fluid from the hematoma may remain within the connective tissue sheath, creating a pseudocyst with the deep intramuscular tendon of the indirect head at its center. The muscle's anatomy helps to explain a different rectus femoris strain injury.

Athletic Injuries↗
PubMedDate not supplied

Incomplete, intrasubstance strain injuries of the rectus femoris muscle.

Rectus femoris muscle strain injuries commonly occur at the distal muscle-tendon junction of the quadriceps tendon. However, we have recently recognized a pattern of strain injury that consists of an incomplete intrasubstance tear at the muscle-tendon junction formed by the deep tendon of the muscle's indirect head and those muscle fibers originating from this tendon. These injuries are found more proximally within the thigh than the "classic" distal rectus femoris muscle strain. We reviewed 10 athletes with these intrasubstance tears, all of whom had diagnostic imaging performed using computed tomography or magnetic resonance imaging or both. Two of these patients required surgical intervention. The mechanism of injury usually involved kicking or sprinting. All patients had chronic thigh pain or an anterior thigh mass or both. Physical examination revealed thigh asymmetry and a nontender to mildly tender intrasubstance muscle mass. Magnetic resonance imaging demonstrated abnormal signal intensity centered about the intramuscular tendon of the indirect head of the muscle. Surgical findings included a mass of fibrous scar and fatty tissue encasing the deep tendon. Surgical removal of this fibrous mass appears curative. We contrast this injury from distal strains of the rectus femoris muscle, as well as from soft tissue neoplasms.

Adolescent↗