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Biomedical subjects

C T Moran

Publications and source records attributed to C T Moran.

5 recordsLinked to original sources

Equine ocular pathology ascribed to Onchocerca cervicalis infection: a re-examination.

Eyes from 292 old (15-20 years) horses originating in the eastern, southeastern and midwestern United States were examined for the presence of Onchocerca cervicalis microfilariae (mf) and concurrently for anterior and posterior segment ocular pathological changes. One-hundred-fifty-three animals (52.4%) were positive for dermal mf (range 0.03-5,364/mg). Of these, 60 animals had anterior segment changes. An additional 58 animals with pathological changes had no dermal mf. Mf were recovered from the ocular tissues of 18% of animals (range 0.07-29/mg). All animals with ocular mf were positive for dermal mf. Lesions most frequently encountered were punctate scleral opacities (in 14.0% of horses--7.2% with mf), temporal scleral viteligo (in 11.6%--6.8% with mf) and uveitis (11.0% of horses--6.2% with mf). Few significant posterior segment changes were seen. These data suggest that no ocular pathological changes represent reliable indicators for the presence of O. cervicalis infection.

Animals↗

Changes in intraocular pressure during acute exercise.

The effect of vigorous physical activity on intraocular pressure has been well documented. Other studies have only focused on pretest and posttest measurements of intraocular pressure. This study presents a continuous evaluation of intraocular pressure during exercise and correlates changes in intraocular pressure with changes in heart rate through time. A total of 17 adult male and female subjects were submaximally tested on a bicycle ergometer using the Astrand-Rhyming protocol. The results of this test were used to design an individualized four-stage workload that would proportionally take each subject to 85% of a predicted maximum heart rate. During this test, intraocular pressure was measured at the end of each stage and through 15 min of recovery with an American Optical non-contact tonometer. A statistically significant decrease (p less than 0.05) in intraocular pressure was noted at the end of the fourth stage and during 1, 5, and 10 min of recovery; however, no trend was found to indicate a significant correlation between heart rate and intraocular pressure.

Adolescent↗

The Corneal EyeSys System: accuracy analysis and reproducibility of first-generation prototype.

The EyeSyS Corneal Topography System manufactured by EyeSys Laboratories, Inc., Houston, Tex utilizes a unique data-acquisition design to perform rapid, cost-effective quantitative photokeratoscopy. We evaluated a first-generation prototype system. Repeated testing with this prototype demonstrated an accuracy and reproducibility to within 0.25 D on spherical surfaces. Similar results were obtained in testing aspherical surfaces without refocusing. Data from preliminary clinical studies are displayed for the following corneal conditions: normal, keratoconus, post-keratoplasty, and post-keratoplasty with wound ectasia. Advantages of the EyeSys System include rapid data analysis and display, ease of operation, and compact table-top size.

Adult↗