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Biomedical subjects

C Taecholarn

Publications and source records attributed to C Taecholarn.

8 recordsLinked to original sources

Spontaneous closure of bony defect in a frontoethmoidal encephalomeningocele patient.

The frontoethmoidal encephalomeningocele (FEEM) is a congenital herniation of meninges and brain tissue through the skull bony defect at the foramen cecum. The size of the defect may vary from a few millimeters to many. Those patients with a small defect may not always require a risky operation during childhood. We report on an infant whose bony defect has closed spontaneously with definite clinical evidence. It is proved that the skull defect and brain herniation are able to heal naturally, and this affirms an existence of the abortive subtype of FEE. Conservative treatment may be considered in those with a small bony defect, and surgery can be considered later when it is required.

Child↗

Clinicopathological features predicting recurrence of intracranial meningiomas.

A series of 11 recurrent meningiomas was studied. Most lesions occurred in women. The youngest patient was 17 years old and the oldest was 73 years. The mean age was 44 years. Multifactorial risk factors were involved in the tumor regrowth including age of patients, location of tumors, adequacy of initial surgery, certain histopathological features and subtypes of tumors. Tumors in young adults tended to have a rapid interval of regrowth as well as a tendency of multiple recurrences. Brain invasion, extensive bone and muscle involvement, foci of necrosis and hemorrhage, high mitotic index, angioblastic and papillary patterns were common pathological risk factors. Additionally, recurrent tumors may retain their original pathological appearance or become more aggressive by showing marked cellular pleomorphism. Area of liposarcomatous component was encountered in one recurrent lesion.

Adolescent↗

Cerebellopontine angle meningiomas with primary otologic symptoms.

The majority of cerebellopontine angle (CPA) tumors are acoustic neuromas (AN). However, an intracranial meningioma may occur at this site and will produce symptoms similar to an AN. The most common presenting symptoms of CPA meningiomas are hearing loss, tinnitus, dizziness and dysequilibrium. It cannot be easily distinquished from an AN only on the history and physical examination. Even with an audiogram, evoked response audiometry (ERA) and vestibular function tests, it still cannot be distinquished. CT scan and MRI are helpful in differentiating these two tumors radiographically. In this article, we report two cases of CPA meningiomas which presented with otologic symptoms. The diagnosis and treatment of CPA meningioma is discussed.

Adult↗

One-stage extracranial repair and reconstruction for frontoethmoidal encephalomeningocele: a new simple technique.

Forty-five patients born with frontoethmoidal encephalomeningoceles were treated using the craniofacial technique of one-stage extracranial repair and reconstruction. The operation begins with a bicoronal scalp flap, involving frontonasosuperomedial orbital wall osteotomy, reduction of the interorbital distance by nasal bone segment removal, hernial sac amputation and dural repair, medial orbital wall mobilization, medial canthopexy, and rib augmentation rhinoplasty. The result was very satisfactory. This new method has undoubtedly contributed in a major way to the improved results in frontoethmoidal encephalomeningocele treatment. We believe that the main advantages of this technique are that it offers a simple procedure for simultaneous correction of both soft tissue and bony deformities. The direct and external access to the neck of the hernial sac renders more secure dural repair with almost negligible cerebrospinal fluid leakage and eventually none of the postoperative brain sequelae. The postoperative course is less eventful and requires a shorter hospital stay than previous procedures.

Adult↗

Symptomatic intraspinal genuine endodermal epithelial cyst.

An intraspinal cervicodorsal endodermal epithelial cyst occurred in a 20-year-old man who experienced sudden paraparesis at the age of 6 years and subsequently developed progressive sensory disturbances. The patient underwent repeated surgical explorations indicating that the lesion may be difficult to identify. The cyst wall consisted of the outer smooth muscle and connective tissue and the inner epithelium that produced mucin and mucopolysaccharide. The intimate association between the epithelium and smooth muscle makes the cyst wall strikingly like the wall of the digestive tract or the respiratory passage and supports the endodermal origin of the cyst which must be distinguished from the neuroepithelial cyst. The pathogenesis of the endodermal epithelial cyst is suggested to be related to congenital maldevelopment of the notochord and the primitive gut.

Adult↗

Primary phycomycosis of the brain in heroin addicts.

Two heroin addicts had fatal primary phycomycosis of the brain. The first case is unique. A 28-year-old man displayed unusual symptoms of unilateral hydrocephalus confirmed by both computed tomography (CT) scanning of the brain and craniotomy. The nature of the fungal granuloma was verified histopathologically. The second case, a 40-year-old man, possessed bilateral basal ganglionic lesions in which the CT scanning suggested abscesses. Postmortem examination confirmed the presence of phycomycotic abscesses. There was no evidence of systemic mycoses in both cases. Review of the clinical features of this fatal complication in drug abusers and narcotic addicts disclosed that hemiparesis and facial weakness are common. Brain or CT scan along with brain biopsy are necessary for rapid diagnosis and prompt treatment.

Adult↗

Management of lipomyelomeningoceles. Experience at the Hospital for Sick Children, Toronto.

Ninety-seven children with lipomyelomeningoceles were operated on at the Hospital for Sick Children between January, 1960, and December, 1982. The most common factor that caused these patients to seek help was the cosmetic effect of the mass on their back. However, 22 patients had urinary incontinence and 15 patients had a deformed or weak leg. Sixty of the 97 patients were female and 37 were male. The patients presented for treatment between 6 days and 18 1/2 years of age with a median age of 7 1/2 months. Fifty-six patients presented before the age of 6 months and 35 of these were perfectly normal at the time of presentation. On the other hand, of the 41 patients who were brought for treatment after the age of 6 months, only 12 were normal prior to surgery. When patients were appropriately treated at an early age, with their spinal cords untethered and their dura securely closed with a dural graft, then they remained unchanged neurologically or even improved. However, when treatment was delayed or not done appropriately then they were left with significant neurological sequelae. Lipomyelomeningoceles are serious lesions which without appropriate therapy can result in gross impairment of neurological function.

Adolescent↗