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C Tauchnitz

Publications and source records attributed to C Tauchnitz.

At least 37 records · Page 2Linked to original sources
PubMed1980

[Experiences with the Antibody-coated Bacteria Test in the diagnosis of urinary tract infections].

We examined 67 cases with significant bacteriuria for the presence of antibody-loaded bacteria which shall refer to an infection of the upper urinary tract. With the help of this method we could diagnose 43 of the 45 cases with acute and chronic pyelonephritis. Three of the 22 cases with a bacteriuria of other genesis proved as falsely positive. The antibody-coated-bacteria-test should be used as diagnostic remedy in infections of the urinary tract as well as for course controls and as screening test in the clinic.

Antibody-Coated Bacteria Test, Urinary↗
PubMed1980

[The present significance of infection medicine and the problem of clinical microbiology].

Despite the reduction of the number of contagious infectious diseases the bacterial infection still play a considerable role. Here endogenic infections by the normal flora of the own body stand in the foreground. As hospital or nosocomial infections they endanger the patient who is disturbed in his defense by the basic disease and/or iatrogenically, in which case opportunistic germs and polyresistant problem germs participate. By this the tasks of the infection medicine are considerably enlarged, which demands measures to its reconsilidation. Nowadays also the medical microbiology must more and more orientate itself to clinical than to purely epidemiological questions. The establishment of a clinical microbiology has become urgently necessary. The clinical disciplines should participate in the adequate discussions, in order to yield the best possible result. A 3-step-proposition is made for realisation.

Anti-Bacterial Agents↗
PubMed1979

[Therapy of bacterial endocarditis].

The successful treatment of bacterial endocarditis requires a close cooperation to a clinical microbiological laboratory. This performs blood cultures, estimation of sensitivity to the different antibiotics, if anyhow possible also quantitatively, and supervision of therapy by serum bactericidal tests. Synergistic combinations by adding one of the aminoglycosides bring the best chances for therapeutic success. Special advices are given in dependence of the numerous causative bacterial agents. Rare ones are sufficiently taken into consideration. If blood cultures remain negative, empiricial chemotherapy is recommended. Surgical treatment by operative replacement of the infected heart valves and insertion of prosthetic ones is indicated in uncontrolled infection, in severe heart failure caused by valve perforation, and in recurrent embolism. Early interventions have a much better prognosis. Special problems are connected to bacterial endocarditis in prosthetic valves. Bacterial endocarditis in drug addicts is of relatively good prognosis in spite of the frequent complications. Patients with suspicious or evident bacterial endocarditis should be transferred to centers owing sufficient diagnostic and therapeutic experiences.

Administration, Oral↗
PubMed1979

[Frequency of bacteriuria in the aged (author's transl)].

1125 inhabitants of 2 homes for aged people were tested for bacteriuria by dip slides. Increasing of age did not lead to higher frequency of bacteriuria, neither in women (n = 869), nor in men (n = 256). The persons were divided in the 4 decades of being 61--70, 71--80, 81--90, and 91--99 years old. The corresponding rates of bacteriuria (greater than or equal to 10(5) germs/ml) were 14.0, 15.0, 12.4, and 9.1%, respectively. The rate of reproducibility was 75.4%, indicating still smaller values in reality. The discrepancies to the much higher values reported in the literature may depend on the people tested: "normal persons" instead of hospital patients or patients' specimens having been sent to a microbiological laboratory.

Age Factors↗
PubMed1977

[Therapy of staphylococcal endocarditis].

It is reported on the therapy with antibiotics of 5 patients with staphylococcal endocarditis with linkomycin--streptomycin. 2 patients were cured, 2 patients died after disappearing of fever and clinically unequivocally controlled septicaemia of typical complications of ulcerous endocarditis. One patient continued fevering to the exitus letalis when negative blood cultures were present, whereby at post-mortem examination an encephalomalacia with fresh haemorrhage was found to be the cause.

Adolescent↗
PubMed1977

[Therapeutic results using combined antibiotic therapy in chronic carriers].

From 1969 to January 1976 82 chronic carriers underwent a sanitation treatment. This treatment consists in an antibiotic combination treatment with ampicillin and canamycin during 24 to 18 days, in which case possibly simultaneously the cholecystectomy is striven for. In chronic carriers of S. typhi in 37 cases the combined antibiotic-operative treatment led to the permanent success. In chronic carriers of S. paratyphi B 21 of 22 cases were present. In patients with condition after cholecystectomy in every case one failure was present. In purely conservative approach the coefficient of success was 50 and 78%.

Anti-Bacterial Agents↗
PubMed1977

[Antibacterial combination therapy].

Reasons for the use of antibacterial combinations are synergistic effects and delayed development of bacterial resistance. On the basis of numerous experiments in vitro the opinion is supported that a clinically useful synergism depends on the addition of an aminoglycoside, the second compound being either one of the penicillins or cephalosporins, or a polymyxin, or a bacteriostatic agent like tetracycline, macrolide, and lincomycine. The decrease of MBC and MIC values varies according to the species and strains of bacteria and in dependence on the components of antibiotic combinations. Combination therapy with antibacterial synergism is indicated in life-threatening infections and in order to suppress bacterial persistences. Combinations with antagonistic effects should be avoided. The use of multiple antibiotics for broader spectrum only is not supported.

Aminoglycosides↗
PubMed1976

[The cephalosporins and their clinical value].

Up to now cephalothin was the only parenteral and cephalexin the only oral cephalosporin for clinical use in the GDR. The paper deals with several newer cephalosporins. Of these cephazolin shows some advantages, especially in antibacterial activity and serum levels. There is no metabolization and a better local tolerability compared with cephalothin. Cephapirin has no and cephacetril only inessential advantages. The antibacterial activity of the also well tolerated cephradin is less than that of cephalothin. Certain favourable pharmacokinetic properties such as high lymph and tissue levels, related to serum levels, slight protein binding, high distribution volume and a better stability against beta-lactamases lead to a superiority over cephalothin and diminish the disadvantages compared with cephazolin. The oral form of cephradin very equals to cephalexin.

Abortion, Septic↗
PubMed1975

[Bacteriuria--findings in diabetics].

The frequency of bacteriuria in 2.058 unselected diabetics obtained with the help of microscopic slides was 9.67%. Here women (n=1,325) with 13.5% have an essentially higher share of constant bacteriuria (number of germs more than 10(5)/ml) than men (n=733) with 2.4%. In very old men older than 75 years a clear increase to 14.6% could be proved. A relation between duration of diabetes and frequency of bacteriuria could not be ascertained. On the other hand there existed a dependence on the form of therapy of diabetes. A constant bacteriuria was present in dietetically led diabetics at 7.3%, in those persons treated with oral antidiabetics at 10.2%, in diabetics treated with insulin at 13.8%. The slide culture is clearly superior to the hitherto still used bacteriological and biochemical methods and is recommended particularly for screening tests.

Administration, Oral↗