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C Teplitz

Publications and source records attributed to C Teplitz.

30 records · Page 2Linked to original sources
PubMed1980

Evaluation of methylene blue and squamous epithelial cells as oropharyngeal markers: a means of identifying oropharyngeal contamination during transtracheal aspiration.

The usefulness of 1% methylene blue (MB) and squamous epithelial cells as oropharyngeal markers in transtracheal aspiration was prospectively evaluated. In vitro studies showed that failure to detect MB by spectrophotometry ruled out contamination by greater than 0.05 microliters of oropharyngeal secretions and that visual inspection was almost as sensitive as spectrophotometry. Even minute contamination could be ruled out if greater than 5 x 10(4) organisms were found by culture of Gram-stained smear in a specimen that was MB-negative by spectrophotometry. In specimens of transtracheal aspirate obtained from 10 bronchitic patients, quantitative bacteriology ruled out even minute contamination in nine. Cytologic-morphometric examination revealed that 70% of both sterile and colonized specimens of transtracheal aspirate contained squamous epithelial cells that were indistinguishable, except by electron microscopy, from buccal mucosal cells. MB is a useful marker for identification of oropharyngeal contamination during transtracheal aspiration, and traditional cytologic screening is misleading in conditions associated with tracheobronchial squamous metaplasia.

Biopsy, Needle↗
PubMed1978

Occupational lung disease.

Occupational lung diseases can be conveniently classified into disorders of the airways, the alveoli, and the lung interstitium. Diseases of each category have a distinct clinical and pathologic presentation despite diverse causes.

Asthma↗
PubMed1976

The core pathobiology and integrated medical science of adult acute respiratory insufficiency.

The straightforward core pathobiologic facts needed for the clinician's basic understanding of the clinical course and pathophysiology of progressive acute respiratory insufficiency (ARI) seen in surgical practice are summarized in the opening paragraphs. The remainder of the article provides the detailed evidence for elucidating the morphogenesis, i.e., the sequence of pathologic events, which determines the natural and the therapeutically altered clinicopathophysiologic courses of ARI. The attempt is to integrate observations concerning altered structure, cell biology, pathophysiology, physiologic function test data, bioengineering principles, clinical course, therapeutic management, and historical aspects of the disease process, into a detailed multidisciplinary but comprehensive explanation of this very complex, difficult disease process.

Airway Resistance↗
PubMedDate not supplied

Cervical smears prepared by an automated device versus the conventional method. A comparative analysis.

An automated, fluid-based method for the preparation of cervical Papanicolaou smears/slides was compared to the conventional Papanicolaou smear (CPS) method used for the screening of neoplasia. We determined diagnostic agreement and sources of error for diagnostic disagreement. For 665 patients, one cervical sample was collected to make one CPS. The collection devices, a wooden Ayre spatula and endocervical brush, were rinsed into a vial with fluid medium to be processed in the automated device. All slides were distributed among five cytotechnologists in a blind fashion. Exact diagnostic agreement was 94.6%. The results were not statistically significant (P > or = .70, McNemar's test) but were clinically important, as evidenced by the detection of low grade lesions (LGL), during initial screening, on three slides prepared by the automated device but not on their matched-pair CPSs (0.5% of all specimens). After reevaluation, the three matched CPSs demonstrated LGL. Sources of diagnostic error on the CPSs were: air-drying artifact, obscuring blood/inflammation, crowding/overlapping of cells and/or absence of diagnostic cells. The only source of error in the automated-method smears was absence of diagnostic cells.

Adolescent↗