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C Tesche

Publications and source records attributed to C Tesche.

4 recordsLinked to original sources

Evidence for somatosensory evoked responses in human temporal lobe.

Processing of somatosensory input in rhesus monkey is known to involve unimodal and polymodal association cortex within the the first superior temporal sulcus (STS) of the temporal lobe. The present study provides evidence for the activation of homologous structures in normal human subjects. Neuromagnetic evoked responses to intermittent unilateral median nerves stimulation were generated within the temporal lobe at 72-96 ms, with responses in the contralateral hemisphere leading those in ipsilateral cortex by 18 ms. The latency of these responses suggests that somatosensory information is available for integration with input from other sensory modalities in temporal cortex quite early in the processing stage.

Adult↗

Independence of steady-state 40-Hz response and spontaneous 10-Hz activity in the human auditory cortex.

We recorded neuromagnetic signals from 5 subjects with a 24-channel planar SQUID gradiometer. Our aim was to search for any relationship between the 40-Hz steady-state responses and the spontaneous 10-Hz activity in the auditory cortex. Source strengths and locations of spontaneous activity were determined from spectral components of the data, and sources within the auditory cortex were determined by restricting the source location to a neighborhood of the auditory evoked response to single clicks. The characteristics of the 40-Hz steady-state responses were not simply related to those of the spontaneous 10-Hz activity, even within subjects, suggesting that these two oscillatory phenomena have independent generators.

Acoustic Stimulation↗

A comparison of the localization of spontaneous neuromagnetic activity in the frequency and time domains.

We investigated the localization of current sources for spontaneous magnetoencephalographic data in the frequency and time domains. The two analysis techniques yielded complementary information about the underlying neuronal generators. Phase-coherent sources for occipital 10 Hz alpha band activity were identified in the frequency domain from the dependence of the equivalent current dipole strengths on the phase of the Fourier transform. Source localization in both the frequency and time domains was used to analyze data containing interictal spike and slow-wave activity. Predominantly 2-6 Hz spectral components localized in the frequency domain were found within an 8 cm3 volume centered at the time-domain source location of the spike. In general, the characteristics of the noise sources in magnetoencephalographic systems favor the use of frequency-domain analysis for rhythmic spontaneous activity.

Brain↗