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C Thacher

Publications and source records attributed to C Thacher.

9 recordsLinked to original sources
PubMed1991

Case report 673: Telangiectic osteogenic sarcoma.

A case is presented of a telangiectatic osteogenic sarcoma involving the left third metatarsal of a 4-year-old male Great Dane dog. Radiographs revealed a diaphyseal, expanding, lytic lesion with minimal intralesional sclerosis and a sclerotic rim in the proximal portion. The lesion contained a large amount of blood. The biopsy specimens consisted of spaces which were outlined by fibrous osteoid or granulation tissue. There were islands of multinuclear giant cells and/or fibrous osteoid tissue. A diagnosis of aneurysmal bone cyst was made. The lesion was treated by curettage and insertion of cancellous bone graft but was progressive 10 weeks after treatment. The lesion was further curetted, and these biopsy specimens consisted of aneurysmally dilated spaces and areas of anaplastic sarcomatous cells with mitotic figures and osteoid production, characteristic of telangiectatic osteogenic sarcoma. The dog was euthanized as the owner requested; an autopsy was not performed.

Animals↗
PubMed1990

Case report 622. Multiple cartilaginous exostoses.

The case is presented of multiple cartilaginous exostoses involving the right and left metatarsals and phalanges, left scapula, ends of several distal ribs, and the spinous processes of several thoracic and lumbar vertebrae in a 3-month-old female Scottish terrier dog. Radiographical studies showed circumscribed expansile lesions in the affected bones. The dog developed neurological deficits 3 weeks later. Myelography displayed extradural compression of the opaque column at several thoracolumbar vertebrae. The biopsy specimen from an affected phalanx consisted of trabecular bone and hemopoietic tissue covered by a thin cap of hyaline cartilage. The dog was euthanized due to the poor prognosis. At autopsy, the surface of the affected bones was covered by a bluish-white, smooth, undulating cartilage cap. Histopathologically, the cartilaginous cap consisted of hyaline cartilage without a reserve zone, and abnormal endochondral ossification. The hereditary nature and the malignant transformation of multiple cartilaginous exostoses in the dog have been considered.

Animals↗
PubMed1985

Osteosarcoma of the patella in a dog.

Osteosarcoma of the patella was diagnosed by biopsy in a 9-year-old, male dog of mixed breeding. The dog was originally examined because of intermittent lameness of the left hindlimb; there were minimal palpable abnormalities of the stifle. After the diagnosis, the owner refused further treatment for the dog. The dog was reexamined 13 months later because of a marked swelling of the stifle. The dog was euthanatized and necropsy findings confirmed the diagnosis.

Animals↗
PubMedDate not supplied

Neuroanatomic and pathophysiologic aspects of intervertebral disc disease in the dog.

A sound understanding of anatomy and the pathophysiology of disease is important in all branches of medicine, but nowhere is it more critical to success than in the medical and surgical management of intervertebral disc disease. Due to the remote location and unforgiving nature of the spinal cord, the veterinary surgeon must possess an intimate working knowledge of the surgical anatomy of the vertebrae, ligaments and joints of the spine, intervertebral discs, spinal cord, and spinal nerves. In addition, proper localization of spinal cord lesions during the neurological evaluation requires awareness of the functional neuroanatomy of the upper and lower motor motor neurons, the sensory systems and tracts, and the reflex arcs. Knowledge of the pathophysiology the intervertebral disc degeneration and the response of the spinal cord to disc extrusions are also important in the overall understanding of the disease and enhances proper decision making for its management. This chapter reviews the portions of the gross and functional neuroanatomy and the pathophysiology of the intervertebral disc and the spinal cord that are pertinent to the dog with intervertebral disc disease. Emphasis is placed on concepts that are critical for the veterinary surgeon who is involved in the surgical management of the disc patient.

Animals↗
PubMedDate not supplied

Problems with owner communications.

This chapter deals with communication problems between the veterinary surgeon and the owners of animals undergoing treatment for intervertebral disc disease, an area that has often been neglected in other works that usually deal exclusively with pathophysiology, diagnosis, and treatment. Neurologic disease can be a confusing subject, especially for the untrained owner of an afflicted animal and many areas of potential confusion between the veterinarian and the owner can occur. Potential problems may arise during the discussion of the medical history, interpretation of the neurologic examination, explanation of differential diagnostic and treatment alternatives, and description of the operative and postoperative phases. Each of these areas is discussed relative to the veterinarian's interaction with the owner of the animal patient.

Animals↗