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Biomedical subjects

C Thierfelder

Publications and source records attributed to C Thierfelder.

18 recordsLinked to original sources
PubMed2004

Contributions of sensory input, auditory search and verbal comprehension to cortical activity during speech processing.

We studied eight normal subjects in an fMRI experiment where they listened to natural speech sentences and to matched simple or complex speech envelope noises. Neither of the noises (simple or complex) were understood initially, but after the corresponding natural speech sentences had been heard, comprehension was close to perfect for the complex but still absent for the simple speech envelope noises. This setting thus involved identical stimuli that were understood or not and permitted to identify (i) a neural substrate of speech comprehension unconfounded by stimulus acoustic properties (common to natural speech and complex noises), (ii) putative correlates of auditory search for phonetic cues in noisy stimuli (common to simple and complex noises once the matching natural speech had been heard) and (iii) the cortical regions where speech comprehension and auditory search interact. We found correlates of speech comprehension in bilateral medial (BA21) and inferior (BA38 and BA38/21) temporal regions, whereas acoustic feature processing occurred in more dorsal temporal regions. The left posterior superior temporal cortex (Wernicke's area) responded to the acoustic complexity of the stimuli but was additionally sensitive to auditory search and speech comprehension. Attention was associated with recruitment of the dorsal part of Broca's area (BA44) and interaction of auditory attention and comprehension occurred in bilateral insulae, the anterior cingulate and the right medial frontal cortex. In combination, these results delineate a neuroanatomical framework for the functional components at work during natural speech processing, i.e. when comprehension results from concurrent acoustic processing and effortful auditory search.

Acoustic Stimulation↗
PubMed2003

[Immigrants with female circumcision in Switzerland: background information and recommendations for medical practice].

Due to increasing international migration Switzerland hosts women who have undergone female genital mutilation. Complications of female genital mutilation call for a comprehensive medically, socially and culturally adapted care. Health care providers in Switzerland are not adequately prepared to meet the specific needs of the women concerned, particularly because they are rarely exposed and have no national guidelines to rely on. This article based on qualitative research provides recommendations with the aim to improve the care for concerned African immigrant women in the Swiss health care system.

Adolescent↗
PubMed1991

Successful management of aortoesophageal fistula due to thoracic aortic aneurysm.

Aortoesophageal fistulas due to atherosclerotic thoracic aneurysms are usually fatal, with few reported survivors. We report an aortoesophageal fistula managed successfully in one stage by resection and replacement of the aortic aneurysm with a prosthetic graft and total esophageal resection. Immediate esophageal reconstruction was attained using orthotopic gastric interposition with omentopexy around the prosthetic aortic graft.

Aged↗
PubMed1991

[The ceramic system In-Ceram in the prosthetic dentistry--clinical and experimental results].

The ceramic system In-Ceram is a metal-free method to manufacture ceramic crowns and bridges. The metal framework is replaced by a sintered, glass infiltrated aluminium oxide substructure of high strength. Due to improved material properties the implementation of ceramic dental restorations allows a wider range of application. The paper presents own clinical experiences as well as recommendations concerning the dimensions of the aluminium oxide substructure.

Aluminum Oxide↗
PubMed1991

[Reexamination of cantilever bridges-a cross-section study].

In the present study reexaminations of 28 cantilever bridges and 26 conventional bridges were carried out. The aim was to evaluate the periodontal conditions and to give recommendations for use. Parameters were PI, GI, tooth mobility, pocket depth, gingival recession and BOP. Deducing from the results, which were statistical analysed, we recommend the cantilever bridges by right using. Special attention should be directed to antagonistical dentition.

Analysis of Variance↗
PubMed1991

[Investigations on secondary emission of metallic implant materials Ti and Ta following radiation].

Two implant materials, titanium and tantalum, were investigated for their electron emission in response to therapeutic tumor irradiation and were compared, in this context, to a substance equivalent to bone. The reaction of titanium was found to be similar to that of bone, whereas substantive increase in radiation was caused by tantalum which, consequently, should be removed from the radiation field.

Bone and Bones↗
PubMed1979

[The blood supply of the single tooth and its functional change caused by prosthetic therapy].

The author presents two functional diagnostic procedures for determining the blood supply to the individual tooth. Due to its methodical and instrumental prerequisites, it is not likely that intravital angiography will be developed into a procedure suited for stomatological practice. On the contrary, the nuclear-medical method for determining the microcirculation will become practice-relevant after technical improvement.

Angiography↗