PubMed Health⌕ Search

Biomedical subjects

C Urwin

Publications and source records attributed to C Urwin.

5 recordsLinked to original sources
PubMed1976

An evaluation of the mutagenicity of the cutting oil preservative Grotan BK.

The micronucleus test in rats was used to investigate the mutagenic potential of Grotan BK, a preserving agent used in industrial cutting oils. The test compound was administered either by intragastric intubation, dermal application or subcutaneous injection. CFHB (Wistar) rats were given two equal dosages separated by 24 h to provide total dosages of 15,60,240 or 960 mg/kg. In addition, as a positive control, benzidine at a total dosage of 409.6 mg/kg was administered similarly by the dermal and subcutaneous routes. Bone marrow preparations were screened for the presence of micronucleated cells in 2000 polychromatic erythrocytes. No increase in the incidence of micronucleated erythrocytes was observed for any group given Grotan BK by any of the three administration routes, or at any dose level. Benzidine induced high incidences of microcucleated erythrocytes following both dermal application and subcutaneous injection.

Animals↗
PubMed1976

"Play mobile" for blind infants.

The "Play Mobile" has been designed to help develop cognitive and motor skills in blind infants. It consists of an expandable metal rod which fits varying widths of cot, play-pen or doorway. Two hollow, ridged tubes are attached to the rod by springs, and from these are suspended four interchangeable objects which vary in shape and texture. The function of the "Play Mobile" is to provide a stimulating environment for the infant and to encourage him to expolre and to learn from the different properties and structures in his environmetn.

Blindness↗