PubMed Health⌕ Search

Biomedical subjects

C Utech

Publications and source records attributed to C Utech.

At least 19 recordsLinked to original sources

[Results of nuclear magnetic resonance tomography studies in endocrine orbitopathy].

Magnetic resonance imaging (T1- and T2-weighted) was performed in 65 patients with Graves' disease. In addition, T2 relaxation times of each ocular muscle were measured. Of the muscles thus studied, 54.8% showed a thickening in coronary tomograms. An interaction between the optic nerve and the thickened ocular muscles at the apex of the orbit was suspected in 30.1%. It could not be confirmed that the thickening of the muscles and the T2 value were related. However, there was a high correlation between the rise in intraocular pressure and the T2 relaxation time. These results imply that the T2 relaxation time is extremely useful in interpreting the activity of Graves' disease and provide a diagnostic tool of prognostic value in monitoring and treating this disease.

Adolescent↗

[Gaze-fixation tonometry or tonography in endocrine ophthalmopathy].

In patients with Graves' ophthalmopathy there is often a rise in intraocular pressure (dIOP) in changing from straight-ahead gaze to upgaze. If dIOP is measured using the applanation tonometer of the slitlamp, mistakes occur in pressure recording. In order to check these mistakes the authors compared tonometric with tonographic records of dIOP in 90 eyes of 45 patients. It was found that tonographic values were twice as high as tonometric values. Therefore, tonography furnishes more information about the activity of Graves' disease than tonometry; the errors of measurement associated with tonometry are also avoided.

Fixation, Ocular↗

Ciamexon-treatment in endocrine ophthalmopathy.

In severe cases of e.o. IV to VI combined treatment with Cyclosporin A and corticosteroids is most effective whereas Ciamixon alone appears to be less effective. Patients who received Ciamexon some time after termination of Cyclosporin A treatment showed slight ophthalmological improvement or stabilization of the status (judged after short time of therapy). Patients with e.o. III (IV), treated ineffectively with only corticosteroids before, showed a tendency of improvement under Ciamexon treatment.

Adjuvants, Immunologic↗

[Qualification and quality control in sonography].

On the basis of guidelines issued by the Kassenärztliche Vereingung Hessen, some criteria for the application of sonographic examinations are presented. Minimal requirements for sonographic equipment in certain specialties are mentioned, and it is pointed out how not only case history and clinical examination but also one's own sonographic evidence are important for a accurate sonographic diagnosis.

Abdomen↗

[Skeletal manifestations of generalized mastocytosis in the skeletal scintigram compared with roentgen findings].

Bone scans and skeletal x-rays of eight patients with systemic mastocytosis were reviewed. Mast cell infiltration of bone marrow had been proven histologically in every patient. Bone scan and roentgenographic findings are not specific for the disease and do not correlate well in some patients. A generalized increase of uptake was noted in two patients, a generalized decrease of skeletal activity with poor delineation of bony structures was observed in others. A circumscribed increase of activity was observed in some patients, only one patient had a normal bone scan. Roentgenographic examination revealed diffuse sclerosis of trabecular bone in three patients, osteoporosis with collapse of multiple vertebral bodies in three patients, and no abnormalities in two patients.

Adult↗

Treatment of severe Graves' ophthalmopathy with cyclosporin A.

Ten patients with severe Graves' ophthalmopathy, resistant to other therapeutic regimens were treated with cyclosporin A (CyA) over a period of 6 months. Clinically, 9 patients improved, 2 of them only after addition of corticosteroids. Intra-ocular tension on upward gaze decreased in all of these 9 patients (P less than 0.01). In 6 patients there was a significant decrease in eye muscle thickness under the treatment (P less than 0.05) as determined by computerized tomography. Side effects (e.g., paraesthesia, proteinuria) which were observed under higher doses of CyA, disappeared after lowering the dose. In only one out of 3 patients with hypertension an antihypertensive medication became necessary. CyA appears to be a valuable drug for treatment of severe Graves' ophthalmopathy when previous therapeutic regimens turned out to be unsuccessful.

Antibodies↗

[Sonographic localization of parathyroid adenomas in hyperparathyroidism].

The diagnostic efficacy of sonography for localisation of adenomas of the parathyroid glands in the neck region was investigated in 13 patients with hypercalcaemia and increased serum parathormone levels. Solitary parathyroid adenoma was demonstrated in all patients. The diagnosis was confirmed by surgery in 12 patients. In one patient, adenoma of the parathyroid can be assumed due to sonographically demonstrated increase in size and increase of serum parathormone. Adenomas of the parathyroid are characterised sonographically by typical dorsal position at the posterior surface of the thyroid, by echo-paucity and echo-density of the "capsular structure" around the adenomas. Sonography is suitable as screening method in hypercalcaemia and in increased parathormone serum levels for preoperative localisation of parathyroid adenomas.

Adenoma↗