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C Vázquez-Escobosa

Publications and source records attributed to C Vázquez-Escobosa.

14 recordsLinked to original sources
PubMed1983

Circulating immune complexes in hypertensive disease of pregnancy.

Circulating immune complexes in the blood of patients with hypertensive diseases of pregnancy were investigated. Sixty women with pregnancies between 30 and 40 weeks were studied. Of these patients, 22 were normal, 18 developed preeclampsia, 2 developed eclampsia, 14 had essential hypertension, and four had hypertension of renal origin. Circulating immune complexes were determined by the method of phagocytosis and immunofluorescence. They were found only in patients with preeclampsia or eclampsia, and were constituted of IgG and C3. It is suggested that the detection of circulating immune complexes by this method can be useful in the differential diagnosis of preeclampsia from other hypertensive diseases of pregnancy.

Adult↗
PubMed1981

Levamisole does not produce chromosome fractures.

Levamisole is a drug chemically related to metronidazole. Metronidazole produces chromosome alterations in animals and humans. The aim of this work was to investigate if levamisole could produce chromosome fractures in mice. Levamisole and metronidazole were injected daily during five days, subcutaneously, at pharmacological doses of 2.5 and 6.2 microgram per g of body weight respectively to BALB/c mice. Three injected and control mice were sacrificed each day and chromosome studies were performed with hematopoietic sternum cells. In control mice, forty acchrocentric chromosomes were found without fractures. Metronidazole-injected mice showed increasing percentages of chromosome fractures from the first to the fifth day of the study: 0, 1.46, 1.72, 7.70 and 9.10. Levamisole-injected mice did not show chromosome fractures at that time.

Animals↗