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Biomedical subjects

C Vance

Publications and source records attributed to C Vance.

14 recordsLinked to original sources
PubMed1995

D-2-hydroxyglutaric aciduria.

Hydroxyglutaric aciduria is detected by gas chromatographic-mass spectrometric analysis, and the D and L forms are quantified by chemical ionization with deuterated internal standards. Patients have recently been described who accumulate the D form, and they appear to be quite different from those with the more common L form. Experience is reported with three patients and an animal model with D-2-hydroxyglutaric aciduria. The phenotype appears to include mental retardation, macrocephaly, hypotonia, seizures, and involuntary movements, although neurologic and systemic manifestations of the disorder varied considerably between individual patients, even within the same family.

Animals↗
PubMed1992

Managing the politics of the workplace.

The workplace--usually the hospital--is the laboratory for the new nurse's first year of practice. Lacking experience, the neophyte will need to learn organizational savvy and judgment and gain clinical experience with the help of a preceptor-mentor. Properly managing the first year of professional practice in the workplace will result in career success and satisfaction.

Conflict, Psychological↗
PubMed1991

The effect of valproic acid on plasma carnitine levels.

Plasma total, free, and acyl carnitine levels were determined in four groups of children: (1) those treated with valproic acid as monotherapy (n = 43), (2) those treated with valproic acid plus other antiepileptics as polytherapy (n = 91), (3) those treated with other antiepileptic drugs alone (n = 43), and (4) normal patients (n = 89). The mean free carnitine level was significantly lower in both the valproic acid monotherapy (29.9 mumol/L) and polytherapy (21.4 mumol/L) groups compared with normal subjects (36.8 mumol/L); it was also significantly lower than that in patients treated with other antiepileptic drugs (36.7 mumol/L). Comparison of valproic acid polytherapy and monotherapy yielded significantly lower free carnitine levels in the polytherapy group. The ratios of acyl to free carnitine for monotherapy (0.41) and polytherapy (0.45) were significantly higher than that in the normal group (0.25). This study indicates that a general decrease in the carnitine pool should be anticipated in patients taking valproic acid polytherapy and, to a lesser degree, monotherapy. Carnitine levels in the group taking other drugs did not differ from normal.

Adolescent↗
PubMed1989

Human papillomavirus-16 DNA in a cutaneous invasive cancer.

A middle-aged man with a 20-year history of a warty lesion on his finger was diagnosed histologically as having an invasive carcinoma at that location. Molecular analysis of the lesion showed that human papillomavirus (HPV) DNA was present in this tumor. Under stringent hybridization conditions, only HPV-16 DNA, which is commonly associated with genital neoplasia or cutaneous bowenoid lesions, was detected. Two-dimensional gel electrophoresis revealed that various sections of the tumor contained mostly episomal viral DNA; but in one case, low levels of integrated HPV-16 DNA were detected as well.

Carcinoma, Squamous Cell↗
PubMed1989

Changing the public image of nursing: development of a community nurses network.

Gross, Frost, and Vance give new meaning to community health nursing. They describe a nursing network that engages in the processes of politics, power, and innovation to bring about community change while enhancing the status of the profession. The community project described here demonstrates to others the expertise and autonomy of professional nurses.

Community Health Nursing↗
PubMedDate not supplied

Enrollment management.

Attracting and retaining students in schools of nursing are of crucial importance to faculty. Although enrollment management functions are not part of the traditional faculty role, the authors describe how nursing faculty in a private liberal arts college instituted and implemented a successful enrollment management plan.

Advertising↗
PubMedDate not supplied

Is there a mentor in your career future?

Your new career in nursing holds limitless possibilities for you. Successful career planning and career development must inevitably include the presence of strong nurturing relationships. Whatever form these support relationships take--be it mentor-protege or peer-peer--they will play an increasingly important role in helping you develop as a competent, happy, successful, and confident professional. As members of the nursing profession, we have an edge on helping and being helped by each other. We have strong nurturing backgrounds. We have a deep concern for and sensitivity to human needs. We can help each other as mentors or peer colleagues. Finding mentors and other types of support connections along your career path is essential for "making it" in the professional work world. Each of us needs the gift of mentoring, both as recipient and as giver.

Education, Nursing, Continuing↗