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Biomedical subjects

C Venables

Publications and source records attributed to C Venables.

13 recordsLinked to original sources
PubMed1988

Endoscopy: its diagnostic role in dyspepsia.

Fibreoptic endoscopy is now recognised as the most reliable diagnostic technique for establishing the cause of upper gastro-intestinal symptoms. However, in the UK the demand for endoscopic diagnosis far outstrips our ability to meet it and in this article an attempt is made to define how one can limit this demand so that a high diagnostic yield can be anticipated.

Duodenal Diseases↗
PubMed1988

Duodenitis.

This article discusses the relationship between peptic ulcer and mucosal inflammation changes in the duodenum (duodenitis) in the light of experience in our centre and a review of recent literature. It is concluded that duodenitis is part of the duodenal ulcer diathesis but is rarely the cause of symptoms.

Adult↗
PubMedDate not supplied

Maedi-visna and sheep pulmonary adenomatosis: a study of concurrent infection.

The transmission of maedi-visna (MV) virus was studied within two groups of sheep, one of which was also affected with sheep pulmonary adenomatosis (SPA). Serological monitoring of sheep kept in contact with both groups indicated that MV virus replication occurred to a greater extent in the group with both diseases, three of five in-contact sheep being seropositive after 1 year's exposure compared with none of six held with MV-virus-only infected lambs.

Animals↗
PubMedDate not supplied

Clinical and immunological responses of ewes following vaccination with an experimental formalin-inactivated Chlamydia psittaci (ovis) vaccine and subsequent challenge with the live organism during pregnancy.

The protection afforded by an experimental, killed, adjuvanted vaccine derived from the A22 strain of Chlamydia psittaci (ovis) against ovine enzootic abortion was studied. The vaccine was used undiluted (group A), at a dilution of 10(-3) (group B) and at a dilution of 10(-6) (group C). A fourth control group (group D) was inoculated with all components of the vaccine except the chlamydial antigen. A group of rams (group R) was also vaccinated with the chlamydial antigen diluted to 10(-3). Animals were challenged 70 days after mating with the A22 strain of C. psittaci (ovis) and were studied throughout pregnancy and the subsequent lambing period. Their cell-mediated immune responses were examined using a skin test and their humoral immune responses were studied using an ELISA. Tests for excretion of chlamydiae in their faeces and genital tract during pregnancy and after parturition and in the faeces of their lambs were made. The reproductive performance of the ewes was assessed by calculating the average weight of lambs produced per ewe in each group. The experimental vaccine protected the ewes in groups A and B against challenge with C. psittaci (ovis) as none showed clinical signs of OEA or excreted chlamydiae. The average weight of lambs produced per ewe in both groups was greater than 4 kg. Both groups seroconverted after vaccination but not all of them were positive to the skin test. The experimental vaccine at 10(-6) dilution of antigen did not protect the ewes as three of 10 ewes displayed clinical OEA and excreted chlamydiae in the products of parturition.(ABSTRACT TRUNCATED AT 250 WORDS)

Abortion, Veterinary↗