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Biomedical subjects

C Veron

Publications and source records attributed to C Veron.

13 recordsLinked to original sources
PubMed1998

[Epithelioid sarcoma manifesting as chronic plantar arch ulceration].

BACKGROUND: Epitheloid sarcoma is an uncommon malignant soft tissue tumor observed in the distal extremities of young men. We report a case of long standing ulceration of the sole which was found to be an epithelioid sarcoma. CASE REPORT: A 78-year-old woman had an indolent ulceration of the left sole for several months. Physical examination disclosed a well demarcated 3-cm ulcerated lesion with a red center and flat edges. Skin sections confirmed the diagnosis of epithelioid sarcoma. Cells stained positively for anti-vimentin, anti-cytokeratin and anti-epithelial membrane antigen, but not for anti-S100 protein and anti-actin antibodies. Wide local excision was performed. DISCUSSION: Epithelioid sarcoma is an uncommon malignant tumor which apparently differentiates from mesenchymatous cells. It is usually observed in the distal extremities in young males, predominantly the hands and forearms. The tumor presents a firm, flesh-colored indolent nodule. Ulceration usually develops and involves the subcutis and deeper soft tissue, particularly fascial planes, aponeuroses and tendon sheaths. Treatment is wide surgical excision with or without radiotherapy. The case reported here on the sole of the foot in a 78-year-old women is unusual. Clinicians should be aware that the initial biopsy may not be contributive and that repeated biopsies may be necessary for positive diagnosis.

Aged↗
PubMed1997

[Implant rehabilitation of distal mandibular atrophy using a blade implant].

After a brief revision of the anatomy of the posterior mandible and its natural resorption pattern, the ramus plate-form implant would be the implant of choice for the rehabilitation of this region. This "site specific" implant is inserted on the top of the crest and superficially impacted within the residual alveolar bone at the distal segment of the horizontal branch and guided to climb parallel to the anterior aspect of the ascending ramus. Its form and specific dimensions are perfectly compatible with the frequently limited quantity of available bone above the nerve canal in patients with advanced atrophy of the posterior mandible. It provides a predictable abutment for the implant-supported or dento-implant-supported prostheses of the posterior mandible.

Alveolar Process↗
PubMed1994

[Towards a decrease of myocardial infarction in the Bas-Rhin region? Results of the 6 first years of the Strasbourg MONIC Register].

The Bas-Rhin MONICA Register shows trends in myocardial infarction and other acute ischemic events between 1984 and 1989. Coronary heart disease mortality decreased by 27% in men and 30% in women. Morbidity trends were less favourable. The annual event rate for total acute ischemic events remained stable. However, a decrease of 14% for myocardial infarction was seen in men, particularly in patients with a past history of coronary disease. Another positive point is that the 28-day mortality rate in recent infarctions decreased in men by 33% during the 5 year period.

Acute Disease↗
PubMed1989

Nickel, chromium, cobalt dental alloys and allergic reactions: an overview.

Possible correlations between allergic reactions and the significance of a dental prosthesis or restoration made from one or more of the metals nickel, cobalt and chromium are considered. Described clinical cases are reviewed. These allergic reactions may appear either locally as stomatitis or distantly in the form of general or local contact dermatitis.

Chromium Alloys↗
PubMed1989

[Non-precious metal dental alloys and allergy].

The fundamental basis of allergy, particularly in relation to contact allergy, is described, together with the importance and frequency of sensitization to nickel, chromium and cobalt in both the consultant and general population. 139 published cases of allergy to dental restorations containing these metals are reviewed involving 92 female and 47 male patients, 115 of whom recovered when the restorations were removed. The most frequent symptoms were local (99/139), particularly gingivitis and stomatitis, while general or remote symptoms occurred in 33 cases. This probably underestimates the true prevalence of the condition, because a large number of reported cases have not been due to their "current appearance". The influence of the occupational environment of the patient is described with special reference to dental technicians. The persistence of contact allergy to metals for which no desensitization is possible is also emphasised. The discussion includes experimental investigations and an appraisal of other methods of revealing hypersensitivity. Finally, some simple recommendations for prevention are made which are of value to practitioners.

Chromium Alloys↗
PubMed1986

[Dental amalgams and allergy].

After a short description of the fundamental basis of allergy, particularly in relation to contact allergy, the authors review the 41 published cases of allergy to dental amalgam consisting of 30 female and 11 male patients. 20 of these patients recovered on removal of the dental amalgam. The most frequent symptoms were of the remote cutaneous type (38/41 cases) while local symptoms, particularly gingivitis and stomatitis, occurred in 17 cases. These probably underestimate the true prevalence of the condition for several reported cases have not been published. The authors then go on to describe the sensitizing property of amalgam in relation to the occupational environment and the length of time that the amalgam has been in the mouth. Mercury is the most common sensitizing agent, but other metals, particularly cooper, zinc or silver could also be implicated. The authors attempted to explain the physio-pathological mechanism of sensitization via the cutaneous as well as the oral, digestive and respiratory tracts by describing the chelating properties of metals with cellular or tissue constituents. In the last chapter, the prevention and clinical treatment of sensitization to dental amalgams is described.

Adolescent↗
PubMed1984

[Gingival pigmentation caused by dental amalgam. An ultrastructural study].

The aim of this investigation is the ultrastructural analysis of biopsies of human gingiva pigmented by the metallic deposits from dental amalgam. The size, the nature and the distribution of the particles are studied by light and electron microscopy and by energy dispersive spectrometry (EDS). Fragments and particles of different size and composition are observed. No traces of mercury are detected in any examined samples. In contrast, very fine grains (0.01 to 0.05 microns in diameter) of a silver compound are observed to be preferentially bound to intracellular membranes and to extracellular structural components. Tissue modifications in the gingival epithelium as well as in the connective tissue can accompany the pigmentation phenomenon. The different metabolic pathways of the metals diffusing from the amalgams are discussed.

Biopsy↗
PubMed1983

Pathological effects of N-methyl-N'-nitro-N-nitrosoguanidine on oral mucosa in Wistar rats after transplacental exposure.

This study examined the effects of N-methyl-N'-nitro-N-nitrosoguanidine (M.N.N.G.) on the oral mucosa of Wistar rats. The rats were born from dams treated by i.p. injections of M.N.N.G. during gestation. Each pregnant rat of a first group received a total dose of 39.60 mg/kg of M.N.N.G. administered throughout the gestation period. Each pregnant rat of a second group received a total dose of 82.50 mg/kg of M.N.N.G. by i.p. injections during the first ten days of gestation. In the progeny of dams from both groups, the morphology of the gingiva was modified. The lingual gingiva from the lower jaw was most impaired. The epithelium always displayed hyperplasia: acanthosis, papillomatosis and hyperkeratosis. These results indicate a pathogenic effect of M.N.N.G. on lingual, mandibular gingiva. This effect was slight but permanent and irreversible. No carcinogenic effect was noticed on the oral mucosa. Similarities between the lesions described in this work and human epithelial dysfunction makes this experimental model interesting.

Animals↗
PubMed1980

[Not Available].

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France↗