Biomedical subjects
Publications and source records attributed to C Verougstraete.
Case report of a woman with the characteristics of dominant exudative vitreoretinopathy. These anomalies are however unilateral and the family study is not very contributive. A platelet aggregation study carried out on the patient and 3 family members is normal.
An analysis by fluorescein angiography of the first signs of retinopathy in 161 diabetic children showed that microaneurysm-like spot dilatations, microaneurysms, focal capillary dilatations, leakage, generalized capillary dilatations, retinal hemorrhages, areas of capillary non-perfusion and capillary remodelling, in decreasing order of frequency, were features of the onset of retinopathy. However, microaneurysm-like spot dilatations and both focal and generalized capillary dilatations were considered to be too subjective for use in further quantitative analysis. Retinopathy was not found in children less than 12 years of age and was detected only after at least 3 years of diabetes. The mean duration of diabetes before the occurrence of the first lesions in 118 affected eyes was 8.2 years. The mean age at which lesions occurred was 16.4 years. Although capillary non-perfusion was rarely an initial lesion, occurring after a longer duration of diabetes and at a later age than the other lesions, no significant difference could be found between the various types of lesions for either the patient's age at their onset or the duration of diabetes. The type of initial lesion was also unrelated to sex, age at the onset of diabetes, or metabolic control.
Acute arterial hypertension causes 3 types of fundus anomalies: hypertensive retinopathy, hypertensive choroidopathy and hypertensive optic neuropathy. Hypertensive retinopathy and optic neuropathy are characterised by retinal and optic disc capillary and precapillary occlusions, and a rupture of the inner hemato-retinal barrier resulting in retinal edema. Hypertensive choroidopathy is characterized by areas of choriocapillaris occlusion resulting in necrosis of the pigment epithelium which causes a rupture of the outer hemato-retinal barrier and retinal edema.
Venous occlusion causes retrograde intravascular hyperpression resulting in a rupture of the inner hematoretinal barrier and sometimes in capillary occlusions. The various clinical types of venous thrombosis which result from various degrees of intravascular hyperpression have different prognoses. The laser treatment of macular edema secondary to venous occlusion is recommended under certain conditions.
Retinal telangiectases have 3 main clinical forms: Leber-Coats disease, Adult Coats disease and parafoveal telangiectasia. Clinical characteristics, evolution and modes of treatment will be reviewed.
Retinal macroaneurysms cause visual symptoms either by hemorrhage, by exsudation or by arterial occlusion. Laser treatment shortens life duration of the macro-aneurysm and results in reabsorption of retinal edema. Direct coagulation of the macroaneurysm should be avoided so as not to enhance the risk of arterial occlusion.
We report a case of peripheral Toxocara granuloma in a young boy of 17. Of the 3 forms of ocular toxocariasis, macular granuloma, endophthalmitis and peripheral granuloma, the latter is the least common and is characterized by the retention of relatively good vision. A differential diagnosis was performed between an intraocular foreign body encapsulated in fibroglial tissue, toxoplasmic retinochoroiditis, retinoblastoma, intermediate uveitis and toxocariasis. Fluorescein angiography showed not only some neovascularizations at the level of the peripheral granuloma but also manifestations of inflammatory reactions at the level of the posterior pole, i.e. diffuse leakages from retinal capillaries and parietal staining of some venous segments. Among the various laboratory tests, the most significant are eosinophilia, IgE concentration and detection of specific antibodies in serum as well as in aqueous humour.
Explore the source record for details and available documents.
At the crossroads of the psychological and the somatic course, a symptom appears as a crisis for the patient (the child), his environment and the medical and paramedical staffs who are in contact with him. Starting concrete situations, this article describes what happens when the family is confronted with the reanimation of a child.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Acute disc swelling in type-I diabetic patients is a distinct syndrome that may be distinguished clinically, particularly from papilloedema due to increased intracranial pressure. This paper reports the first detailed case of this rare condition in which disc swelling seems to be associated with rapid improvement of metabolic control. We suggest that the pathogenesis of disc swelling is related to a local breakdown of the blood retinal barrier at the level of the optic nerve, resulting in an intense leakage. Compression of the optic nerves secondary to this vasculopathy appeared to be reversed by administration of dexamethazone. It is suggested that in diabetic patients with long-standing poor metabolic control, rapid conversion to good metabolic control could have this result. However further information is necessary to substantiate this relationship.
Explore the source record for details and available documents.
Explore the source record for details and available documents.