Renal transplantation under FK 506 in African-Americans: early experience.
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Biomedical subjects
Publications and source records attributed to C Vivas.
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Retrograde transurethral balloon dilatation (RTBD) of the prostate recently has been suggested as alternative therapy for patients with benign prostatic hyperplasia (BPH). Seven patients with documented functional urinary outlet obstruction at the level of the bladder neck or prostatic urethra underwent RTBD of prostate. Each patient had a classic diagnosis of abacterial chronic prostatitis or prostatodynia based on history, physical examination, and localization cultures. Prior to RTBD of prostate, patients underwent cystoscopy, voiding cystourethrogram, urodynamic and uroflow studies. RTBD of prostate was done as an outpatient procedure requiring intravenous sedation or general anesthesia. Dilation was performed with a 25-mm urethroplasty balloon catheter inflated at 3.5 atm of pressure for twenty minutes. Improvement in voiding symptomatology was noted in all patients and graded numerically (0-10 scale), with ten indicating normal voiding. Follow-up to date ranges from one to five months. This technique may have promise as a treatment option in patients with abacterial chronic prostatitis and prostatodynia.
A new method of transurethral drainage was used in 36 consecutive patients who underwent urethral reconstruction for repair of hypospadias and epispadias. The surgical procedures included 16 island flap urethroplasties, 15 distal urethral repairs with Mathieu's technique, 3 epispadias repairs and 2 urethroplasties with a modified Thiersch-Duplay technique. To accomplish urinary drainage in all cases a 7 or 10F silicone tube with multiple perforations was inserted proximal to the bladder neck and through the repair, and cut 2 mm. distal to the urethral meatus. The tube was secured to the meatus with loosely tied 4-zero polypropylene sutures and allowed to drain into a diaper. Satisfactory results were obtained in all patients. Complications included a small urethrocutaneous fistula in 6 children, a distal urethral stricture in 1 and severe bladder spasms in 2. The incidence of fistula formation did not appear to increase with this method of urinary drainage. Advantages of the method included a decreased hospital stay and minimal discomfort.
The effect of either chronic noise or water restriction on body weight gain and weight of several glands and organs has been studied in male Wistar rats. The results indicate that chronic noise does not affect the relative weight of glands and organs but it induces a slight decrease in body weight gain. Water restriction provokes a strong decrease in body weight gain and relative weight of the liver while it increases significantly the relative weight of other glands and organs as a likely consequence of the decrease in body mass. Chronic noise does not seems to be a strong stress and it markedly differs from water restriction which is not appropriate as a model of chronic stress.
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