Biomedical subjects

C W Cummings

Publications and source records attributed to C W Cummings.

95 records · Page 6Linked to original sources

PubMedDate not supplied

Immediate mandibular reconstruction: human experience with autogenous frozen mandibular grafts.

Autogenous mandibular grafts that have been cryosurgically devitalized and reimplanted have been studied in the canine. Initial investigations have lent impetus to further application in human cancer surgery. Six patients underwent immediate autogenous mandibular graft reconstruction. All failed because of intraoral complications and decreased vascularization in the midportion of the bone graft. None evidenced recurrence of tumor in bone, although two patient's grafts failed on the basis of tumor recurrence in the adjacent soft tissue.

Carcinoma, Squamous Cell↗

PubMedDate not supplied

The incidence of hypopharyngeal stenosis after surgery for laryngeal cancer.

Hypopharyngeal stenosis is a frequent complication of laryngectomy and radiotherapy in patients treated for carcinoma. In a retrospective study of patients treated in the University of Washington Affiliated Hospitals, hypopharyngeal stenosis was more frequent after laryngectomy with partial pharyngectomy than after laryngectomy alone and occurred more commonly in lesions of the pyriform fossa than in glottic tumors. Neck disease and inclusion of radical neck dissection were both significant factors in the development of hypopharyngeal stenosis. Recurrent tumor was significantly more prevalent in these patients.

Carcinoma, Squamous Cell↗

PubMedDate not supplied

Giant lymphoid hyperplasia presenting as a highly vascularized parapharyngeal mass.

Giant lymph node hyperplasia is a rare, benign tumor infrequently occurring in the head and neck. A 31-year-old woman with this disorder, present as a large submucosal parapharyngeal mass, is presented and the literature reviewed. Radiographic evidence of the extreme vascularity of this lesion was remarkable, emphasizing the value of arteriographic evaluation of masses located in this region. Preoperative embolization facilitated its complete resection, and follow-up examination has shown no evidence of recurrence, which is commonly the course of the disease elsewhere in the body. Consideration of this rare entity is warranted in the workup of parapharyngeal masses.

Adult↗

PubMedDate not supplied

Papillary carcinoma of the thyroid occurring as multiple vascular tumors.

A case of advanced papillary carcinoma in a 16-year-old boy is presented. While this case is typical of the indolent and locally invasive character of papillary carcinoma, it is remarkable for the extent of tumor involvement appearing as reactive lymphadenopathy. The pronounced tumor vascularity and the similarity of the needle biopsy specimen to chemodectoma both conflicted with the initial diagnostic impression. The correct diagnosis was confirmed only with definitive surgical therapy.

Adolescent↗

PubMedDate not supplied

Ann Otol Rhinol Laryngol [Suppl].

Mandibular replacement subsequent to major extirpative head and neck surgery is predisposed to complications in the best of hands. The most suitable prosthesis appears to be the previously resected mandible, both from the standpoint of antigenicity and configuration. This study establishes that in the canine mandible a healthy, revitalized osseous network is reestablished subsequent to resection, freezing and replacement of the mandibular body when the graft is immobilized. The neoosteogenesis is borne out by in vivo (technetium 99, methylene diphosphonate scanning) and histopathological (tetracycline fluorescence and polarizing microscopy) studies. This early work in the canine suggests the potential for application in the human when the procedure is further refined and perfected.

Animals↗