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Biomedical subjects

C W Mende

Publications and source records attributed to C W Mende.

8 recordsLinked to original sources

Gallium-67 scintigraphy for the diagnosis and localization of perinephric abscesses.

Four patients with suspected perinephric abscess were evaluated by gallium-67 scintigraphy. Gallium-67 scintigraphs proved instrumental in correctly diagnosing and localizing 4 left perinephric abscesses. Roentgenographic examinations were negative in 2 cases. Gallium-67 scintigraphy can be a useful non-invasive technique to evaluate patients with suspected perinephric abscess.

Abscess

Gallium-67 scintigraphy and intraabdominal sepsis. Clinical experience in 140 patients with suspected intraabdominal abscess.

In 140 patients with suspected intraabdominal abscess, studies were made using gallium-67 citrate and technetium-99m labeled radiopharmaceuticals. Gallium-67 scintigrams correctly localized 52 of 56 intraabdominal abscesses confirmed at surgical operation or necropsy. In an additional 20 patients in whom findings on scintigrams were abnormal, there were clinically established infections. Sixty-one patients in whom findings on scintigrams were normal were conservatively managed and discharged from the hospital; none proved to have an abscess. Four false-negative and three false-positive studies were recorded. Gallium-67 scintigraphy is a useful noninvasive diagnostic adjunct that should be employed early in the evaluation of patients with suspected intraabdominal sepsis.

Abdomen

Resistance to acute renal failure afforded by prior renal failure: examination of the role of renal renin content.

In this study, rats recovering from glycerol-induced acute renal failure were found to be protected from mercury-induced nephropathy, and HgCl2 poisoning protected rats from developing myohemoglobinuric renal failure. In view of the widely disparate nature of the renal failure models used, refractoriness appears to relate to an altered sensitivity of the organism itself rather than reflecting resistance to a particular nephropathic challenge. Renal renin content of the rats at the time of rechallenge was normal or high, a finding which contrasts sharply with that of chronically saline-loaded animals which also are refractory to ARF but have a maximally suppressed renal renin content. Renal renin depletion is not essential to the prevention of acute renal failure in the rat.

Acute Kidney Injury

Gallium-67 and subpherenic abscesses--is delayed scintigraphy necessary?

Forty postoperative patients with clinical and roentgenographic findings suggestive of subphrenic abscess were evaluated by early and delayed 67Ga scintigraphy. Early 67Ga scintigraphs obtained 6 hr after injection correctly localized seven right and five left subphrenic abscesses. In no instance was an abscess present on delayed scintigraphs that was not evident on the 6-hr study. Two patients with left subphrenic abscess had false-negative results on both early and delayed scintigraphy. No false-positive studies were recorded. Early 67Ga scintigraphy can be a valuable noninvasive adjunct of the diagnosis of subphrenic abscess.

Adult

Gallium-67 for the diagnosis and localization of subphrenic abscesses.

Four septic patients with suspected subphrenic abscess were evaluated with gallium-67 citrate and technetium-99m labeled radiopharmaceuticals. Gallium-67 scintigraphs proved instrumental in correctly diagnosing and localizing one left and three right subphrenic abscesses. Gallium-67 scintigraphy can be a useful noninvasive technique for evaluating patients with suspected subphrenic abscess.

Adult

Early 67Ga scintigraphy for the localization of abnominal abscesses.

Sixty patients suspected of having abdominal abscesses were evaluated by early and delayed 67Ga scintigraphy. The 67Ga scintigraphs obtained 6 hr after injection correctly localized 18 of 20 abdominal or retroperitoneal abscesses. An additional 13 patients with abnormal scintigraphs had clinically established infections. In no instance was an abscess or inflammatory focus present on delayed scintigraphs that was no evident on the 6-hr study. Two false-positive and two false-negative studies were recorded. Early 67Ga scintigraphy is warranted in patients with suspected abdominal abscesses.

Abdomen