PubMed Health⌕ Search

Biomedical subjects

C Waymouth

Publications and source records attributed to C Waymouth.

12 recordsLinked to original sources
PubMed1976

Culture of cells in beem capsules: a new technique for electron microscopic study of monolayer cultures.

A method is described for the monolayer cultivation of primary cell suspensions and established cell lines directly in carbon-coated BEEM capsules, BEEM capsules are routinely employed by electron microscopists in tissue embedding procedures; growing monolayer cultures directly on the lids of inverted BEEM capsules presents the obvious advantage of maintaining cell to cell and cell to substratum conthaets with a minimum of stress and damage in the preparative steps for electron microscopy.

Cell Division↗
PubMed1976

Intradermal transplantation in mice of small numbers of sarcoma cells followed by tumor growth and regression.

Relatively small numbers of Sarcoma 1 cells were transplanted intradermally in A/WySn mice to study the course of growth when the size of the transplant is comparable to an early stage of spontaneous cancer. Transplants of 31 to 32,000 cells took one of three courses: no apparent growth; development of tumor followed by regression; or progressive growth. Transplants of 8,000 cells were the most evenly divided among these three courses and were selected for further study. Bilateral tumors took the same course to regression or to continued growth with significant frequency. There was complete correlation between regression of a tumor and immunity to a challenge made 1 to 5 weeks after the original transplant. Persistent tumors had a similar relationship, but the immunity was less complete. Limited, inapparent growth, followed by regression, was indicated in some mice, simulating immunological surveillance. Serum from such mice, when administered systemically in other mice, apparently induced enhancement of intradermal transplants.

Animals↗