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Biomedical subjects

C Wewetzer

Publications and source records attributed to C Wewetzer.

24 records · Page 2Linked to original sources

Follow-up investigation of family relations in patients with anorexia nervosa.

In a group of 22 formerly anorectic inpatients (follow-up 3.8 years after treatment) and in a control group of 24 paralleled young women, the subjective perception of the family structure was assessed using the "Subjective Family Image (SFI)", in order to investigate the question whether the family structure of former anorectics differs from the controls and whether individual development of the former inpatients is associated with the experienced family structure. Empirical results are in favor of the following two hypotheses: 1) Compared to the control group, formerly anorectic inpatients experience family relationships as more complicated and less satisfying. The quality of family relationships in the patient group is reduced, even at the time of follow-up. 2) Individual outcome (individual course of the illness) and quality of family relationships at time of follow-up are associated. Patients with a good outcome experience family relationships as more positive than patients with a poor outcome. The accordance of these findings to other empirical results and their implications for clinical practice are discussed.

Adult↗

The predictive value of depression in anorexia nervosa. Results of a seven-year follow-up study.

This study investigated the predictive value of depression in patients with adolescent anorexia nervosa. Thirty-four anorectic inpatients were assessed for DSM-III-R comorbid major depression at admission and at 3-year and 7-year follow-ups. Two standardized instruments, the Zung Self-rating Depression Scale and the Hamilton Depression Rating Scale, were applied to improve objective rating of depression. The findings suggest that severity of depressive symptoms at admission does not correlate with the severity of depression at follow-up, initial depressive psychopathology is not a valid prognostic indicator for the outcome of the eating disorder and at follow-up there is a highly significant relationship between depression and the outcome of anorexia nervosa. Patients with persisting eating disorder are also very likely to suffer from comorbid depression.

Adolescent↗

[Long term prognosis in anorexia nervosa].

Follow-up studies using the same prognostic criteria have shown that about 48% of the patients had recovered at follow-up, while 28% revealed further difficulties with eating, weight and figure, and 24% remained anorectic. Our own study on 103 patients who underwent inpatient treatment, revealed unexpectedly good results: according to the criteria of Morgan and Russell, 72% (n = 58) showed a good prognosis, 11% (n = 9) a fair, and 17% (n = 14) an unfavourable prognosis. 3 patients had died during the follow-up interval. It was possible to predict the long-term outcome from weight recovery during inpatient treatment, more successfully in patients with favourable than unfavourable outcome. The best predictors were: time until weight stabilization, the ratio ideal weight/stabilized weight, and age at onset of the eating disorder.

Adaptation, Psychological↗

Dermatologic findings in anorexia and bulimia nervosa of childhood and adolescence.

The cutaneous signs of anorexia nervosa (AN) and bulimia nervosa (BN) have been described previously in adult patients. For the first time, we present here dermatologic findings in children and adolescents suffering from eating disorders. Thirty consecutive young anorexic and bulimic inpatients (8 to 17 years of age, mean 15.1 years) underwent a standardized dermatologic examination. Patients were checked for abnormalities of the skin including atopic stigmata, dermographism, hair, nails, and oral cavity. Serum was obtained for hemoglobin, iron, zinc, GPT, thyroid, and sex-hormone levels. In 13 patients, the total serum IgE was determined, and a prick test was carried out with defined type I allergens. Findings in order of frequency included xerosis of the skin, white dermographism, diffuse hypertrichosis, acrocyanosis, scars, diffuse effluvium, artifacts, brittle nails, and onychophagia. Significant co-relations were found between the presence of hypertrichosis and the existence of amenorrhea or a body mass index of less than 16. In 22 patients a low T3 level was found. In summary, children and adolescents suffering from AN or BN show dermatologic features similar to those reported in older patients. Special findings in this age group are extensive lanugo hair and signs of autoaggressive behavior.

Adolescent↗