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Biomedical subjects

C Winckler

Publications and source records attributed to C Winckler.

14 recordsLinked to original sources

[Acute dyspnoea by acute thyroid abscess (author's transl)].

Infection is extremely rare in the pathology of the thyroid gland. One case is reported, and a review of the literature has helped to emphasize some specific points. Acute thyroiditis can be misdiagnosed in its initial phase because a fever by itself may not lead to a through examination of the neck, even if a goitre is present; the latter being the site of infection in the case reported. Dyspnoea of laryngeal origin proves to be a dangerous complication of thyroid abscesses. Treatment is always surgical, linked with appropriate antibiotic therapy. In the long run, thyroid function is unaffected.

Abscess

[Prevention of post-operative infection in heart surgery with extracorporeal circulation (apropos of 295 cases)].

From April 1977 to November 1978, 295 patients were operated on using artificial circulation. 31 p. 100 of these developed a post-operative infectious complication, 7.3 p. 100 being of a serious nature (3.3 p. 100 suffered from mediastinitis, and 4 p. 100 from septicaemia). The organisms responsible are, in the case of the mediastinal infections the staphylococcus Citreus, and Gram negative bacilli in the case of the septicaemias. A retrospective analysis shows that there are two successive periods and that in the course of the second there is a decrease in the occurence of all of the infections and particularly in the cases of mediastinitis. This improvment would seem on superficial analysis to correspond with a change in the preventive antibiotic treatment, the cephradine--gentamicin combination having replaced penicillin G. However, the statistical study shows that other factors were altered between the two periods (type of antiseptic, duration of treatments, time of postoperative intubation) and that these equally contributed to the fall in the incidence of infection. In the light of this study, it would seem that if prophylactic antibiotic treatment essentially directed against staphylococci has a place in cardiac surgery with artificial circulation, it can only be regarded as one of several preventive factors. The statistical data gathered so far is not sufficient to prove the efficacy of this treatment.

Adolescent

[Central vein catheters. Four unusual accidents (author's transl)].

Malpositioning of the tip of a central vein catheter is an accident whose frequency depends in part upon the puncture site. Certain dispositions are especially rare; the authors thus describe. Knotting in the left innominate vein after left internal jugular vein puncture. Catheterisation of the left internal mammary vein from the left subclavian vein. Intertion of a catheter in a pulmonary vein from the femoral route through a septal defect. And finally a thoracic aorta catheterisation by an unnoticed puncture of the left subclavian artery. The diagnostic steps and the conditions necessary to avoid the complications inherent to these malpositions are thereafter discussed.

Adolescent

[Rescue at sea].

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Disaster Planning

Lack of a significant protective effect of augmented circulating glucose on the ischemic myocardium.

This was a 60 year old woman, with a very large retro-pharyngeal tumour, mainly situated on the right, revealed by chronic decompensated respiratory failure. Admission to hospital was justified by deep coma with cyanosis of the face and extremities. She had taken 50 mg of Oxazepam the day before admission to hospital. This coma was due to chronic respiratory failure decompensated, as suggested by clinical and laboratory examination after elimination of any traumatic, neurological, endocrine or metabolic disorder. Intubation, rendered difficult by the retro-pharyngeal tumour and assisted ventilation permitted recovery of normal consciousness within 48 hours. This bi-lobed and encapsulated tumor was completely removed after full radiological assessment which showed the absence of any bony lesions. Histology suggested that this was a benign lipoma. The course was very rapidly favourable with a definite improvement in respiratory function one year after the surgical operation.

Animals