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Biomedical subjects

C Zetterberg

Publications and source records attributed to C Zetterberg.

At least 19 recordsLinked to original sources
PubMed2001

Improved recovery after music and therapeutic suggestions during general anaesthesia: a double-blind randomised controlled trial.

PURPOSE: This study was designed to determine whether music or music in combination with therapeutic suggestions in the intra-operative period under general anaesthesia could improve the recovery of hysterectomy patients. METHODS: In a double-blind randomised clinical investigation, 90 patients who underwent hysterectomy under general anaesthesia were intra-operatively exposed to music, music in combination with therapeutic suggestion or operation room sounds. The anaesthesia was standardised. Postoperative analgesia was provided by a patient-controlled analgesia (PCA). The pain scores were recorded by means of a visual analogue scale. Nausea, emesis, bowel function, fatigue, well-being and duration of hospital stay were studied as outcome variables. RESULTS: On the day of surgery, patients exposed to music in combination with therapeutic suggestions required less rescue analgesic compared with the controls. Patients in the music group experienced more effective analgesia the first day after surgery and could be mobilised earlier after the operation. At discharge from the hospital patients in the music and music combined with therapeutic suggestion group were less fatigued compared to the controls. No differences were noted in nausea, emesis, bowel function, well-being or length of hospital stay between the groups. CONCLUSION: This double-blind study has demonstrated that intra-operative music and music in combination with therapeutic suggestions may have some beneficial effects on postoperative recovery after hysterectomy. Further controlled studies are necessary to confirm our results.

Analgesics, Opioid↗
PubMed1999

Differences in risk factor patterns between cervical and trochanteric hip fractures. Swedish Hip Fracture Study Group.

The two types of hip fracture--cervical and trochanteric femoral fractures--are generally considered together in etiologic studies. However, women with a trochanteric fracture may be more osteoporotic than those with cervical hip fractures, and have higher post-fracture mortality. To explore differences in risk factor patterns between the two types of hip fracture we used data from a large population-based case-control study in Swedish women, 50-81 years of age. Data were collected by questionnaire, to which more than 80% of subjects responded. Of the cases included, 811 had had a cervical fracture and 483 a trochanteric fracture during the study period; these cases were compared with 3312 randomly selected controls. Height and hormonal factors appeared to affect the risk of the two types of hip fracture differently. For every 5 cm of current height, women with a cervical fracture had an adjusted odds ratio (OR) of 1.23 (95% CI 1.15-1.32) compared with an OR of 1.06 (95% CI 0.97-1.15) for women with trochanteric fractures. Later menopausal age was protective for trochanteric fractures (OR 0.95, 95% CI 0. 91-0.99 per 2 years) but no such association was found for cervical fractures. Compared with never smokers, current smokers had an OR of 1.48 (95% CI 1.12-1.95) for trochanteric fractures and 1.22 (95% CI 0.98-1.52) for cervical fractures. Current hormone replacement therapy was similarly protective for both fracture types, but former use substantially reduced risk only for trochanteric fractures: OR 0. 55 (95% CI 0.33-0.92) compared with 1.00 (95% CI 0.71-1.39) for cervical fractures. These risk factor patterns suggest etiologic differences between the fracture types which have to be considered when planning preventive interventions.

Age Factors↗
PubMed1998

Histology corresponding to mildly dyskaryotic smears--a study of 190 laser cone biopsied patients.

OBJECTIVES: The aim of the study was to evaluate the histological outcome of laser ring biopsies in patients with one or more smears showing cytological mild dyskaryosis where punch biopsies were not performed. The possibilities of predicting histological findings of CIN 2 and CIN 3 were analyzed. METHODS: The study comprised 190 laser ring biopsied patients with mildly dyskaryotic smears. Eighty-five patients were excluded from the initial 275 because of up- and downgrading of smears. Conization specimens and smears were reviewed by an experienced histopathologist and two experienced cytotechnicians. The histological findings were correlated to smear findings. RESULTS: Histologically, CIN 2 was found in 60 and CIN 3 in 45 patients (31 and 24%, respectively). The incidence of histological CIN 3 was higher in those with two or more mildly dyskaryotic smears and in those dyskaryotic smears lacking koilocytic change. Mildly dyskaryotic smears without endocervical cells indicated higher incidence of histological CIN 3. The fact that 36 of 96 CIN 2 and 3 lesions (38%) involved only 3 mm or less of the mucosa might be one important explanation for the absence of representative cells in the corresponding smears. CONCLUSIONS: Our study has shown that a mildly dyskaryotic smear is a strong indicator of CIN 2-3 histologically, especially in those cases without koilocytic cells and in those with repeatedly abnormal smears. The importance of inadequate sampling is indicated by higher incidence of histological CIN 3 in those with less than optimal smears. These findings are some of the factors to be taken into account when planning treatment strategies for this group of patients.

Adult↗
PubMed1997

Cervex-Brush vs. spatula and Cytobrush. A cytohistologic evaluation.

OBJECTIVE: To compare the efficacy of two cervical smear instruments, Cervex-Brush and spatula plus Cytobrush. STUDY DESIGN: Cervical smears were taken before laser ring biopsies in 213 women, who were randomized for the Cervex-Brush or spatula plus Cytobrush (S+C). The cytologic diagnosis was compared to the histologic diagnosis after laser ring biopsy. RESULTS: The correlation between cytology and histology showed comparable concordance (54% and 42%) for the two devices. In 130 (74 with Cervex-Brush and 56 S+C) patients, histology revealed moderate dysplasia or more advanced lesions. Those cases were further analyzed for smear failures. Negative smears were found in 13 cases (10 in the Cervex-Brush and 3 in the S+C group). This difference in favor of S+C was not, however, statistically significant. Significantly more false negative smears were found when endocervical cells were absent and in patients 30-39 years of age. CONCLUSION: Modern sampling devices, such as the Cervex-Brush and S+C, seem to be equally efficient in obtaining dysplastic squamous cells. Other factors of importance for nonrepresentative cervical smears should be studied in order to improve efficacy.

Adult↗
PubMed1995

Fixation of femoral neck fracture. A randomized 2-year follow-up study of hook pins and sliding screw plate in 222 patients.

We compared fixation with hook pins or sliding screw plate in a prospective randomized study of 222 patients with a cervical hip fracture. Radiographic evidence of early redisplacement, nonunion, or late segmental collapse was found in 43 of 122 patients operated on with two hook pins and in 40 of 100 patients operated on with the sliding screw plate. According to the actuarial method, the failure rate after 2 years was 38% with hook pins and 46% with screw plates, which not is a significant difference. Due to early redisplacement, reoperation with an endoprosthesis was performed within 0.5 (2) years in 11 (22) patients in the hook-pin group and in 4 (17) patients in the sliding-screw plate group.

Aged↗
PubMed1994

Bone mineral content and fixation strength of femoral neck fractures. A cadaver study.

We measured the bone mineral content (BMC) of 21 human femoral autopsy specimens using Radiographic Attenuation Technique (RAT). The specimens were then tested for stiffness in a material-testing machine. Osteosynthesis was performed after medial femoral neck osteotomy, using 1 of 3 different pinning methods: 2 hook pins (LIH), 2 cannulated screws (Uppsala), and 3 cannulated screws (CHP). The specimens were allocated to each method by grouping them in triplets with similar BMC. Cyclic loading at 500-1000 N and 1 Hz was performed during 50 minutes. The amount of axial compression during loading was measured. Finally, loading to failure was done and post-fixation stiffness and ultimate compression strength recorded. With one exception, all cases failed where the BMC was less than 0.4 g/cm2. No differences between the methods of osteosynthesis were found. The fixation strength was mostly dependent on the strength of the bone, i.e., the degree of osteoporosis.

Aged↗
PubMed1991

Workload and musculoskeletal problems: a comparison between welders and office clerks (with reference also to fishermen).

Previous studies have shown that subjective as well as clinical shoulder signs and symptoms are more common among welders than among office clerks. In the present study we wished to further evaluate the influence of different jobs on musculoskeletal problems, as well as the relationship between objective signs and subjective symptoms. This study confirmed that symptoms and signs from the shoulder were more common among the welders, who also had more subjective symptoms and clinical signs from other parts of the musculoskeletal system. Range of motion in different joint systems was, however, similar in the two groups except in external rotation of the shoulder, where welders had a more limited range. The degree of co-existence of subjective symptoms and clinical signs differed between different parts of the musculoskeletal system and was low particularly in the low back, hips, and ankles. This indicates low validity of many common clinical methods for determining musculoskeletal dysfunction. General health was good in both vocational groups and isometric strength for the welders was intermediate between that of office clerks (who had lower strength) and that of fishermen (who had higher strength, as disclosed in a previous investigation). To a similar degree welders and fishermen also had objective signs from most parts of the musculoskeletal system, whereas subjective symptoms from some parts of the body and medical consultations due to these problems were more common among welders. Atrophied shoulder muscles were more common among welders than among fishermen, whereas crepitations in the shoulder tended to be more common among the fishermen. This indicates that heavy dynamic work and prolonged static work may both induce shoulder injuries, but of different types.

Adult↗
PubMed1990

[The Svalebo program--successful rehabilitation of hip fracture patients].

The aim of the Svalebo programme is improved rehabilitation and increased home discharge of patients with hip fractures, and a better use of health care resources. The programme includes contact with the hip fracture patients at the orthopaedic clinic, a rehab programme on an outpatient basis 1-3 days a week. As a result of the programme, the role of the day hospital has become clearer and the flow of patients through the orthopaedic department has increased, the mean duration of hospitalisation having decreased by 30 per cent. In a one-year follow up of 42 patients, it was found that in many cases hip function was incompletely restored. In general, our view is that the Svalebo programme assures good care and rehabilitation of the hip fracture patient, and decreased consumption of institutional care facilities.

Activities of Daily Living↗
PubMed1990

[The standard hip--evaluation of physical function and health care utilization following hip fracture].

All 441 cases of hip fracture admitted to Sahlgrenska sjukhuset, Göteborg, during a one-year period were followed in accordance with a form developed by the Swedish Medical Research Council. Osteosynthesis was the method used in over 97 per cent of the cases. There were 336 women, mean age 80.0 (+/- 9.9) years, and 105 men, mean age 77.1 (+/- 11.8). A rehabilitation programme for non-institutionalised patients (68 per cent of the total of 441) reduced the length of stay at the orthopaedic department from 22 days to an average of 15 days in 1986, and the proportion of patients able to return home was increased from 81 per cent in 1982 to 90 per cent in 1987-88. Thus, the use of rehabilitation or nursing home facilities was reduced, and the length of stay there was reduced. The findings of the study also showed the rehabilitation to be time-consuming, and that few hip fracture patients ever regain complete pre-fracture function. Therefore it is suggested that the follow-up should be extended to cover a longer period than four months. Otherwise, the form is well designed, and its use improves the comparability of different studies.

Activities of Daily Living↗
PubMed1990

Musculo-skeletal symptoms and signs and isometric strength among fishermen.

Previous studies have shown that subjective symptoms from the musculo-skeletal system are common among fishermen. In the present study, physical signs of malfunction were also found to be common in this profession. The co-existence of physical signs and subjective symptoms differed greatly between different joint systems, and the correlation was in some locations very low. The prevalence of physical health problems other than orthopaedic problems was low. Isometric lifting strength was high compared to results reported on other vocational groups.

Adult↗
PubMed1990

Osteoporosis and back pain in the elderly. A controlled epidemiologic and radiographic study.

The incidence of back pain was investigated in hip fracture patients, 50-99 years of age, and in 70-, 75-, and 81-year-old controls from the same population. The prevalence of vertebral fractures were evaluated from spinal radiographs. Eighty hip fracture patients and 103 controls, all between 70 and 75 years of age, were included in the radiographic study. The incidence of back pain of the controls was twice that of the hip fracture patients, 45-48% compared with 23-20%, respectively, for both female and male subjects. Conversely, vertebral fractures were radiographically shown in 43% of the hip fracture patients and in 22% of the controls. Thus, the major explanation for longstanding back pain in the elderly does not appear to be related to spinal osteoporosis.

Aged↗