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C Zippin

Publications and source records attributed to C Zippin.

At least 19 recordsLinked to original sources
PubMed1995

Completeness of hospital cancer case reporting from the SEER Program of the National Cancer Institute.

BACKGROUND: To ascertain the quality of data entering a population-based reporting system, an essential requirement is to study levels of completeness of case-ascertainment and reporting. This study represents an effort to quantify completeness of case reporting in the SEER (Surveillance, Epidemiology, and End Results) Program of the National Cancer Institute. METHODS: Hospitals in each of the participating SEER areas were stratified according to their annual hospital cancer caseload for the year 1987. Within each caseload stratum, a random sample of hospitals was selected for inclusion in this study. Files in the medical record, pathology, and radiation oncology departments in each hospital were reviewed for SEER reportable cases. These cases were then matched against SEER case listings to identify unreported cases. RESULTS: The crude estimated completeness of reporting for 1987 in the six participating SEER areas was 97.7% and the registry-caseload standardized rate was 96.8%. Variation was noted by SEER registry, hospital cancer caseload, and casefinding source (hospital department). Three-quarters of unreported cases were of invasive disease and one-fourth were in situ, primarily of the cervix uteri. CONCLUSIONS: There is variation in completeness of casefinding among SEER registries, hospital size, and hospital department source. Additional factors that appear to be related to case ascertainment are cancer site or type and who performs the casefinding function (hospital registry or central registry staff).

Female↗
PubMed1993

Characteristics of cancer patients under the age of 20 at medical centers in Israel and the West Bank: a preliminary study.

This paper describes the demographic experience on 373 young cancer patients (less than 20 years of age) at two oncology centers initiated in Israel by one medical team in 1975-1977. These units are the Assaf Harofeh Medical Center (AHMC), which predominantly serves a Jewish population (103 cases); and the West Bank Cancer Unit (WBCU), which provides similar care services to the Arab population of the West Bank (270 cases). The two centers have the unique feature of serving two populations residing in close relationship but still differing in many cultural and socioeconomic characteristics. The Arab patients at WBCU tended to be younger than the Jewish children at AHMC. The five most common diagnostic sites for both AHMC and WBCU included hematopoietic system, bones and joints, soft tissue, urinary tract, and brain and nervous system, although not in the same order of occurrence. These tumor sites accounted for approximately 80% of the cases at each center. The experience with WBCU patients was also compared with data for all Jews in Israel. This comparison identified for both sexes combined statistically significant differences in relative frequency of tumors of soft tissue, eye and orbit, brain and nervous system, and thyroid gland. If confirmed by additional data, reasons for the suggested excess risks should be pursued through more definitive epidemiological studies.

Adolescent↗
PubMed1993

Study of completeness of the surveillance, epidemiology and end results (SEER) program case ascertainment by hospital size and casefinding source.

Factors that may enter into the completeness/incompleteness of reporting include: 1. The competence and diligence of staff. 2. Familiarity with the record systems used within each hospital department. This limited review suggested that hospitals employing their own staff for case ascertainment achieved somewhat higher completeness of reporting rates compared with institutions that relied on central registry circuit riders to pick up cases. 3. Where cases are identified through computer listings by diagnosis, errors in the coding of some cases may result in the exclusion of these cases. 4. The use of ambiguous diagnostic terms may contribute to missing cases.

Female↗
PubMed1991

Cancer patterns at medical centers in Israel and the West Bank.

This paper describes the oncological experience on 7,216 patients at two cancer units initiated by one medical team in 1975-1977 at Assaf Harofeh Medical Center in Israel (predominantly serving a Jewish population, 4,671 cases) and at the West Bank Cancer Unit (WBCU), which serves an Arab population (2,545 cases). The two centers have the unique feature of serving two populations residing in close geographic proximity but differing in many cultural and socioeconomic characteristics. Data from the ongoing cancer registries in these two centers are summarized and compare the demographic characteristics of the two study groups, anatomic sites of cancer, methods of diagnosis and extent of disease. The findings at the two centers suggest the presence of different risk factors influencing the site distributions of cancers seen in the two populations served. Among the findings, significantly higher (p less than 0.05) estimated relative risks for cancers of the digestive and urinary-genital systems are observed in each sex group at AHMC than at WBCU. Alternatively, the estimated risk of head and neck cancers was significantly higher among both males and females at WBCU compared with their counterparts at AHMC. Differences in risk were also noted for a number of specific anatomic sites of cancer.

Age Factors↗
PubMed1988

Breast cancer at medical centers in Israel, the West Bank, and the United States.

A comparison is made of the characteristics of female breast cancer patients, their diseases, and treatment practices in medical centers in Israel and the West Bank of the Jordan River. This experience is further compared with tumor registry data from a major medical center in the United States. Differences are found in the age distributions of patients, marital status, parity, stage of disease at diagnosis, delay between onset of symptoms and diagnosis as well as between diagnosis and treatment. Some of these observations reflect differences in population characteristics, sociocultural practices and local attitudes toward disease, its diagnosis and management.

Adult↗
PubMed1985

Cancer data systems.

Explore the source record for details and available documents.

Abstracting and Indexing↗
PubMed1981

Late effects of radiation therapy for cancer of the uterine cervix.

This report presents follow-up information on 497 women diagnosed with cancer of the uterine cervix in Connecticut and California between 1932 and 1951 who received only radiation as their initial course of therapy. Patients entered into the study were all treated before age 55 and all were five-year-survivors following treatment in order to eliminate early deaths due to the cervical cancer. Three radiologic dosage groups (high, medium, and low) were formed with 93, 244, and 160 patients, respectively. For all dosage groups combined 108 subsequent cancers were observed more than 5 yr after cancer treatment compared with 64 expected (P less than 0.01). Sites for which subsequent cancers were significantly (P less than 0.05) in excess of expectation were rectum, ovary, lung, vulva and vagina, small intestine, oropharynx, and central nervous system excluding brain. The ratio of observed to expected cases of subsequent cancers rose only slightly with increasing radiologic dose. No significant differences in overall survival patterns for the three dosage groups were found. For all dosage groups survival was poorer than in the corresponding segment of the general population.

Adult↗
PubMed1979

Staging of cancer of the colon and cancer of the rectum.

A retrospective analysis of 1,826 cases (924 colon, 902 rectal) from ten institutions provided the basis of this study on the staging of cancer of the colon and rectum. The general rules of the American Joint Committee on the relationship between times and the staging of cancer have been followed. These represent modifications of the originally formulated TNM system of the Union Internationale Contre Le Cancer (UICC) which has been designed as a clinical-diagnostic classification, not applicable to cancer of inaccessible sites or structures requiring postsurgical treatment pathologic assessment of therapeutically removed specimens. Inadequacies of the clinical data requested for our study required adoption of the pTNM evaluation method of classification. Multiple regression analysis of the data demonstrated a relationship between survival and the following: depth of penetration (T), status of regional lymph nodes (N), and presence or absence of distant metastasis (M). This was similar for both sites. Basically, for the rectum it was in consonance with the original Dukes' classification (A, B, and C), and was remarkably applicable to the colon. The survival data for the two sites were so similar as to suggest the use of one set of pTNM categories not only for the postsurgical-treatment pathologic evaluation, but also for the stage grouping definitions. Strongly recommended for cancer of all sites is the development of General Oncology Data Forms to be included in the clinical charts and records of all patients with cancer.

Adult↗
PubMed1979

Marital and reproductive histories of women with cancer of the breast and their sisters.

In a study of 45 pairs of sisters-each pair including one sister with cancer of the breast and one without the disease-differences in marital and reproductive histories were observed. These differences included less frequent marriage, later marriage, fewer children, and a longer delay between date of marriage and the first pregnancy in the sisters with the disease. These findings appear to confirm presently known reproductive risk factors for cancer of the breast, but they also raise the possibility that unknown behavioral factors influencing the endocrine system may be delaying marriage and pregnancy.

Adult↗
PubMed1975

Time trends in survival in acute lymphocytic leukemia.

Comparison of patients under 20 years of age with acute lymphocytic leukemia diagnosed in 1955-64 with those whose disease was diagnosed in 1965-69 revealed a marked improvement in median survival time, from 9.5 to 16.8 months. This improvement occurred among patients with less favorable hematologic and symptomatic characteristics as well as among patients with more favorable ones. However, a shift in patient characteristics was consistent with the concept of diagnosis earlier in the natural history of the disease. In the more recent period, fewer patients were classified as severely disabled, and a somewhat higher proportion were in more favorable categories with respect to platelet count, percent of polymorphonuclear leukocytes, organomegaly, and bleeding or infection. Initial treatment was markedly different during the two time periods; this reflected a shift toward the use of combinations of chemotherapeutic agents and steroids.

Adolescent↗