PubMed Health⌕ Search

Biomedical subjects

C Zugerman

Publications and source records attributed to C Zugerman.

9 recordsLinked to original sources
PubMed1990

Chloracne. Clinical manifestations and etiology.

Chloracne is a rare but important acneiform eruption often associated with the ingestion of chlorinated phenolic agents such as dioxins with subsequent toxicity from these chemicals. Clinically, chloracne can be distinguished from acne vulgaris by the distribution and appearance of the lesions and by taking a detailed history. In some instances, it may be associated with particularly xerotic skin, pigmentation, follicular hyperkeratosis, conjunctivitis, and actinic elastosis. Histologically, the primary lesion is a follicular plug containing keratinous material. Chloracne is difficult if not impossible to treat adequately and once present, may persist for years. Consequently, good hygiene, safe manufacturing processes so that no inhalation or skin contact is possible, and the elimination of atmospheric contamination are all necessary in the prevention of this potentially debilitating disease.

Age Factors↗
PubMed1986

Histiocytosis X. Flow cytometric DNA-content and immunohistochemical and ultrastructural analysis.

A 76-year-old man developed a generalized orange-red nodular eruption associated with constitutional symptoms. A biopsy specimen of a nodule revealed an extensive infiltration of histiocytes with relatively abundant cytoplasm and folded nuclei. Electron microscopy showed Langerhans' cell granules, which confirmed the diagnosis of histiocytosis X. Results of immunohistochemical studies revealed a pattern of antigen expression usually found in histiocytosis X, including Ia, T6, and S100. Analysis of the DNA content of the cells with flow cytometry revealed an aneuploid peak. The patient responded partially to topical mechlorethamine hydrochloride therapy.

Adult↗
PubMed1986

The lips: anatomy and differential diagnosis.

The lips are composed of striated muscle and connective tissue and are anatomically positioned to be maximally exposed to sunlight, environment, food, and tobacco. A number of topics relevant to the lips are presented, including contact dermatitis, contact urticaria, benign and malignant systemic processes, and the effect of systemically administered pharmacologic agents on the lips.

Cheilitis↗
PubMed1985

Contact dermatitis to yellow iron oxide.

After epicutaneous patch testing, a 43-year-old non-atopic white female with eyelid dermatitis was found to be allergic to yellow iron oxide used as a dye in her mascara. Yellow iron oxide, also known as limonite or yellow ochre, is a common cosmetic dye which has not previously been described as a source of contact dermatitis. Formulation of mascara as well as classification of naturally occurring iron oxides are discussed.

Adult↗
PubMedDate not supplied

Cutting fluids. Their use and effects on the skin.

Metalworking fluids are liquids that flow or are sprayed over metal that is being altered mechanically or physically. Cutting fluids tend to be alkaline and are often soap-like. As such they denature keratin, defat the skin, and remove water from it, causing dryness, fissures, and frank eczematization. Cutting oil dermatitis is a difficult problem for the involved worker who must continue to support his family despite the presence of this progressive, pruritic, and painful eruption.

Dermatitis, Contact↗