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Biomedical subjects

C de Carlini

Publications and source records attributed to C de Carlini.

5 recordsLinked to original sources
PubMed1977

Enflurane metabolism and postoperative renal function.

Inorganic fluoride concentrations in blood and urine were measured in 22 gynaecological patients during and after anaesthesia with enflurane and post-operative renal function was investigated. Ten patients (group I) were given 0.6 vol.% enflurane, and 12 patients (group II) a mixture of 0.6 and 0.8 vol.% enflurane. The serum fluoride concentration of arterial blood reached, in group I, after 120 min 18,99 micronmol/1 whereas in group II the concentration was 21 micronmol/1. One hour after the end of anaesthesia the fluoride concentration in venous blood were nearly identical in both groups and decreased in the following 12 h evenly. In all patients relatively high postoperative fluoride concentrations were observed in the urines. No evidence of renal dysfunction was found after anaesthesia.

Adult↗
PubMed1977

[Enflurane and fluorconcentrations in maternal and fetal blood during anaesthesia for for caesarean Section (authors transl)].

During anaesthesia for caesarean sections, the placental transfer and metabolism of Enflurane were investigated in 14 cases. In 3 cases, the administered concentration of 0.4 vol.% Enflurane showed too slight anaesthesia. In 11 cases, 0.6 vol.% Enflurane were delivered to the maternal respiratory mixture. A gaschromatographic method was used to measure the maternal and fetal blood concentrations of Enflurane. The calculated maternal mean value of Enflurane showed a concentration of 330 mumol/l which corresponds to 6.07 mg/100ml; the fetal mean value was 148 mumol/l or 2.72 mg/100 ml. This means that during operating time about 44.8% from the maternal Enflurane concentration has crossed to the fetus. The metabolic break down of Enflurane could be demonstrated by the measurement of inorganic fluorides in the maternal and fetal blood. The fluor concentration in the maternal blood increased during the operation and reached a mean value of 15.5 mumol/l at the time of birth; the mean value in the cord vein was at the same time 9.28 mumol/l which corresponds to 61% of the maternal concentration.

Anesthesia, Obstetrical↗