Biomedical subjects
Publications and source records attributed to CC Lin.
We describe new techniques involving trapped atoms as targets for measurements of electron-impact ionization cross sections out of an excited level. By directly detecting the ions formed by electron collisions, we have obtained the first experimental ionization cross sections out of the 5(2)P excited level in rubidium at energies from 40 to 300 eV.
In therapeutic areas aimed at developing an orally administered drug, the pharmacokinetic profile of a drug candidate after oral administration in vivo is pivotal in evaluating its success. This can be done by monitoring the plasma concentration versus time after dosing and calculating the area under the curve (AUC). The authors describe a novel screening protocol in which an estimated AUC can be determined, allowing the rapid evaluation of large numbers of compounds and providing a rank order of estimated AUC values to prioritize compounds for further investigation.
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