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Biomedical subjects

Cağri Yazgan

Publications and source records attributed to Cağri Yazgan.

2 recordsLinked to original sources

[Social phobia in essential tremor].

OBJECTIVES: This study is aimed to determine the frequency of social phobia among a group of subjects with essential tremor, to compare subject groups with and without social phobia with regard to the level of social phobia and disability, and to study the effect of the severity of social phobia on disability in essential tremor. METHOD: 45 subjects, diagnosed with essential tremor were included in the study, and their severity of tremor and essential tremor-related functional impairment were determined. Subjects were evaluated in 2 groups; those with a social phobia diagnosis and those without, as determined with the SCID-I interview. Additionally, the Liebowitz Social Anxiety Scale (LSAS) and the Sheehan Disability Scale (SDS) were administered to both groups and the findings were statistically compared. RESULTS: Social phobia was observed in 19 subjects (42.2%) with essential tremor. While no difference was found between the groups in terms of tremor severity scores, the mean score of tremor-related functional disability in the social phobia group was found to be higher. Among subjects with social phobia, the mean fear and avoidance scores on LSAS were higher, whereas social lives and leisure activities of the same group were observed to have been affected more, according to SDS scores. Social avoidance and tremor severity were predictive for the difference on SDS. A significant and positive correlation between fear and avoidance, and disability in the group with social phobia was established. CONCLUSION: It was concluded that essential tremor patients diagnosed with social phobia demonstrated higher social anxiety and disability compared to those without social phobia, and that social avoidance contributed to disability. Identifying social phobia in essential tremor patients and diagnosing these patients with social phobia, contrary to DSM's restrictive approach, would be appropriate and beneficial in terms of providing sufficient treatment.

Adult↗

[Mild cognitive impairment].

It is essential to determine whether memory impairment is accompanied by impairment in other cognitive areas in patients presenting with the complaint of forgetfulness. Furthermore, it should be established whether this impairment is associated with normal aging or dementia. Several terms have been suggested to identify cognitive disorders without dementia. Benign senescent forgetfulness, age-associated memory impairment and aging-associated cognitive decline are considered to fall within the limits of normal aging. A recently proposed term, mild cognitive impairment, as opposed to the terms mentioned above, identifies a transitional state between normal aging and dementia. With the use of criteria proposed for mild cognitive impairment, this disorder converts to Alzheimer's disease at a rate of 10-15 % yearly. However, in longitudinal studies different neuropsychological tests and assessment scales were used for the diagnosis of mild cognitive impairment, resulting in different conversion rates to Alzheimer's disease. Recently, it has been proposed to classify mild cognitive impairment according to memory and non-memory involvement as amnestic, multiple domain and non-memory single domain clinical subtypes. Furthermore, vascular, metabolic, traumatic and various etiologies other than degenerative etiology are mentioned. Besides the medications known to be effective for cognitive dysfunctions, memory enhancement training is suggested for treatment. A consensus on the diagnostic criteria for mild cognitive impairment, determining the subgroups and further studies on treatment are necessary.

Cognition Disorders↗