Biomedical subjects

Capri-Mara Fillmore

Publications and source records attributed to Capri-Mara Fillmore.

3 recordsLinked to original sources

PubMed2004

Insulin-like growth factors, insulin-like growth factor-binding proteins, and endometrial cancer in postmenopausal women: results from a U.S. case-control study.

OBJECTIVE: To assess whether circulating insulin-like growth factor-1 (IGF-1), IGF-2, insulin-like growth factor-binding protein-1 (IGFBP-1), or IGFBP-3 were associated with endometrial cancer in postmenopausal women. STUDY DESIGN: Between 1987 and 1990, we conducted a case-control study of 405 women with endometrial cancer and 297 matched population-based controls. This analysis included 174 postmenopausal cases and 136 controls. RESULTS: In logistic regression models adjusted for potential confounders, higher IGF-1 levels were not positively associated with endometrial cancer: odds ratio (OR) for the highest tertile versus the lowest tertile = 0.63, 95% confidence interval (CI) = 0.30-1.32. Endometrial cancer was inversely associated with IGF-2 (OR for the highest tertile = 0.35, 95% CI = 0.18-0.69) and IGFBP-3 (OR for the highest tertile = 0.40, 95% CI = 0.21-0.77), and not associated with IGFBP-1. CONCLUSION: Serum IGF-1, IGF-2, and IGFBP-3, but not IGFBP-1, were inversely associated with endometrial cancer in postmenopausal women. These associations and the potential role of the IGF system in endometrial proliferation and carcinogenesis warrant further research.

Adult↗

PubMed2004

Postpartum depression: identification, screening, and treatment.

Depression during the postpartum period is a significant public health concern, affecting 8%-15% of women and resulting in considerable morbidity for women, and their infants and families. Risk, prevalence, and distinguishing features of postpartum mood disorders are provided. Anxiety and depression frequently co-occur, suggesting symptoms of anxiety should also be attended to when screening for postpartum depression. Recommendations include the use of a brief, valid screening instrument as a routine clinical practice and the unique role of the obstetrician/gynecologist, pediatrician, and family practice physician in identification and referral. A summary of evidence-based treatment options for postpartum depression, along with current information about psychotropic medication, is provided to assist in risk-benefit analyses and decision making with patients.

Antidepressive Agents↗

PubMed2003

Follow-up of abnormal results in an urban community-based breast cancer screening program.

OBJECTIVE: Determine the rates of follow-up for abnormal mammograms and see how they compare with rates of similar programs elsewhere. DATA: Records from 1990-2000 of the Breast Cancer Awareness Program were analyzed and reviewed to determine follow-up rates. RESULTS: The follow-up rate for all 11 years was 85%; during the last 7 years the rate has been 90%. CONCLUSION: Follow-up rates were as good and generally better than those reported in the literature for similar programs. The rates, though good to begin with, improved with the more rigorous training and requirements of the Wisconsin Well Women's Program.

Adult↗