Carl-Gustaf Laurell | PubMed Health

PubMed2004

Posterior capsule opacification after phacoemulsification in patients with postoperative steroidal and nonsteroidal treatment.

PURPOSE: To evaluate the effect of dexamethasone, diclofenac, and a placebo given for 3 weeks after phacoemulsification and intraocular lens (IOL) implantation on the formation of posterior capsule opacification (PCO). SETTING: St. Erik's Eye Hospital, Stockholm, Sweden. METHODS: In a 2-year prospective randomized double-blind study, a laser flare meter was used to measure aqueous flare intensity preoperatively and 3 days, 2 weeks, and 2 years after phacoemulsification and IOL implantation. Posterior capsule opacification was evaluated 2 years postoperatively using retroillumination images taken with a Scheimpflug camera. The Evaluation of Posterior Capsule Opacification system was used to score the areas of PCO density. RESULTS: The median rate of PCO 2 years after phacoemulsification was 0.72 (range 0.32 to 1.57) in the dexamethasone group, 0.78 (range 0.19 to 2.14) in the diclofenac group, and 0.70 (range 0.35 to 1.70) in the placebo group. The differences were not statistically significant (P>.05; Kruskal-Wallis analysis of variance, multiple comparisons). The rate of neodymium:YAG laser posterior capsulotomy during the 2 years after surgery was not statistically different between groups (P>.05, chi-square test). There was no correlation (Spearman rank coefficient) between laser flare measurements and PCO formation in any group during the study (P>.05). CONCLUSION: Topical instillation of diclofenac, dexamethasone, or a placebo in the immediate period after phacoemulsification and IOL implantation did not seem to influence the formation of PCO 2 years after cataract surgery.

Administration, Topical↗

PubMed2004

Computer-simulated phacoemulsification.

OBJECTIVE: To develop a simulator for training in phacoemulsification to be used as a learning device for both beginners and experienced surgeons to shorten the learning curve. DESIGN: Experimental study. METHODS: The system consists of a personal computer, a 3-dimensional visual interface, a phacoemulsification handpiece, and a nucleus manipulator and foot pedals for control of the phacoemulsification procedure and microscope adjustments. The simulation is based on generalized simulation software that can be also used for the development of other medical simulations. MAIN OUTCOME MEASURES: Qualitative statements given in a questionnaire. Medical students and ophthalmic surgeons with varying experience of phacoemulsification were tested. RESULTS: A simulator for training in phacoemulsification has been developed. The surgical procedures can be practiced any number of times, and there is no risk to patients. The efforts of the surgeon can be evaluated objectively. CONCLUSIONS: Studies have shown that the number of complications for an ophthalmic surgeon learning phacoemulsification decreases exponentially, reaching close to the asymptote only after several hundred procedures. Simulator training might shorten the learning period, reduce expensive supervision by an experienced surgeon, and maintain and improve the skills of experienced surgeons.

Computer Simulation↗