Biomedical subjects

Carmen Manciuc

Publications and source records attributed to Carmen Manciuc.

4 recordsLinked to original sources

PubMedDate not supplied

[Acute viral encephalitis. Experience of the Iaşi Infectious Disease Clinic between January 2000 and March 2003].

We analyzed the patients files suffered from acute viral encephalitis in 39 months period: January 2000-march 2003. According to our data there was a total of 33 patients; one of them died. The most involved patients were male and of the 8-14 year group of age; for the first three month in 2003 were admitted 11 patients. Coma and seizures were the most frequent clinical signs. LCR had the usual abnormalities for the above mentioned disease; the treatment was mainly performed with corticosteroids; 28 cases were admitted more than 8 days period. The evolution of the clinical status was satisfactory for all 32 patients.

Acute Disease↗

PubMedDate not supplied

[Lamivudine and alpha-IFN treatment of a severe case of acute hepatitis B].

In order to enhance the viral clearance we used a combined antiviral therapy in an 18 year old patient, hospitalized in the Infectious Diseases Hospital-Iaşi, in June 2002. The evolution under standard therapy was unsatisfactory, with the aggravation of the icteric syndrome and a constant cytolytic syndrome. At this point we used the combination of Lamivudine (Zeffix) 100 mg/24 h + alpha-IFN 3 milUI x 3/week for the duration of 8 weeks. The improvement in both clinical and biochemical condition of the patient was obvious. At the end of the treatment (8 weeks) none of the signs or symptoms were present, the patient became AgHBs negative, AgHBe negative and anti-HBe positive. The combined antiviral therapy was useful (with the clearance of the HBs antigen) in a severe case of acute hepatitis B.

Adolescent↗

PubMedDate not supplied

[Tetanus in childhood--experience at the Infectious Disease Hospital Iaşi, January 1980-October 2003].

The aim of our study is to present the tetanus pediatric cases for almost 24 year period. We analyzed epidemiologically, clinico-biologically and the treatment from the patients' files. In above mentioned period were admitted 8 children with tetanus, 4 cases in 1980-1990; 5 patients were female, mainly came from suburban area; 12-15 year old group of age was mainly involved-3 cases. A point of entry was certified in 7 cases, the mean incubation period was 9.2 days, all the cases had a typical form of the disease. The complications were: bronchopneumonia, ileus (1 case). The performed treatment--antitetanic serum, antibiotics, sedatives, curare for 3 patients; no patient died. A rare disease for the pediatric age, tetanus could be a severe disease, with severe complications.

Adolescent↗

PubMedDate not supplied

[Necrotizing fasciitis].

The management of a right foot necrotizing fasciitis and severe sepsis in an old diabetic patient is presented. The early and aggressive surgery, adequate antibiotherapy and correction of organic disfunction (cardio-circulatory, renal, respiratory) eliminated the vital risk and resulted in a satisfactory morpho-functional recovery of the foot.

Aged↗