Biomedical subjects

Carol J Mottram

Publications and source records attributed to Carol J Mottram.

4 recordsLinked to original sources

PubMed2006

Time to task failure varies with the gain of the feedback signal for women, but not for men.

Varying the gain of the feedback signal during a target-matching task alters the synaptic input onto the motor neuron pool. The purpose was to determine the influence of the gain of the feedback signal on the time to failure for men and women when maintaining arm position while supporting a submaximal inertial load with the elbow flexor muscles. While seated with the upper arm vertical, 15 women and 14 men maintained a constant elbow angle (1.57 rad) and supported a load equal to 15% of maximal voluntary contraction (MVC) force until failure. The task was performed on separate days with either a low gain or a high gain for the joint-angle signal. The percent decline in MVC force after the fatiguing contraction was similar for the low- and high-gain conditions (P = 0.24), and did not differ for men and women (P = 0.11). The discharge of motor units in biceps brachii declined at a greater rate during the high-gain condition for men and women, but only the women experienced a briefer time to failure for the high-gain session (8.7 +/- 2.3 min) compared with the low-gain session (11.9 +/- 4.8; P = 0.003). The men had similar times to failure for the low- (6.0 +/- 2.2 min) and high-gain conditions (5.9 +/- 2.1 min; P = 0.35). Linear and stepwise, multiple-regression analyses revealed that the time to failure for the men was associated with the absolute target force, the standard deviation (SD) for the resultant wrist acceleration, and the brachialis aEMG (P <or= 0.02), whereas the time to failure for the women was associated with the rate of decline in motor unit discharge, the SD for the resultant wrist acceleration, and the changes in mean arterial pressure and heart rate (P <or= 0.001). Despite each subject exerting the same net muscle torque during the two gain conditions and a similar effect of feedback gain on the discharge rate of motor units for all subjects, the time to failure for the fatiguing contractions was limited by different mechanisms for the men and women.

Adolescent↗

PubMed2005

Prolonged vibration of the biceps brachii tendon reduces time to failure when maintaining arm position with a submaximal load.

Vibration reduces the amplitudes of the tendon jerk response and the Hoffmann and stretch reflexes in the muscle exposed to the vibration, yet does not alter the time to task failure when the task involves exerting a submaximal force against a rigid restraint. Because the amplitude of the stretch reflex is greater when a limb acts against a compliant load than a rigid restraint, the purpose was to determine the influence of prolonged tendon vibration on the time to failure when maintaining limb position with the elbow flexor muscles. Twenty-five healthy men performed the fatiguing contraction by maintaining elbow angle at 1.57 rad until failure while supporting a load equal to 20% of maximal voluntary contraction (MVC) force. The fatiguing contraction was performed on 3 separate days with different levels of vibration applied to the biceps brachii tendon: no vibration, subthreshold for a tonic vibration reflex (TVR), and suprathreshold for a TVR. MVC force before the fatiguing contraction was similar across the three sessions (mean of 3 sessions: 313 +/- 54 N, P = 0.83). Despite a similar decline in MVC force after the fatiguing contraction across conditions (-18.0 +/- 8.0%, P > 0.05), the time to task failure was 3.7 +/- 1.4 min for the suprathreshold TVR condition, 4.3 +/- 2.1 min for the subthreshold TVR condition, and 5.0 +/- 2.2 min for the no-vibration condition (P < 0 0.001). The average EMG of the elbow flexor muscles was similar (P = 0.22) during the fatiguing contractions. However, the fluctuations in limb acceleration at task onset were greater for the suprathreshold TVR condition (P < 0.01), but were not different between the subthreshold TVR and no-vibration conditions (P > or = 0.22). Furthermore, the difference in the SD of limb acceleration between the no-vibration and vibration conditions was correlated with the difference in time to failure for the no-vibration and subthreshold TVR conditions (P = 0.03; r2 = 0.22), but not for the no-vibration and suprathreshold TVR conditions (P = 0.90; r2 = 0.001). These findings indicate that prolonged vibration reduced the time to failure of a sustained contraction when subjects maintained limb position, suggesting that peripheral inputs to the motor neuron pool play a significant role in sustaining a contraction during tasks that require active control of limb position.

Adaptation, Physiological↗

PubMed2005

Frequency modulation of motor unit discharge has task-dependent effects on fluctuations in motor output.

The rate of change in the fluctuations in motor output differs during the performance of fatiguing contractions that involve different types of loads. The purpose of this study was to examine the contribution of frequency modulation of motor unit discharge to the fluctuations in the motor output during sustained contractions with the force and position tasks. In separate tests with the upper arm vertical and the elbow flexed to 1.57 rad, the seated subjects maintained either a constant upward force at the wrist (force task) or a constant elbow angle (position task). The force and position tasks were performed in random order at a target force equal to 3.6 +/- 2.1% (mean +/- SD) of the maximal voluntary contraction (MVC) force above the recruitment threshold of an isolated motor unit from the biceps brachii. Each subject maintained the two tasks for an identical duration (161 +/-93 s) at a mean target force of 22.4 +/-13.6% MVC. As expected, the rate of increase in the fluctuations in motor output (force task: SD for detrended force; position task: SD for vertical acceleration) was greater for the position task than the force task (P < 0.001). The amplitude of the coefficient of variation (CV) and the power spectra for motor unit discharge were similar between tasks (P > 0.1) and did not change with time (P > 0.1), and could not explain the different rates of increase in motor output fluctuations for the two tasks. Nonetheless, frequency modulation of motor unit discharge differed during the two tasks and predicted (P < 0.001) both the CV for discharge rate (force task: 1-3, 12-13, and 14-15 Hz; position task: 0-1, and 1-2 Hz) and the fluctuations in motor output (force task: 5-6, 9-10, 12-13, and 14-15 Hz; position task: 6-7, 14-15, 17-19, 20-21, and 23-24 Hz). Frequency modulation of motor unit discharge rate differed for the force and position tasks and influenced the ability to sustain steady contractions.

Acceleration↗

PubMed2004

Motor-unit activity differs with load type during a fatiguing contraction.

Despite a similar rate of change in average electromyographic (EMG) activity, previous studies have observed different rates of change in mean arterial pressure, heart rate, perceived exertion, and fluctuations in motor output during the performance of fatiguing contractions that involved different types of loads. To obtain a more direct measure of the motor output from the spinal cord, the purpose of this study was to compare the discharge characteristics of the same motor unit in biceps brachii during the performance of two types of fatiguing contractions. In separate tests with the upper arm vertical and the elbow flexed to 1.57 rad, the seated subjects maintained either a constant upward force at the wrist (force task) or a constant elbow angle (position task) for a prescribed duration. The force and position tasks were performed in random order at a target force equal to 3.5 +/- 2.1% (mean +/- SD) of the maximal voluntary contraction (MVC) force above the recruitment threshold of the isolated motor unit. Each subject maintained the two tasks for an identical duration (161 +/- 96 s) at a mean target force of 22.2 +/- 13.4% MVC (range: 3-49% MVC). The dependent variables included the discharge characteristics of the same motor unit in biceps brachii, fluctuations in motor output (force or acceleration), mean arterial pressure, heart rate, and rating of perceived exertion. Despite similar increases in the amplitude of the averaged EMG (% MVC) for the elbow flexor muscles during both tasks (P = 0.60), the rates of increase in mean arterial pressure (P < 0.001), rating of perceived exertion (P = 0.023), and fluctuations in motor output (P = 0.003) were greater during the position task compared with the force task. Consistent with these differences, mean discharge rate declined at a greater rate during the position task (P = 0.03), and the coefficient of variation for discharge rate increased only during the position task (P = 0.02). Furthermore, more motor units were recruited during the position task compared with the force task (P = 0.01). These findings indicate that despite a comparable net muscle torque, the rate of increase in the motor output from the spinal cord was greater during the position task.

Action Potentials↗