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Casimiro Javierre

Publications and source records attributed to Casimiro Javierre.

4 recordsLinked to original sources

Other relevant components of nuts: phytosterols, folate and minerals.

Nuts contain significant amounts of essential micronutrients that are associated with an improved health status when consumed at doses beyond those necessary to prevent deficiency states. Nuts do not contain cholesterol, but they are rich in chemically related phytosterols, a class of compounds that interfere with intestinal cholesterol absorption and thus help lower blood cholesterol. Nuts also contain folate, a B-vitamin necessary for normal cellular function that plays an important role in detoxifying homocysteine, a sulphur-containing amino acid with atherothrombotic properties that accumulates in plasma when folate status is subnormal. Compared to other common foodstuffs, nuts have an optimal nutritional density with respect to healthy minerals, such as calcium, magnesium and potassium. Like that of most vegetables, the sodium content of nuts is very low. A high intake of calcium, magnesium and potassium, together with a low sodium intake, is associated with protection against bone demineralisation, arterial hypertension, insulin resistance, and overall cardiovascular risk. Phytosterols might justify part of the cholesterol-lowering effect of nut intake beyond that attributable to fatty acid exchange, while the mineral richness of nuts probably contributes to the prevention of diabetes and coronary heart disease observed in epidemiological studies in association with frequent nut consumption.

Calcium↗

Human behaviour and development under high-altitude conditions.

Although we are far from a universally accepted pattern of impaired function at altitude, there is evidence indicating motor, perceptual, memory and behavioural deficits in adults. Even relatively low altitudes (2500 m) may delay reaction time, and impair motor function. Extreme altitude exposure (>5000 m) may result in more pronounced impairment that can persist after returning to the lowlands. Research into the effects of altitude exposure earlier in development is lacking by comparison. Un-acclimatized children can suffer from acute mountain sickness, and, in native populations born at altitude, subtle cognitive and behavioural deficits suggest incomplete adaptation to hypoxia. The study of neurobehavioural functioning at altitude may provide important information about the effects of clinical hypoxia on the human brain and behavioural development.

Altitude↗

Heritability of explosive power and anaerobic capacity in humans.

There is a disparity in the information about the heritability of the response of muscle anaerobic metabolism to exercise and the use of explosive power, as well as a lack of information concerning the genetic determinants of this form of work, as measured using different specific physical tests. We applied a battery of some of the commonly employed procedures (Ergojump, Wingate, maximal accumulated oxygen deficit, excess post-exercise oxygen consumption, and delta lactate concentration) to a group of 32 Caucasian male twins, 8 monozygotic and 8 dizygotic pairs, who had similar environmental backgrounds. Results were studied using a heritability index (HI). Zygosity was determined using the identity of erythrocyte antigens, protein and enzyme polymorphism and human leucocyte antigen serologic types between co-twins. Significant HI values (P< 0.05) were found in the following tests: maximal 5 s power (HI = 0.74) and total power in a 30 s interval (HI = 0.84) in the Wingate test, maximal lactate concentration (HI = 0.82) and delta lactate concentration (HI = 0.84) in the maximal progressive test, as well as in the 2nd (HI = 0.93) and in the 3rd min (HI = 0.92) of recovery after the deficit test. In this study, the most relevant findings were: firstly, significant HI values for many of the variables studied; secondly, the HI values of the parameters used to evaluate explosive power were higher than those of lactic acid capacity and thirdly, the HI of certain variables from different tests measuring, in theory, similar qualities, were different.

Adult↗